Abstract: Objective To evaluate the therapeutic effect and safety of intralesional lauromacrogol injection in the treat-ment of venous malformation of glans penis. Methods From Jan 2011 to May 2013, 15 patients with venous malformation of the glans penis were treated with percutaneous intralesional injection of lauromacrogol. Injections were administrated under epidural anesthesia at a dose of 0.5-2.0 mL. Patients were treated once 2 months for 1 to 4 times. Results All the patients experienced transient erythema and edema without bleeding and infection, whereas local diabrosis occurred in only 1 patient. There were 2 patients complained of light pain after treatment. After followed up for 12 months to 3 years, all patients were cured without pigment alteration, abnormalities and erectile dysfunction. Conclusion It is considerd that intralesional in-jection with lauromacrogol is a safe and effective method for the treatment of venous malformation of the glans penis with no influence on appearance and function, which can be carried out easily and shows a low postoperative infection rate, so that it should be suggested as first choice of venous malformation in glans penis.

Key words: Lauromacrogol, Venous malformation, Glans penis, Intralesional injection