Objective For large area skin defects， using 3D printing technology to perform free skin transplantation more accurately. Methods 3D scanning technology was used to model the affected limb， and the skin defect area was constructed. The skin defect model was printed with resin material. The skin removal design of the donor area was carried out before surgery to ensure that the skin removal area of the donor area was closed without tension. The cutting and splicing points were marked. After cutting the skin according to the 3D model， point-to-point splicing was carried out， and the wound surface was covered for wound skin grafting. Results 3D printing technology was used to plan the preoperative skin donor area， which better covered the wound， and the donor area was completely tension-free suture， greatly reducing the operation time， and improving the survival rate of skin transplantation on large irregular wounds. Conclusion The use of 3D printing for preoperative skin removal planning can improve the efficiency of surgery， greatly reduce the damage of the donor area， and provide better personalized wound repair for large-scale irregular skin defects.

Skin defect, Wound repair, Digital design