人类假基因在以肝癌为主的肿瘤中的作用及研究进展

doi:10.16150/j.1671-2870.2019.05.022

摘要/Abstract

关键词: 假基因, 功能, 作用机制, 肝癌

中图分类号:

R735

蔡业冰, 任家俊, 郝风节, 叶枫, 杨宇尘, 龚笑勇, 马迪, 王俊青, 陈拥军. 人类假基因在以肝癌为主的肿瘤中的作用及研究进展[J]. 诊断学理论与实践, 2019, 18(05): 590-594.

参考文献 41

[1]	Chen W, Zheng R, Baade PD, et al. Cancer statistics in China, 2015[J]. CA Cancer J Clin, 2016, 66(2):115-132. doi: 10.3322/caac.21338 URL
[2]	Jacq C, Milller JR, Browldee GG. A pseudogene structure in 5S DNA of Xenopus laevis[J]. Cell, 1977, 12(1):109-120. pmid: 561661
[3]	Millson A, Lewis T, Pesaran T, et al. Processed Pseudogene Confounding Deletion/Duplication Assays for SMAD4[J]. J Mol Diagn, 2015, 17(5):576-582. doi: 10.1016/j.jmoldx.2015.05.005 pmid: 26165824
[4]	Zhang ZD, Frankish A, Hunt T, et al. Identification and analysis of unitary pseudogenes: historic and contemporary gene losses in humans and other primates[J]. Genome Biol, 2010, 11(3):R26. doi: 10.1186/gb-2010-11-3-r26 URL
[5]	刘国庆, 李宏. 人类基因组中加工假基因分布与重组率和基因密度的关系[J]. 生物物理学报, 2008, 24(5):371-378.
[6]	Hui L, Cheng Z, Feng L. Identification and function analysis of pseudogenes[J]. Sheng Wu Gong Cheng Xue Bao, 2013, 29(5):551-567.
[7]	Glusman G, Sosinsky A, Ben-Asher E, et al. Sequence, structure, and evolution of a complete human olfactory receptor gene cluster[J]. Genomics, 2000, 63(2):227-245. pmid: 10673334
[8]	Frank AC, Amiri H, Andersson SG. Genome deterioration: loss of repeated sequences and accumulation of junk DNA[J]. Genetica, 2002, 115(1):1-12. doi: 10.1023/A:1016064511533 URL
[9]	赵云航, 康相涛, 孙桂荣, 等. 假基因对的研究现状及展望[J]. 中国畜牧兽医, 2008, 35(7):70-72.
[10]	Gray TA, Wilson A, Fortin PJ, et al. The putatively functional Mkrn1-p1 pseudogene is neither expressed nor imprinted, nor does it regulate its source gene in trans[J]. Proc Natl Acad Sci U S A, 2006, 103(32):12039-12044. doi: 10.1073/pnas.0602216103 URL
[11]	Wang W, Zhang J, Alvarez C, et al. The origin of the Jingwei gene and the complex modular structure of its parental gene, yellow emperor, in Drosophila melanogaster[J]. Mol Biol Evol, 2000, 17(9):1294-1301. pmid: 10958846
[12]	Torrents D, Suyama M, Zdobnov E, et al. A genome-wide survey of human pseudogenes[J]. Genome Res, 2003, 13(12):2559-2567. pmid: 14656963
[13]	Balakirev ES, Ayala FJ. Pseudogenes: are they "junk" or functional DNA?[J]. Annu Rev Genet, 2003; 37:123-151. pmid: 14616058
[14]	Khachane AN, Harrison PM. Assessing the genomic evidence for conserved transcribed pseudogenes under selection[J]. BMC Genomics, 2009, 10:435. doi: 10.1186/1471-2164-10-435 pmid: 19754956
[15]	Molineris I, Sales G, Bianchi F, et al. A new approach for the identification of processed pseudogenes[J]. J Comput Biol, 2010, 17(5):755-765. doi: 10.1089/cmb.2009.0027 pmid: 20500026
[16]	Chiefari E, Iiritano S, Paonessa F, et al. Pseudogene-mediated posttranscriptional silencing of HMGA1 can result in insulin resistance and type 2 diabetes[J]. Nat Commun, 2010, 1:40. doi: 10.1038/ncomms1040 pmid: 20975707
[17]	Xu L, Lu XY, Yi K, et al. Progress in research on pseudogenes[J]. Chemistry of Life, 2003(6):406-409.[未查到]
[18]	Boger ET, Sellers JR, Friedman TB. Human myosin XVBP is a transcribed pseudogene[J]. J Muscle Res Cell Motil, 2001, 22(5):477-483. doi: 10.1023/A:1014507705858 URL
[19]	Kalyana-Sundaram S, Kumar-Sinha C, Shankar S, et al. Expressed pseudogenes in the transcriptional landscape of human cancers[J]. Cell, 2012, 149(7):1622-1634. doi: 10.1016/j.cell.2012.04.041 pmid: 22726445
[20]	He J, Xie Q, Xu H, et al. Circular RNAs and cancer[J]. Cancer Lett, 2017, 396:138-144. doi: 10.1016/j.canlet.2017.03.027 URL
