精子碎片指数与精子形态的关系研究

doi:10.16150/j.1671-2870.2018.01.018

摘要/Abstract

摘要： 目的：探讨精子DNA碎片指数（DNA fragmentation index, DFI）与精子形态学之间的相关性。方法：回顾性分析3 068例男性患者的精液检查结果,将精子DFI分为<15%、15%~30%、>30%共3组,再根据精子形态学检查结果,按照正常形态精子所占比例<4%、4%~10%、>10%将精子分为3组,分析精子不同形态学分组与精子DFI分组间的关系。结果：不同精子DFI分组的正常形态、头部畸形、混合畸形百分比差异无统计学意义（P均>0.05）;不同的精子正常形态率分组间的精子DFI差异无统计学意义（P均>0.05）,用Spearson相关性分析精子DFI与精子形态之间的相关性,结果发现两者间无相关性。结论：本研究发现精子DFI与精子形态学之间没有相关性。

关键词: 精子DNA碎片指数, 精子形态, 男性不育, 相关性

Abstract: Objective: To study the correlation between sperm DNA fragmentation index (DFI) and sperm morphology in male semen. Methods: A total of 3 068 male subjects were enrolled and their semen samples were obtained and analyzed. According to the sperm DFI, the semen samples were divided into three groups: DFI<15%, 15%-30%, >30%. According to the percentage of spermatocytes with normal morphology, the sperm were divided into three groups: <4%, 4%-10%, > 10%. The relationship between DNA fragment index and sperm morphology in these groups was analyzed. Results: There was no significant difference in rates of normal morphology, head deformity and mixed deformity between groups with different sperm DFI index(P>0.05). There was no significant difference in sperm DFI between groups with different percen-tage of normal morphology of sperm. There was no significant correlation between different sperm normal morphology group and sperm DFI group(P>0.05). Conclusions: This study showed that there is no correlation between sperm DFI and sperm morphology.

Key words: The sperm DNA fragmentation index, Sperm morphology, Male infertility, Correlation

中图分类号:

R691.9

刘依萍, 唐圆圆, 徐奎, 滕晓明. 精子碎片指数与精子形态的关系研究[J]. 诊断学理论与实践, 2018, 17(01): 98-101.

LIU Yiping, TANG Yuanyuan, XU Kui, TENG Xiaoming. Correlation between sperm DNA fragmentation index and sperm morphology[J]. Journal of Diagnostics Concepts & Practice, 2018, 17(01): 98-101.

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