内科理论与实践 ›› 2022, Vol. 17 ›› Issue (04): 344-348.doi: 10.16138/j.1673-6087.2022.04.015
收稿日期:
2021-11-25
出版日期:
2022-07-18
发布日期:
2022-08-08
通讯作者:
高艳虹
E-mail:gaoyanhong@xinhuamed.com.cn
基金资助:
Received:
2021-11-25
Online:
2022-07-18
Published:
2022-08-08
中图分类号:
高晶晶, 高艳虹. 早发2型糖尿病流行病学、临床特征及病因机制的研究进展[J]. 内科理论与实践, 2022, 17(04): 344-348.
[1] |
Cho NH, Shaw JE, Karuranga S, et al. IDF diabetes atlas: global estimates of diabetes prevalence for 2017 and projections for 2045[J]. Diabetes Res Clin Pract, 2018, 138: 271-281.
doi: 10.1016/j.diabres.2018.02.023 URL |
[2] |
Zheng Y, Ley SH, Hu FB. Global aetiology and epidemiology of type 2 diabetes mellitus and its complications[J]. Nat Rev Endocrinol, 2018, 14(2): 88-98.
doi: 10.1038/nrendo.2017.151 pmid: 29219149 |
[3] |
Viner R, White B, Christie D. Type 2 diabetes in adolescents: a severe phenotype posing major clinical challenges and public health burden[J]. Lancet, 2017, 389(10085): 2252-2260.
doi: 10.1016/S0140-6736(17)31371-5 URL |
[4] | International Diabetes Federation. IDF Diabetes Atlas[J]. 2017: 147. |
[5] | Sun H, Saeedi P, Karuranga S, et al. IDF Diabetes Atlas: global, regional and country-level diabetes prevalence estimates for 2021 and projections for 2045[J]. Diabetes Res Clin Pract, 2022, 183: 109119. |
[6] | Zhang Y, Ning G. Diabetes: young-onset type 2 diabetes mellitus-a challenge for Asia[J]. Nat Rev Endocrinol, 2014, 10(12): 703-704. |
[7] |
Wang L, Gao P, Zhang M, et al. Prevalence and ethnic pattern of diabetes and prediabetes in China in 2013[J]. JAMA, 2017, 317(24): 2515-2523.
doi: 10.1001/jama.2017.7596 URL |
[8] |
Ogurtsova K, da Rocha Fernandes JD, Huang Y, et al. IDF diabetes atlas: global estimates for the prevalence of diabetes for 2015 and 2040[J]. Diabetes Res Clin Pract, 2017, 128: 40-50.
doi: 10.1016/j.diabres.2017.03.024 URL |
[9] |
Candler TP, Mahmoud O, Lynn RM, et al. Continuing rise of type 2 diabetes incidence in children and young people in the UK[J]. Diabet Med, 2018, 35(6): 737-744.
doi: 10.1111/dme.13609 URL |
[10] | 刘杰, 顾天伟, 钟胜利, 等. 住院早发2型糖尿病患者代谢特征及慢性并发症情况[J]. 中华糖尿病杂志, 2020, 12(6): 387-392. |
[11] | Wilmot E, Idris I. Early onset type 2 diabetes: risk factors, clinical impact and management[J]. Ther Adv Chr-onic Dis, 2014, 5(6): 234-244. |
[12] |
Barrett T, Jalaludin MY, Turan S, et al. Rapid progression of type 2 diabetes and related complications in children and young people — a literature review[J]. Pediatr Diabetes, 2020, 21(2): 158-172.
doi: 10.1111/pedi.12953 URL |
[13] |
Yeung RO, Zhang Y, Luk A, et al. Metabolic profiles and treatment gaps in young-onset type 2 diabetes in Asia (the JADE programme)[J]. Lancet Diabetes Endocrinol, 2014, 2(12): 935-943.
doi: 10.1016/S2213-8587(14)70137-8 URL |
[14] |
Nanayakkara N, Curtis AJ, Heritier S, et al. Impact of age at type 2 diabetes mellitus diagnosis on mortality and vascular complications: systematic review and meta-analyses[J]. Diabetologia, 2021, 64(2): 275-287.
