Journal of Internal Medicine Concepts & Practice ›› 2023, Vol. 18 ›› Issue (03): 141-145.doi: 10.16138/j.1673-6087.2023.03.002
• Original article • Previous Articles Next Articles
LUO Yadan1a,2, YUAN Liying1a,2, LU Yide1b, WANG Ziqiu1a,3, WANG Zhaohui1a()
Received:
2022-03-10
Online:
2023-06-30
Published:
2023-08-07
CLC Number:
LUO Yadan, YUAN Liying, LU Yide, WANG Ziqiu, WANG Zhaohui. Investigation of serum uric acid level in adult patients and analysis of related influencing factors[J]. Journal of Internal Medicine Concepts & Practice, 2023, 18(03): 141-145.
组别 | 男性 | 女性 | χ2 | P |
---|---|---|---|---|
18~30岁 | 29.21(772/2 643) | 13.95(310/2 223) | 162.695 | <0.001 |
31~40岁 | 28.47(1 158/4 067) | 13.99(390/3 003) | 242.250 | <0.001 |
41~50岁 | 26.29(981/3 732) | 10.88(338/3 107) | 258.557 | <0.001 |
51~60岁 | 19.94(1 088/5 457) | 15.48(622/4 017) | 31.025 | <0.001 |
61~70岁 | 19.22(1 267/6 593) | 19.56(935/4 780) | 0.209 | 0.647 |
71岁以上 | 19.57(900/4 599) | 27.20(783/2 879) | 59.063 | <0.001 |
合计 | 22.76(6 166/27 091) | 16.88(3 378/20 009) | 246.099 | <0.001 |
组别 | 总体水平 | 男性 | 女性 | |||
---|---|---|---|---|---|---|
n | 血尿酸 | n | 血尿酸 | |||
18~30岁 | 334.21±103.40 | 2 643 | 376.98±93.69 | 2 223 | 283.36±90.60 | |
31~40岁 | 331.62±105.67 | 4 067 | 375.38±100.79 | 3 003 | 272.36±80.181) | |
41~50岁 | 320.27±103.631)2) | 3 732 | 363.49±99.761)2) | 3 107 | 268.35±82.141) | |
51~60岁 | 313.86±111.561)2)3) | 5 457 | 336.45±119.011)2)3) | 4 017 | 283.17±92.072)3) | |
61~70岁 | 315.51±110.331)2)3) | 6 593 | 336.04±113.921)2)3) | 4 780 | 287.18±98.412)3)4) | |
71岁以上 | 322.61±119.991)2)4)5) | 4 599 | 329.92±120.531)2)3)4)5) | 2 879 | 310.94±118.211)2)3)4)5) |
血尿酸分级(μmol/L) | n | 男性 | 女性 | χ2 | P |
---|---|---|---|---|---|
0~179 | 3 811 | 1 794(6.62) | 2 017(10.08) | 185.092 9 | <.0001 |
180~300 | 17 075 | 6 627(24.46) | 10 448(52.22) | 3 836.140 8 | <.0001 |
301~359 | 10 483 | 6 356(23.46) | 4 127(20.63) | 53.493 3 | <.0001 |
360~419 | 8 006 | 6 064(22.38) | 1 942(9.71) | 1 311.172 4 | <.0001 |
420~479 | 4 380 | 3 549(13.10) | 831(4.15) | 1 092.286 2 | <.0001 |
480~539 | 1 948 | 1 607(5.93) | 341(1.70) | 518.798 3 | <.0001 |
540以上 | 1 397 | 1 094(4.04) | 303(1.51) | 254.731 3 | <.0001 |
合计 | 47 100 | 27 091(100.00) | 20 009(100.00) | / | / |
部门 | n | 血尿酸阳性 [n(%)] | HUA阳性者血尿酸 水平(μmol/L ) |
---|---|---|---|
肾脏病区 | 401 | 184(45.89) | 498.02±109.76 |
门诊心外科 | 82 | 37(45.12) | 477.57±66.52 |
门诊高血压 | 809 | 290(35.85) | 461.22±62.52 |
门急诊泌外科 | 990 | 340(34.34) | 468.53±79.63 |
产休病区 | 132 | 44(33.33) | 505.02±131.54 |
门诊肾脏内科 | 3 432 | 1 129(32.90) | 465.95±70.53 |
门诊肝移植 | 37 | 12(32.43) | 492.54±82.15 |
预防保健科 | 111 | 34(30.63) | 485.54±85.78 |
高血压病区 | 113 | 33(29.20) | 488.53±81.87 |
门诊核医学 | 100 | 29(29.00) | 464.93±79.49 |
[1] | 张彩霞, 侯艳培, 李冰. 高尿酸血症的肾损害[J]. 中国中西医结合肾病杂志, 2019, 20(4): 366-368. |
[2] | 薛晓梅, 任伟, 闫飞, 等. 高尿酸血症病人尿液pH值水平及其影响因素分析[J]. 青岛大学学报(医学版), 2020, 56(5): 576-579. |
[3] |
Park J, Kim Y. Associations of blood heavy metals with uric acid in the Korean general population: analysis of data from the 2016-2017 Korean national health and nutrition examination survey[J]. Biol Trace Elem Res, 2021, 199(1): 102-112.