[21]	Conte F, Fiscon G, Chiara M, et al. Role of the long non-coding RNA PVT1 in the dysregulation of the ceRNA-ceRNA network in human breast cancer[J]. PLoS One, 2017, 12(2):e0171661. doi: 10.1371/journal.pone.0171661 URL
[22]	Zhang S, Dong X, Ji T, et al. Long non-coding RNA UCA1 promotes cell progression by acting as a competing endogenous RNA of ATF2 in prostate cancer[J]. Am J Transl Res, 2017, 9(2):366-375.
[23]	Chiu YC, Wang LJ, Lu TP, et al. Differential correlation analysis of glioblastoma reveals immune ceRNA interactions predictive of patient survival[J]. BMC Bioinformatics, 2017, 18(1):132. doi: 10.1186/s12859-017-1557-4 URL
[24]	Han L, Yuan Y, Zheng S, et al. The Pan-Cancer analysis of pseudogene expression reveals biologically and clinically relevant tumour subtypes[J]. Nat Commun, 2014, 5:3963. doi: 10.1038/ncomms4963 URL
[25]	Li S, Zou H, Shao YY, et al. Pseudogenes of annexin A2, novel prognosis biomarkers for diffuse gliomas[J]. Oncotarget, 2017, 8(63):106962-106975. doi: 10.18632/oncotarget.22197 URL
[26]	史燕妹, 牛义淳, 路明亮, 等. 竞争性内源RNA与消化系恶性肿瘤关联的研究进展[J]. 世界华人消化杂志, 2017, 25(7):596-601.
[27]	Sun T, Wong N. Transforming growth factor-β-induced long noncoding RNA promotes liver cancer metastasis via RNA-RNA crosstalk[J]. Hepatology, 2015, 61(2):722-724. doi: 10.1002/hep.27599 URL
[28]	Fang L, Du WW, Yang X, et al. Versican 3'-untranslated region (3'-UTR) functions as a ceRNA in inducing the development of hepatocellular carcinoma by regulating miRNA activity[J]. FASEB J, 2013, 27(3):907-919. doi: 10.1096/fj.12-220905 URL
[29]	Poursani EM, Mohammad Soltani B, Mowla SJ. Differential Expression of OCT4 Pseudogenes in Pluripotent and Tumor Cell Lines[J]. Cell J, 2016, 18(1):28-36. pmid: 27054116
[30]	Yu JW, Zhou LL. Advances in OCT4 pseudogenes in tumors[J]. Oncology Progress, 2018, 16(12):1451-1454.
[31]	Pan Y, Zhan L, Chen L, et al. POU5F1B promotes hepatocellular carcinoma proliferation by activating AKT[J]. Biomed Pharmacother, 2018, 100:374-380. doi: 10.1016/j.biopha.2018.02.023 URL
[32]	Kong Y, Zhang L, Huang Y, et al. Pseudogene PDIA3P1 promotes cell proliferation, migration and invasion, and suppresses apoptosis in hepatocellular carcinoma by regulating the p53 pathway[J]. Cancer Lett, 2017, 407:76-83. doi: 10.1016/j.canlet.2017.07.031 URL
[33]	Li B, Mao R, Liu C, et al. LncRNA FAL1 promotes cell proliferation and migration by acting as a CeRNA of miR-1236 in hepatocellular carcinoma cells[J]. Life Sci, 2018, 197:122-129. doi: 10.1016/j.lfs.2018.02.006 URL
[34]	Deng L, Yang SB, Xu FF, et al. Long noncoding RNA CCAT1 promotes hepatocellular carcinoma progression by functioning as let-7 sponge[J]. J Exp Clin Cancer Res, 2015, 34:18. doi: 10.1186/s13046-015-0136-7 URL
[35]	Yu W, Qiao Y, Tang X, et al. Tumor suppressor long non-coding RNA, MT1DP is negatively regulated by YAP and Runx2 to inhibit FoxA1 in liver cancer cells[J]. Cell Signal, 2014, 26(12):2961-2968. doi: 10.1016/j.cellsig.2014.09.011 URL
[36]	Chen CL, Tseng YW, Wu JC, et al. Suppression of hepatocellular carcinoma by baculovirus-mediated expression of long non-coding RNA PTENP1 and MicroRNA regulation[J]. Biomaterials, 2015, 44:71-81. doi: 10.1016/j.biomaterials.2014.12.023 URL
[37]	熊志勇, 姚志成, 范伟明, 等. 长链非编码RNA PTENP1基因抑制肝癌细胞增殖和迁移[J]. 中华肝脏外科手术学电子杂志, 2016, 5(2):119-123.
[38]	何倩倩, 王浩联, 张金平, 等. 肝细胞肝癌中AOC4P表达和临床意义[J]. 中国肿瘤临床, 2016, 43(8):344-347.
[39]	Bian Z, Jin L, Zhang J, et al. LncRNA-UCA1 enhances cell proliferation and 5-fluorouracil resistance in colorectal cancer by inhibiting miR-204-5p[J]. Sci Rep, 2016, 6:23892. doi: 10.1038/srep23892 URL
[40]	闫春晓, 武利萍, 谭莉霞, 等. 肝癌患者锌指蛋白281的表达水平及其对肝癌细胞增殖凋亡的影响[J]. 安徽医学, 2019, 40(6):):613-617.
[41]	段巧斌, 俞金龙. ceRNAs在结直肠癌中的研究进展[J]. 分子影像学杂志, 2018, 41(4):499-503.

