内科理论与实践 ›› 2024, Vol. 19 ›› Issue (01): 77-81.doi: 10.16138/j.1673-6087.2024.01.14

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糖尿病患者合并新型冠状病毒感染的研究进展

黄仙娜1, 陈云册1, 周敏2, 倪磊1,2()   

  1. 1.墨江哈尼族自治县人民医院呼吸与危重症医学科,云南 普洱 654899
    2.上海交通大学医学院附属瑞金医院呼吸与危重症医学科,上海 200025
  • 收稿日期:2023-10-30 出版日期:2024-02-29 发布日期:2024-04-28
  • 通讯作者: 倪磊 E-mail:nilei625@139.com

Research progress on diabetes patients combined with COVID-19 infection

HUANG Xianna1, CHEN Yunce1, ZHOU Min2, NI Lei1,2()   

  1. 1. Department of Respiratory and Critical Care Medicine, People’s Hospital of Mojiang Hani Autonomous County, Puer 654899, China
    2. Department of Respiratory and Critical Care Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
  • Received:2023-10-30 Online:2024-02-29 Published:2024-04-28
  • Contact: NI Lei E-mail:nilei625@139.com

摘要:

糖尿病患者不仅是新型冠状病毒(新冠)的易感人群,并且在感染新冠后容易出现免疫失衡、过度炎症反应、多脏器功能损伤等并发症,导致病情更为复杂,危重症的概率显著升高,应引起临床医师重视。本文通过回顾国内外相关文献,总结了新冠导致糖代谢异常的机制,以及糖尿病患者感染新冠的临床特点和血糖管理的原则,以提高对此类患者的临床认知和治疗成功率。

关键词: 新型冠状病毒, 糖尿病, 血管紧张素转化酶2, 细胞因子风暴

Abstract:

Diabetic patients are not only susceptible population to COVID-19 infection,but also prone to develop immune imbalance, excessive inflammatory responses, multi-organ dysfunction, and other complications after infection, resulting in complicated condition and a significantly increased risk of critical illness. Therefore, it requires more attention of clinicians. The article reviews the relevant domestic and international literatures and summarizes the mechanisms of abnormal glucose metabolism induced by COVID-19 infection, clinical characteristics of diabetes patients infected with COVID-19, and the principles of blood glucose management, to improve the clinical understanding and treatment success rate of such patients.

Key words: Severe acute respiratory syndrome coronavirus 2, Diabetes mellitus, Angiotensin-converting enzyme 2, Cytokine storm

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