乳汁葡萄球菌属细菌与哺乳期乳腺炎临床特征的关联分析

doi:10.16139/j.1007-9610.2018.05.015

外科理论与实践 ›› 2018, Vol. 23 ›› Issue (05): 450-455.doi: 10.16139/j.1007-9610.2018.05.015

乳汁葡萄球菌属细菌与哺乳期乳腺炎临床特征的关联分析

陶颖娜^1,2, 万华¹, 仲姗姗³, 冯佳梅¹, 高晴倩¹

1.上海中医药大学附属曙光医院乳腺科,上海 200021;
2.上海市普陀区妇婴保健院乳腺科,上海 200062;
3.上海市黄浦区中心医院中医外科,上海 200002

收稿日期:2017-06-20 出版日期:2018-09-25 发布日期:2020-07-25
通讯作者: 万华,E-mail: drwanhua@163.com
基金资助:
上海市卫生和计划生育委员会中医药科研专项（2016LQ020）; 上海市科学技术委员会科研计划项目（14401971000）; 上海市卫生和计划生育委员会中医薄弱领域专科建设项目

Associations analysis between Staphylococcus in milk and clinical features of lactational mastitis

TAO Yingna^1,2, WAN Hua¹, ZHONG Shanshan³, FENG Jiamei¹, GAO Qingqian¹

1. Department of Breast, Shuguang Hospital Affiliated to Shanghai Traditional Chinese Medicine University, Shanghai 200021, China;
2. Department of Breast, Shanghai Putuo District Maternity and Child Care Center, Shanghai 200062, China;
3. Surgery of Traditional Chinese Medicine,Shanghai Huangpu District Central Hospital, Shanghai 200002, China

Received:2017-06-20 Online:2018-09-25 Published:2020-07-25

摘要/Abstract

摘要： 目的: 探讨乳汁中的葡萄球菌属及该属各菌种与哺乳期乳腺炎临床特征的相关性。方法: 2016年6月至2017年5月上海中医药大学附属曙光医院乳腺科的哺乳期乳腺炎病人63例,所有病人皆行双侧乳汁细菌培养,共126例乳汁样本。应用Spearman相关系数的简单相关分析和Apriori算法的关联规则分析,分析葡萄球菌属中菌种与临床特征的相关性。结果: 乳汁细菌培养结果与哺乳期乳腺炎临床特征具有相关性。葡萄球菌属及金黄色葡萄球菌与哺乳期乳腺炎的临床特征具有相关性;而表皮葡萄球菌、缓慢葡萄球菌则无相关关系。无菌只与哺乳期乳腺炎的乳房疼痛VAS评分、红肿压痛症状相关,但支持度低于葡萄球菌属细菌。结论: 乳汁细菌培养是哺乳期乳腺炎诊断的有效方法。葡萄球菌属与哺乳期乳腺炎临床特征的相关性取决于该属菌种的不同致病性。

关键词: 哺乳期乳腺炎, 乳汁细菌培养, 葡萄球菌属, 临床特征

Abstract: Objective To investigate association between Staphylococcus spp. including species and the clinical features of lactational mastitis. Methods From June 2016 to May 2017, 63 patients with lactational mastitis in Department of Breast Shuguang Hospital Affiliated to Shanghai Traditional Chinese Medicine University were included in this study. A total of 126 milk samples were collected from bilateral breast of the patients for bacterial culture of milk. Correlation between Staphylococcus and clinical features was studied using Spearman correlation and association rule analysis with Apriori algorithm. Results The correlation was present between the results of bacterial culture of milk and clinical feature of the patients with lactational mastitis. The clinical features were related to Staphylococcus spp, or Staphylococcus aureus, but not to Staphylococcus epidermidis or Staphylococcus lentus. Only negative result of bacterial culture of milk was associated to the features such as VAS score of breast pain, redness and swelling, tenderness. However, the support degree of association of negative bacterial milk was lower than that of association of Staphylococcus. Conclusions Bacterial culture of milk should be the effective approach to diagnose lactational mastitis. The correlation between Staphylococcus spp. and clinical features of lactational mastitis might be based on the different pathogenicity of genus.

Key words: Lactational mastitis, Bacterial culture of milk, Staphylococcus, Clinical feature

中图分类号:

R655.8

陶颖娜, 万华, 仲姗姗, 冯佳梅, 高晴倩. 乳汁葡萄球菌属细菌与哺乳期乳腺炎临床特征的关联分析[J]. 外科理论与实践, 2018, 23(05): 450-455.

TAO Yingna, WAN Hua, ZHONG Shanshan, FENG Jiamei, GAO Qingqian. Associations analysis between Staphylococcus in milk and clinical features of lactational mastitis[J]. Journal of Surgery Concepts & Practice, 2018, 23(05): 450-455.

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乳汁葡萄球菌属细菌与哺乳期乳腺炎临床特征的关联分析

Associations analysis between Staphylococcus in milk and clinical features of lactational mastitis

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