人类假基因在以肝癌为主的肿瘤中的作用及研究进展

RichHTML

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

参考文献 41

相关文章 15

编辑推荐

Metrics

本文评价

[1]	何亲羽, 王伟, 陈立芬, 张雪蕾, 董治亚. LHCGR基因突变致家族性男性性早熟2例报告及文献复习[J]. 诊断学理论与实践, 2022, 21(05): 598-605.
[2]	孙艳艳, 兰信堂. 肺癌颅脑转移患者接受放射治疗后前庭功能受损1例[J]. 诊断学理论与实践, 2022, 21(05): 632-634.
[3]	桂燕萍, 陈晔芬, 施仲伟, 许燕. 超声心动图右室面积变化分数筛查左心室射血分数降低的心力衰竭患者心脏同步性研究[J]. 诊断学理论与实践, 2022, 21(03): 331-335.
[4]	中华医学会内分泌学分会. 新型冠状病毒肺炎疫情下甲状腺功能亢进症和甲状腺功能减退症管理专家建议[J]. 诊断学理论与实践, 2022, 21(02): 128-129.
[5]	中华医学会内分泌学分会. 新型冠状病毒肺炎疫情下肾上腺疾病管理专家建议[J]. 诊断学理论与实践, 2022, 21(02): 139-142.
[6]	张红, 朱梦梦. 新型冠状病毒肺炎疫情期间老年人进食安全护理[J]. 诊断学理论与实践, 2022, 21(02): 277-280.
[7]	杨田, 吉翔, 牛建梅, 孔晓晓, 吕明丽. 二维超声在产前胎儿胸腺发育评估中的应用[J]. 诊断学理论与实践, 2021, 20(05): 471-474.
[8]	吴冬梅, 吴丽莉, 陈佳, 刘坤. 淋巴上皮样肝细胞肝癌一例报告附文献复习[J]. 诊断学理论与实践, 2021, 20(05): 498-501.
[9]	苏长青. 从基础研究到临床转化应用谈肝癌的诊治进展[J]. 诊断学理论与实践, 2021, 20(05): 427-433.
[10]	李海. 慢加急肝衰竭的诊断标准及管理[J]. 诊断学理论与实践, 2021, 20(05): 434-438.
[11]	赵然, 詹维伟, 柳俊. 三维超声监测特发性低促性腺激素性性腺功能减退症无精子患者睾丸体积对患者生精功能的预测价值[J]. 诊断学理论与实践, 2021, 20(03): 279-283.
[12]	戎天艺, 花芸, 陈德艳, 何旻. 血清天冬酰胺内肽酶与急性大动脉粥样硬化型卒中间相关性的前瞻性研究[J]. 诊断学理论与实践, 2021, 20(02): 184-189.
[13]	徐丽梨, 王伟铭. 特发性肾性低尿酸血症相关的急性肾衰竭一例报告及文献复习[J]. 诊断学理论与实践, 2021, 20(02): 213-215.
[14]	汪楠, 郝风节, 王俊青. 肝细胞多倍体发生机制及其与肝细胞癌形成的相关性研究进展[J]. 诊断学理论与实践, 2020, 19(06): 618-621.
[15]	余红, 王一飞, 陈佳, 陈洁, 李斌. 青蒿素及其衍生物在皮肤疾病中的作用机制研究及临床应用[J]. 诊断学理论与实践, 2019, 18(2): 233-236.