Journal of Diagnostics Concepts & Practice ›› 2024, Vol. 23 ›› Issue (05): 517-523.doi: 10.16150/j.1671-2870.2024.05.008
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FENG Guowei, HUANG Xinyun, MENG Hongping, JIANG Xufeng, CHEN Kemin, LIN Xiaozhu()
Received:
2024-06-08
Accepted:
2024-10-08
Online:
2024-10-25
Published:
2025-02-25
Contact:
LIN Xiaozhu
E-mail:lxz11357@rjh.com.cn
CLC Number:
FENG Guowei, HUANG Xinyun, MENG Hongping, JIANG Xufeng, CHEN Kemin, LIN Xiaozhu. Value of 18F-fluorodeoxyglucose positron emission tomography/magnetic resonance imaging (18F-FDG PET/MRI) in diagnosis of postoperative recurrence of pancreatic cancer[J]. Journal of Diagnostics Concepts & Practice, 2024, 23(05): 517-523.
Table 1
Clinical information of 86 cases post-operative pancreatic cancer patients with 18F-FDG PET/MRI examination
Indice | Recurrence group | Non-recurrence group | Statistics value | P value |
---|---|---|---|---|
Gender(male/female) | 40/18 | 22/6 | χ2=0.866 | 0.446 |
Age(mean±standard deviation,year) | 62.2±10.1 | 61.4±8.2 | t=0.332 | 0.740 |
Height(mean±standard deviation,cm) | 168.2±7.7 | 167.9±7.3 | t=0.160 | 0.873 |
Body weight(mean±deviation,Kg) | 57.4±9.5 | 58.5±11.2 | t=-0.464 | 0.644 |
Blood glucose(mean±deviation,mmol/L) | 6.9±2.2 | 7.2±3.1 | t=-0.518 | 0.606 |
Time between operation and PET/MRI(median,day) | 306 | 365 | U=666.000 | 0.180 |
Location of tumor(pancreatic head and uncinate process/body and tail) | 27/31 | 12/16 | χ2=0.104 | 0.819 |
Tumor size(mean±standard deviation,cm) | 3.4±1.3 | 2.7±1.2 | 2.419 | 0.018 |
Figure 1
Follow-up PET/MRI of a post-operative pancreatic cancer patient showed recurrence in the surgical area A 56 years old man with radical surgery of pancreaticoduodenectomy for more than 16 months, had normal serum CA19-9 during follow-up after surgery. PET/MRI suggested recurrence in the surgical area. Subsequently, the patient underwent chemotherapy (albumin-bound paclitaxel + gemcitabine). A: A whole-body PET MIP image shows a high metabolic focus in the mid-upper abdomen (red arrow); B: A PET transverse image of the upper abdomen shows a high metabolic focus in front of the right side of the abdominal aorta, with SUVmax 12.5; C: A transverse T2 weighted image with fat suppression of the upper abdomen shows roughness around the superior mesenteric vein and superior mesenteric artery; D-E: Transverse diffusion weighted image (DWI) and apparent diffusion coefficient (ADC)map of the upper abdomen show high signal foci in front of the right side of the abdominal aorta on DWI, with low ADC; F-G: Transverse images of contrast enhanced T1 weighted image with fat suppression of the upper abdomen on late arterial phase and portal venous phase show thickening of the superior mesenteric artery and punctate abnormal signals beside the superior mesenteric vein.
Figure 2
Follow-up PET/MRI of a post-operative pancreatic cancer patient showed metastasis in the Ⅷ segment of the liver A 52 years old man, with radical surgery of pancreaticoduodenectomy for more than 13 months, had elevated CEA and CA19-9 during follow-up. PET/MRI suggested metastatic lesions in the right lobe of the liver. Subsequently, the patient underwent ablation of the hepatic lesion. A: A whole-body PET MIP image shows a high metabolic focus in the right lobe of the liver (red arrow), with SUVmax 7.2; B-C: Transverse diffusion weighted image(DWI)and apparent diffusion coefficient (ADC)map of the upper abdomen show high signal foci in the Ⅷ segment of the liver on DWI, with slightly reduced ADC; D: Transverse T2 weighted image of the upper abdomen shows a slightly high signal focus in the Ⅷ segment of the liver; E: Transverse T1weighted image(T1WI) of the upper abdomen shows a slightly low signal focus in the Ⅷ segment of the liver; F-G: Transverse contrast enhanced T1WI with fat suppression of the upper abdomen show slightly low signal foci in the Ⅷ segment of the liveron arterial and portal venous phases, with mild to moderate enhancement in the portal venous phase and blurred edges.
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