doi: 10.1007/s00125-020-05319-w pmid: 33313987 |
[15] | Wu Y, Wang Y, Zhang J, et al. Early-onset of type 2 diabetes mellitus is a risk factor for diabetic nephropathy progression: a biopsy-based study[J]. Aging (Albany NY), 2021, 13(6): 8146-8154. |
[16] |
Hui Y, Wang J, An Y, et al. Premature death and risk of cardiovascular disease in young-onset diabetes: a 23-year follow-up of the Da Qing Diabetes Study[J]. Endocrine, 2019, 65(1): 46-52.
doi: 10.1007/s12020-019-01928-7 URL |
[17] |
Huo L, Magliano DJ, Rancière F, et al. Impact of age at diagnosis and duration of type 2 diabetes on mortality in Australia 1997-2011[J]. Diabetologia, 2018, 61(5): 1055-1063.
doi: 10.1007/s00125-018-4544-z URL |
[18] |
Lascar N, Brown J, Pattison H, et al. Type 2 diabetes in adolescents and young adults[J]. Lancet Diabetes Endocrinol, 2018, 6(1): 69-80.
doi: 10.1016/S2213-8587(17)30186-9 URL |
[19] | 吕欣璐, 陈香均, 汪志红. 早发2型糖尿病:流行病学,危险因素及其与并发症的研究现状[J]. 世界最新医学信息文摘, 2020, 20(27): 94-95. |
[20] |
Magliano DJ, Sacre JW, Harding JL, et al. Young-onset type 2 diabetes mellitus - implications for morbidity and mortality[J]. Nat Rev Endocrinol, 2020, 16(6): 321-331.
doi: 10.1038/s41574-020-0334-z pmid: 32203408 |
[21] |
Zhou S, Meng X, Wang S, et al. A 3-year follow-up study of β-cell function in patients with early-onset type 2 diabetes[J]. Exp Ther Med, 2016, 12(2): 1097-1102.
doi: 10.3892/etm.2016.3394 URL |
[22] |
Zou X, Zhou X, Ji L, et al. The characteristics of newly diagnosed adult early-onset diabetes: a population-based cross-sectional study[J]. Sci Rep, 2017, 7: 46534.
doi: 10.1038/srep46534 URL |
[23] |
Mohan V, Amutha A, Ranjani H, et al. Associations of β-cell function and insulin resistance with youth-onset type 2 diabetes and prediabetes among Asian Indians[J]. Diabetes Technol Ther, 2013, 15(4): 315-322.
doi: 10.1089/dia.2012.0259 URL |
[24] |
Bacha F, Pyle L, Nadeau K, et al. Determinants of glycemic control in youth with type 2 diabetes at randomization in the TODAY study[J]. Pediatr Diabetes, 2012, 13(5): 376-383.
doi: 10.1111/j.1399-5448.2011.00841.x pmid: 22332798 |
[25] |
TODAY Study Group. Effects of metformin, metformin plus rosiglitazone, and metformin plus lifestyle on insulin sensitivity and β-cell function in TODAY[J]. Diabetes Care, 2013, 36(6): 1749-1757.
doi: 10.2337/dc12-2393 URL |
[26] |
TODAY Study Group. Postintervention effects of varying treatment arms on glycemic failure and β-cell function in the today trial[J]. Diabetes Care, 2021, 44(1): 75-80.
doi: 10.2337/dc20-0622 URL |
[27] |
Šrámek J, Němcová-Fürstová V, Kovář. Molecular mechanisms of apoptosis induction and its regulation by fatty acids in pancreatic β-cells[J]. Int J Mol Sci, 2021, 22(8):4285.
doi: 10.3390/ijms22084285 URL |
[28] | Ding Y, Yang GY, Wu Q. Autophagic dysfunction of β cell dysfunction in type 2 diabetes, a double-edged sword[J]. Genes Dis, 2020, 8(4): 438-447. |
[29] | Bensellam M, Jonas JC, Laybutt DR. Mechanisms of β-cell dedifferentiation in diabetes: recent findings and future research directions[J]. J Endocrinol, 2018, 236(2): R109-R143. |
[30] |
Lee EY, Yoon KH. Epidemic obesity in children and adolescents: risk factors and prevention[J]. Front Med, 2018, 12(6): 658-666.
doi: 10.1007/s11684-018-0640-1 URL |
[31] |
Twig G, Zucker I, Afek A, et al. Adolescent obesity and early-onset type 2 diabetes[J]. Diabetes Care, 2020, 43(7): 1487-1495.
