Clinical Application of Auto-hBMSCs Acting as Seeding Cell for Tissue Engineered Bone on the Cranial Defects

doi:10.3969/j.issn.1673-0364.2009.06.002

Journal of Tissue Engineering and Reconstructive Surgery ›› 2009, Vol. 5 ›› Issue (3): 125-127.doi: 10.3969/j.issn.1673-0364.2009.06.002

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Clinical Application of Auto-hBMSCs Acting as Seeding Cell for Tissue Engineered Bone on the Cranial Defects

WANG Yougang¹,LI Xinqing¹,LI Chunhe¹,WU Zhiyuan¹,CUI Lei²,LIU Guangpeng²,LI Yulin²,SUN Jian²

1 Changzhou Second Hospital Affiliated Nanjin Medical University;Changzhou 213000;China;2 Shanghai Tissue Engineering Research and Development Center;Shanghai 200235;China.;

Published:2020-07-23
Contact: 常州市卫生局重大科研课题(ZD200610)

Abstract

Abstract: Objective To investigate the clinical effect of hBMSCs acting as seeding cell for tissue engineer bone on the cranial defects.Methods From June 2006 to February 2007,four patients with traumatic cranial defect were treated by using auto-hBMSCs acting seeding cell for tissue engineered bone.Autogenic hBMSCs were isolated,proliferated and induced in vitro,then combined with partially demineralized bone matrix.After co-cultured for 1 week,the cell/scaffold complexes were used for implantation.Gross observation...

Key words: Human bone marrow stromal cells（hBMSCs）, Tissue engineering, Cranial defects, Clinical application

CLC Number:

R687.3+4

WANG Yougang,LI Xinqing,LI Chunhe,WU Zhiyuan,CUI Lei,LIU Guangpeng,LI Yulin,SUN Jian. Clinical Application of Auto-hBMSCs Acting as Seeding Cell for Tissue Engineered Bone on the Cranial Defects[J]. Journal of Tissue Engineering and Reconstructive Surgery, 2009, 5(3): 125-127.

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Clinical Application of Auto-hBMSCs Acting as Seeding Cell for Tissue Engineered Bone on the Cranial Defects

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