Abstract: Objective To observe the clinical effects of vacuum sealing drainage(VSD)combined with autologous platelet-rich gel(APG)for the treatment of diabetic foot.Methods From July 2016 to February 2018,60 patients with diabetic foot ulcer(DFU)were randomly divided into two groups:experimental group(n=30)and control group(n=30).The experimental group was treated by VSD combined with APG,while the control group was treated by VSD only.The cure rate,healing time,time of bacterial turnover and histological appearance of the two groups were compared.Results The cure rate of the experimental group was higher than that of the control group at all time points(P<0.05).The time of wound healing and bacterial turnover in experimental group were both lower than that in control group(P<0.05).Conclusion VSD combined with APG for the treatment of DFU is effective in promoting the wound healing and shortening the healing time.

Key words: Autologous platelet-rich gel, Vacuum sealing drainage, Diabetic foot