doi: 10.2337/dc19-1988 URL |
[32] | Ahmed B, Sultana R, Greene MW. Adipose tissue and insulin resistance in obese[J]. Biomed Pharmacother, 2021, 137: 111315. |
[33] |
Tagi VM, Chiarelli F. Obesity and insulin resistance in children[J]. Curr Opin Pediatr, 2020, 32(4): 582-588.
doi: 10.1097/MOP.0000000000000913 URL |
[34] | 曹晶珠, 王元辰, 洪惠兰, 等. 不同体质指数早发2型糖尿病的临床特征分析[J]. 中国临床医学, 2019, 26(1): 14-18. |
[35] | Hao Z, Huang X, Liu X, et al. Association analysis between different diabetic family history and gender with diagnosed age of type 2 diabetes mellitus: a cross-sectional study in Tianjin, China[J]. Inquiry, 2022, 59: 4695 80221086364. |
[36] |
Piko P, Werissa NA, Fiatal S, et al. Impact of genetic factors on the age of onset for type 2 diabetes mellitus in addition to the conventional risk aactors[J]. J Pers Med, 2020, 11(1): 6.
doi: 10.3390/jpm11010006 URL |
[37] | Kong X, Xing X, Zhang X, et al. Early-onset type 2 diabetes is associated with genetic variants of β-cell function in the Chinese Han population[J]. Diabetes Metab Res Rev, 2020, 36(2): e3214. |
[38] | Norris SA, Daar A, Balasubramanian D, et al. Understanding and acting on the developmental origins of health and disease in Africa would improve health across generations[J]. Glob Health Action, 2017, 10(1): 1334985. |
[39] |
Tam CHT, Ma RCW, Yuen LY, et al. The impact of maternal gestational weight gain on cardiometabolic risk factors in children[J]. Diabetologia, 2018, 61(12): 2539-2548.
doi: 10.1007/s00125-018-4724-x URL |
[40] |
Kadayifci FZ, Haggard S, Jeon S, et al. Early-life programming of type 2 diabetes mellitus: understanding the association between epigenetics/genetics and environmental factors[J]. Curr Genomics, 2019, 20(6): 453-463.
doi: 10.2174/1389202920666191009110724 pmid: 32477001 |
[41] | 周丽媛, 肖新华. 生命早期营养与糖代谢异常发生发展的新启示:糖尿病防治窗口需前移[J]. 中华糖尿病杂志, 2021, 13(12): 1109-1114. |
[42] | Isganaitis EM, Shah R, Chernausek S, et al. 19-Or: maternal diabetes is associated with adverse diabetes characteristics and accelerated onset of complications in youth with type 2 diabetes (t2d) in today[J]. 2021, 70 Suppl 1: 19-OR. |
[43] | 牛海芳. 早发2型糖尿病患者发病的危险因素及其在不同性别间的差异[J]. 广西医学, 2020, 42(14): 1804-1807. |
[44] | Park JI, Baek H, Kim SW, et al. Questionnaire-based survey of demographic and clinical characteristics, health behaviors, and mental health of young Korean adults with early-onset diabetes[J]. J Korean Med Sci, 2021, 36(26): e182. |
[45] |
Fiore V, Marci M, Poggi A, et al. The association between diabetes and depression: a very disabling condition[J]. Endocrine, 2015, 48(1): 14-24.
doi: 10.1007/s12020-014-0323-x URL |
[46] | Li FF, Liu BL, Yin GP, et al. Young onset type 2 diabetic patients might be more sensitive to metformin compared to late onset type 2 diabetic patients[J]. Sci Rep, 2017, 7(1): 16382. |
[47] |
Matthews DR, Paldánius PM, Proot P, et al. Glycaemic durability of an early combination therapy with vildagliptin and metformin versus sequential metformin monotherapy in newly diagnosed type 2 diabetes (VERIFY): a 5-year, multicentre, randomised, double-blind trial[J]. Lancet, 2019, 394(10208): 1519-1529.
doi: S0140-6736(19)32131-2 pmid: 31542292 |
[48] |
Pan J, Jia W. Early-onset diabetes: an epidemic in China[J]. Front Med, 2018, 12(6): 624-633.
doi: 10.1007/s11684-018-0669-1 URL |
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