doi: 10.1007/s12011-020-02152-5 |
[4] |
Jha V, Garcia-Garcia G, Iseki K, et al. Chronic kidney disease: global dimension and perspectives[J]. Lancet, 2013, 382(9888): 260-272.
doi: 10.1016/S0140-6736(13)60687-X pmid: 23727169 |
[5] |
Huang G, Xu J, Zhang T, et al. Hyperuricemia is associated with metabolic syndrome in the community very elderly in Chengdu[J]. Sci Rep, 2020, 10(1): 8678.
doi: 10.1038/s41598-020-65605-w pmid: 32457306 |
[6] | 许敏锐, 强德仁, 周义红, 等. 常州农村社区35-70岁人群代谢综合征及其组分与高尿酸血症的相关性研究[J]. 现代预防医学, 2020, 47(9): 1607-1611. |
[7] | 闫慧明, 安燕, 齐革清, 等. 包头地区罹患高尿酸血症的相关因素研究[J]. 风湿病与关节炎, 2020, 9(4): 27-30. |
[8] | 中国医师协会肾脏内科医师分会. 中国肾脏疾病高尿酸血症诊治的实践指南(2017版)[J]. 中华医学杂志, 2017, 97(25): 1927-1936. |
[9] | Liu R, Han C, Wu D, et al. Prevalence of hyperuricemia and gout in mainland China from 2000 to 2014: a systematic review and meta-analysis[J]. Biomed Res Int, 2015, 2015: 762820. |
[10] | 吕雪霞, 胡吉东. 高尿酸血症患病率调查及临床影响分析[J]. 临床检验杂志(电子版), 2020, 9(1): 34-35. |
[11] |
Zhou Z, Li Z, Wang C, et al. Common variants in the SLC28A2 gene are associated with serum uric acid level and hyperuricemia and gout in Han Chinese[J]. Hereditas, 2019, 156: 4.
doi: 10.1186/s41065-018-0078-0 |
[12] |
Kaewput W, Thongprayoon C, Rangsin R, et al. Association between serum uric acid and chronic kidney disease in patients with hypertension: a multicenter nationwide cross-sectional study[J]. J Evid Based Med, 2019, 12(4): 235-242.
doi: 10.1111/jebm.v12.4 URL |
[13] |
Lu J, He Y, Cui L, et al. Hyperuricemia predisposes to the onset of diabetes via promoting pancreatic β-cell death in uricase-deficient male mice[J]. Diabetes, 2020, 69(6): 1149-1163.
doi: 10.2337/db19-0704 URL |
[14] |
Vinuthinee-Naidu MN, Zunaina E, Azreen-Redzal A, et al. Correlation of retinal nerve fibre layer and macular thickness with serum uric acid among type 2 diabetes mellitus[J]. BMC Ophthalmol, 2017, 17(1): 91.
doi: 10.1186/s12886-017-0486-3 pmid: 28615022 |
[15] |
Lohsoonthorn V, Dhanamun B, Williams MA. Prevalence of hyperuricemia and its relationship with metabolic syndrome in Thai adults receiving annual health exams[J]. Arch Med Res, 2006, 37(7): 883-889.
pmid: 16971230 |
[16] |
Qiu L, Cheng XQ, Wu J, et al. Prevalence of hyperuricemia and its related risk factors in healthy adults from Northern and Northeastern Chinese provinces[J]. BMC Public Health, 2013, 13: 664.
doi: 10.1186/1471-2458-13-664 pmid: 23866159 |
[17] |
Huang YP, Zheng T, Zhang DH, et al. Community-based study on elderly CKD subjects and the associated risk factors[J]. Ren Fail, 2016, 38(10): 1672-1676.
doi: 10.1080/0886022X.2016.1229987 URL |
[18] |
Chen N, Wang W, Huang Y, et al. Community-based study on CKD subjects and the associated risk factors[J]. Nephrol Dial Transplant, 2009, 24(7): 2117-2123.
doi: 10.1093/ndt/gfn767 URL |
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