Journal of Surgery Concepts & Practice ›› 2023, Vol. 28 ›› Issue (06): 563-567.doi: 10.16139/j.1007-9610.2023.06.013
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HE Xi, SHI Yuan, QIAN Kai, WANG Zhuoying
Received:
2023-11-13
Online:
2023-11-25
Published:
2024-03-04
CLC Number:
HE Xi, SHI Yuan, QIAN Kai, WANG Zhuoying. Advances of protein lysine methyltransferases in thyroid carcinoma[J]. Journal of Surgery Concepts & Practice, 2023, 28(06): 563-567.
[1] |
SUNG H, FERLAY J, SIEGEL R L, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J]. CA Cancer J Clin, 2021, 71(3):209-249.
doi: 10.3322/caac.v71.3 URL |
[2] |
ZHENG R S, ZHANG S W, ZENG HW, et al. Cancer incidence and mortality in China, 2016[J]. J National Cancer Center, 2022, 2(1):1-9.
doi: 10.1016/j.jncc.2022.02.002 URL |
[3] |
DAWSON M A, KOUZARIDES T. Cancer epigenetics: from mechanism to therapy[J]. Cell, 2012, 150(1):12-27.
doi: 10.1016/j.cell.2012.06.013 pmid: 22770212 |
[4] |
BHATTACHARYYA S, MATTIROLI F, LUGER K. Archaeal DNA on the histone merry-go-round[J]. FEBS J, 2018, 285(17):3168-3174.
doi: 10.1111/febs.14495 pmid: 29729078 |
[5] |
BAE W K, HENNIGHAUSEN L. Canonical and non-canonical roles of the histone methyltransferase EZH2 in mammary development and cancer[J]. Mol Cell Endocrinol, 2014, 382(1):593-597.
doi: S0303-7207(13)00205-0 pmid: 23684884 |
[6] |
BORBONE E, TRONCONE G, FERRARO A, et al. Enhancer of zeste homolog 2 overexpression has a role in the development of anaplastic thyroid carcinomas[J]. J Clin Endocrinol Metab, 2011, 96(4):1029-1038.
doi: 10.1210/jc.2010-1784 pmid: 21289264 |
[7] |
GUO K, QIAN K, SHI Y, et al. LncRNA-MIAT promotes thyroid cancer progression and function as ceRNA to target EZH2 by sponging miR-150-5p[J]. Cell Death Dis, 2021, 12(12):1097.
doi: 10.1038/s41419-021-04386-0 pmid: 34811354 |
[8] |
XUE L, YAN H, CHEN Y, et al. EZH2 upregulation by ERα induces proliferation and migration of papillary thyroid carcinoma[J]. BMC Cancer, 2019, 19(1):1094.
doi: 10.1186/s12885-019-6306-9 pmid: 31718595 |
[9] |
SPONZIELLO M, DURANTE C, BOICHARD A, et al. Epigenetic-related gene expression profile in medullary thyroid cancer revealed the overexpression of the histone methyltransferases EZH2 and SMYD3 in aggressive tumours[J]. Mol Cell Endocrinol, 2014, 392(1-2):8-13.
doi: 10.1016/j.mce.2014.04.016 pmid: 24813658 |
[10] |
TSAI C C, CHIEN M N, CHANG Y C, et al. Overexpression of histone H3 lysine 27 trimethylation is associated with aggressiveness and dedifferentiation of thyroid cancer[J]. Endocr Pathol, 2019, 30(4):305-311.
doi: 10.1007/s12022-019-09586-1 |
[11] |
WANG Z, DAI J, YAN J, et al. Targeting EZH2 as a novel therapeutic strategy for sorafenib-resistant thyroid carcinoma[J]. J Cell Mol Med, 2019, 23(7):4770-4778.
