Journal of Internal Medicine Concepts & Practice ›› 2025, Vol. 20 ›› Issue (01): 59-62.doi: 10.16138/j.1673-6087.2025.01.12

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Treatment of hypertensive patients with insulin resistance from the spleen

LI Hua1, YANG Hua2()   

  1. 1. Department of Hypertension, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
    2. Department of Endocrinology and Metabolism, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200030, China
  • Received:2024-11-11 Online:2025-02-28 Published:2025-04-30
  • Contact: YANG Hua E-mail:yanghua@longhua.net

Abstract:

Insulin resistance is the common pathological basis for various metabolic-related diseases, including hypertension, and is a root cause of the metabolic syndrome. In traditional Chinese medicine, the core pathogenesis of insulin resistance is considered as spleen deficiency. The hypertensive patients with insulin resistance are more likely to be the type of stagnation of phlegm dampness. Through treating hypertensive patients with insulin resistance from the spleen, the various components of metabolic syndrome can be managed in the same disease category. The research on correlation between intestinal flora imbalance and mitochondrial dysfunction provides a theoretical basis for the treatment of the patients from spleen.

Key words: Treatment from spleen, Hypertension, Insulin resistance, Intestinal flora, Mitochondrial function

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