Abstract: Objective　To analyze dermatoscopic patterns and characteristics of acquired melanocyte nevus (AMN) in Chinese Han population. Methods　Clinical data and dermatoscopic findings of patients with pathologically confirmed acquired melanocytic nevus from December 2020 to March 2021 were collected, and the correlation between the dermatoscopic pattern and age, diameter, location and pathology was retrospectively analyzed. Results　A total of 1 918 lesions were collected from 1 463 patients, with a male to female ratio of 0.35:1. The age distribution was from 4 to 75 years old, and the 20 to 40 years old group(69.2%) was the largest. The most common dermatoscopic patterns were spherical (37.1%) and pseudoreticular(36.8%).  Pseudoreticular pattern was most common in <20 years old group(41.0%) whereas spherical pattern in ≥20 years old group(P<0.05).  The most lesions were found in 5~9 mm group, and pseudoreticular pattern(36.7%) and spherical pattern (35.8%) were the first two patterns in it. The dermatoscopic pattern was significantly correlated with the site on body surface (P<0.001). The most common pattern was pseudoreticular pattern in head, face and neck (99.3%), spherical pattern in trunk (62.1%), while the cutaneous furrow parallel pattern, fibrillar pattern and grid pattern were only found in limbs and palmoplantar. Intradermal nevus was the most common pathological type, and there were significant differences in the composition ratio of reticular pattern and parallel sulcus pattern among pathological types(P<0.05).  Conclusion　The dermatoscopic pattern of acquired melanocytic nevus has certain correlation with age, diameter and location. Although it cannot correspond with histopathology one by one, it still plays an irreplaceable role in the differentiation of benign and malignant pigmented lesions, and can reduce the probability of unnecessary biopsy or surgical treatment.

Key words: Acquired melanocytic nevi, 　Dermatoscopic pattern, 　Age, 　Diameter, 　Location, 　Histological subtype