doi: 10.1111/jcmm.14365 pmid: 31087496 |
[12] |
DE MELLO D C, SAITO K C, CRISTOVÃO M M, et al. Modulation of EZH2 activity induces an antitumoral effect and cell redifferentiation in anaplastic thyroid cancer[J]. Int J Mol Sci, 2023, 24(9):7872.
doi: 10.3390/ijms24097872 URL |
[13] | 梁碧君, 李湘平, 鲁娟, 等. EZH2对鼻咽癌细胞增殖和侵袭影响的研究[J]. 中华耳鼻咽喉头颈外科杂志, 2012, 47(4):298-304. |
LIANG B J, LI X P, LU J, et al. Study on the effect of EZH2 on the proliferation and invasion of nasopharyngeal cancer cells[J]. Chin J Otorhinolaryngol Head Neck Surg, 2012, 47(4):298-304. | |
[14] | SI Y, WEN J, HU C, et al. LINC00891 promotes tumorigenesis and metastasis of thyroid cancer by regulating SMAD2/3 via EZH2[J]. Curr Med Chem, 2023. |
[15] | DE MARTINO M, PELLECCHIA S, DECAUSSIN-PETRUCCI M, et al. Drug-induced inhibition of HMGA and EZH2 activity as a possible therapy for anaplastic thyroid carcinoma[J]. Cell Cycle, 2024:1-14. |
[16] | ZHANG C, HUA Y, QIU H, et al. KMT2A regulates cervical cancer cell growth through targeting VDAC1[J]. Aging (Albany NY), 2020, 12(10):9604-9620. |
[17] |
ZHAO D, YUAN H, FANG Y, et al. Histone methyltransferase KMT2B promotes metastasis and angiogenesis of cervical cancer by upregulating EGF expression[J]. Int J Biol Sci, 2023, 19(1):34-49.
doi: 10.7150/ijbs.72381 pmid: 36594087 |
[18] |
FENG J F, WANG J, XIE G, et al. KMT2B promotes the growth of renal cell carcinoma via upregulation of SNHG12 expression and promotion of CEP55 transcription[J]. Cancer Cell Int, 2022, 22(1):197.
doi: 10.1186/s12935-022-02607-w |
[19] |
SIERRA J, YOSHIDA T, JOAZEIRO C A, et al. The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes[J]. Genes Dev, 2006, 20(5):586-600.
doi: 10.1101/gad.1385806 URL |
[20] |
COLAMAIO M, PUCA F, RAGOZZINO E, et al. MiR-142-3p down-regulation contributes to thyroid follicular tumorigenesis by targeting ASH1L and MLL1[J]. J Clin Endocrinol Metab, 2015, 100(1):E59-E69.
doi: 10.1210/jc.2014-2280 URL |
[21] |
FAGAN R J, DINGWALL A K. COMPASS ascending: emerging clues regarding the roles of MLL3/KMT2C and MLL2/KMT2D proteins in cancer[J]. Cancer Lett, 2019, 458:56-65.
doi: S0304-3835(19)30319-2 pmid: 31128216 |
[22] |
NA F, PAN X, CHEN J, et al. KMT2C deficiency promotes small cell lung cancer metastasis through DNMT3A-mediated epigenetic reprogramming[J]. Nat Cancer, 2022, 3(6):753-767.
doi: 10.1038/s43018-022-00361-6 |
[23] |
ALAM H, TANG M, MAITITUOHETI M, et al. KMT2D deficiency impairs super-enhancers to confer a glycolytic vulnerability in lung cancer[J]. Cancer Cell, 2020, 37(4):599-617.e7.
doi: S1535-6108(20)30106-9 pmid: 32243837 |
[24] |
CHO S J, YOON C, LEE J H, et al. KMT2C mutations in diffuse-type gastric adenocarcinoma promote epithelial-to-mesenchymal transition[J]. Clin Cancer Res, 2018, 24(24):6556-6569.
