组织工程与重建外科杂志

组织工程与重建外科杂志 ›› 2019, Vol. 15 ›› Issue (2): 95-97.doi: 10.3969/j.issn.1673-0364.2019.02.009

• 论著 • 上一篇    下一篇

强脉冲光（420 nm+560 nm）联合无针水光治疗难治性痤疮的临床疗效

沈悦，张懿，徐晶，刘武林   

  1. 南京医科大学附属苏州医院(苏州市立医院北区)
  • 收稿日期:2018-12-18 修回日期:2019-02-01 出版日期:2019-04-20 发布日期:2019-04-20
  • 作者简介:刘武林(E-mail:liuwlin650@sohu.com)。

Effect of Intense Pulsed Light(420 nm+560 nm)Combined with Needle Free Water Light in the Treatment of Refractory Acne

SHEN Yue,ZHANG Yi,XU Jing,LIU Wulin   

  1. The Affiliated Suzhou Hospital of Nanjing Medical University; Suzhou Municipal Hospital,Suzhou 215008,China
  • Received:2018-12-18 Revised:2019-02-01 Online:2019-04-20 Published:2019-04-20

摘要： 目的 探讨强脉冲光(420 nm+560 nm)联合无针水光治疗难治性痤疮的临床疗效。方法 2017年2月至11月,难治性痤疮患者90例随机分为两组,对照组使用强脉冲光(420 nm+560 nm)进行治疗,实验组在此基础上联合使用无针水光进行治疗。比较两组患者痤疮部位的色素沉淀率,治疗后颊部、额部、颞部仍存在痤疮的人数,治疗有效率以及不良反应发生的例数。结果 实验组痤疮部位的色素沉淀率显著低于对照组(P<0.05);实验组治疗后颊部、额部、颞部仍存在痤疮的人数明显少于对照组(P<0.05);实验组治疗有效率明显高于对照组(P<0.05);实验组不良反应发生的例数明显少于对照组(P<0.05)。结论 对难治性痤疮患者采取强脉冲光(420 nm+560 nm)联合无针水光进行治疗,疗效显著,不良反应少,值得临床推广应用。

关键词: 强脉冲光, 无针水光, 难治性痤疮, 色素沉淀, 不良反应

Abstract: Objective To investigate the effect of intense pulsed light(420 nm+560 nm)combined with needle free water light in the treatment of refractory acne.Methods From February 2017 to November 2017,90 patients with refractory acne were randomly divided into two groups:control group(n=45)and experimental group(n=45).The patients in the control group were treated with intense pulsed light(420 nm+560 nm),and the patients in the experimental group were treated by needle-free water light based on intense pulsed light.The pigmentation rate of the acne,the number of patients with acne in cheek,forehead and temple after treatment,the treatment efficiency and the number of patients with adverse reactions in the two groups were all compared.Results The pigmentation rate of acne in the experimental group was significantly lower than that in the control group(P<0.05).After treatment,the patients with acne in cheek,forehead and temple of the experimental group were significantly less than that of the control group(P<0.05).The effective rate of the experimental group was significantly higher than that of the control group(P<0.05).The number of adverse reactions in the experimental group was significantly less than that in the control group(P<0.05).Conclusion Intense pulsed light(420 nm+560 nm)combined with needle-free water light is effective and safe in the treatment of refractory acne.It is worthy of clinical promotion.

Key words: Intense pulsed light, Needle free water light, Refractory acne, Pigmentation, Adverse reactions

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