doi: 10.1158/1078-0432.CCR-17-1679 URL |
[25] |
NIEMINEN T T, WALKER C J, OLKINUORA A, et al. Thyroid carcinomas that occur in familial adenomatous polyposis patients recurrently harbor somatic variants in APC, BRAF, and KTM2D[J]. Thyroid, 2020, 30(3):380-388.
doi: 10.1089/thy.2019.0561 URL |
[26] |
SONG J, LIU Y, CHEN Q, et al. Expression patterns and the prognostic value of the SMYD family members in human breast carcinoma using integrative bioinformatics analysis[J]. Oncol Lett, 2019, 17(4):3851-3861.
doi: 10.3892/ol.2019.10054 pmid: 30930987 |
[27] |
KOMATSU S, ICHIKAWA D, HIRAJIMA S, et al. Overexpression of SMYD2 contributes to malignant outcome in gastric cancer[J]. Br J Cancer, 2015, 112(2):357-364.
doi: 10.1038/bjc.2014.543 |
[28] |
XU W, CHEN F, FEI X, et al. Overexpression of SET and MYND domain-containing protein 2 (SMYD2) is associated with tumor progression and poor prognosis in patients with papillary thyroid carcinoma[J]. Med Sci Monit, 2018, 24:7357-7365.
doi: 10.12659/MSM.910168 URL |
[29] |
HUANG J, PEREZ-BURGOS L, PLACEK B J, et al. Repression of p53 activity by Smyd2-mediated methylation[J]. Nature, 2006, 444(7119):629-632.
doi: 10.1038/nature05287 |
[30] |
TANG M, CHEN G, TU B, et al. SMYD2 inhibition-mediated hypomethylation of Ku70 contributes to impaired nonhomologous end joining repair and antitumor immunity[J]. Sci Adv, 2023, 9(24):eade6624.
doi: 10.1126/sciadv.ade6624 URL |
[31] |
HAMAMOTO R, SILVA F P, TSUGE M, et al. Enhanced SMYD3 expression is essential for the growth of breast cancer cells[J]. Cancer Sci, 2006, 97(2):113-118.
doi: 10.1111/cas.2006.97.issue-2 URL |
[32] |
ZHU Y, ZHU M X, ZHANG X D, et al. SMYD3 stimulates EZR and LOXL2 transcription to enhance proliferation, migration, and invasion in esophageal squamous cell carcinoma[J]. Hum Pathol, 2016, 52:153-163.
doi: 10.1016/j.humpath.2016.01.012 pmid: 26980013 |
[33] |
KUNIZAKI M, HAMAMOTO R, SILVA F P, et al. The lysine 831 of vascular endothelial growth factor receptor 1 is a novel target of methylation by SMYD3[J]. Cancer Res, 2007, 67(22):10759-10765.
doi: 10.1158/0008-5472.CAN-07-1132 pmid: 18006819 |
[34] |
RUBIO-TOMÁS T. Novel insights into SMYD2 and SMYD3 inhibitors: from potential anti-tumoural therapy to a variety of new applications[J]. Mol Biol Rep, 2021, 48(11):7499-7508.
doi: 10.1007/s11033-021-06701-6 |
[35] |
SHANG L, WEI M. Inhibition of SMYD2 sensitized cisplatin to resistant cells in NSCLC through activating p53 pathway[J]. Front Oncol, 2019, 9:306.
doi: 10.3389/fonc.2019.00306 pmid: 31106145 |
[36] |
FAN Y, FAN X, YAN H, et al. Long non-coding ROR promotes the progression of papillary thyroid carcinoma through regulation of the TESC/ALDH1A1/TUBB3/PTEN axis[J]. Cell Death Dis, 2022, 13(2):157.
doi: 10.1038/s41419-021-04210-9 pmid: 35173149 |
[37] | LIAO T, WANG Y J, HU J Q, et al. Histone methyltransferase KMT5A gene modulates oncogenesis and lipid metabolism of papillary thyroid cancer in vitro[J]. Oncol Rep, 2018, 39(5):2185-2192. |
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