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    25 May 2020, Volume 25 Issue 03 Previous Issue    Next Issue
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    Editorial
    Current status and development of laparoscopic techniques and platform
    ZHENG Minhua, MA Junjun
    2020, 25 (03):  181-183.  DOI: 10.16139/j.1007-9610.2020.03.001
    Abstract ( 457 )   HTML ( 9 )   PDF (433KB) ( 227 )  
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    Experts forum
    Status and development of minimally invasive treatment for colorectal surgery
    YANG Yingchi, WANG Yang, ZHANG Zhongtao
    2020, 25 (03):  184-188.  DOI: 10.16139/j.1007-9610.2020.03.002
    Abstract ( 308 )   HTML ( 2 )   PDF (672KB) ( 70 )  
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    Laparoscopic and robotic surgery in treatment of early and advanced gastric cancer
    ZHANG Chi, HU Xiang
    2020, 25 (03):  189-194.  DOI: 10.16139/j.1007-9610.2020.03.003
    Abstract ( 340 )   HTML ( 1 )   PDF (584KB) ( 80 )  
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    Selection of bariatric metabolic surgery
    WANG Cunchuan, ZHAO Xin, YANG Hua
    2020, 25 (03):  195-197.  DOI: 10.16139/j.1007-9610.2020.03.004
    Abstract ( 328 )   HTML ( 1 )   PDF (353KB) ( 190 )  
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    Status and development of endoscopic and laparoscopic treatment of gastric cancer
    ZHANG Shaopeng, LI Wei, SUO Jian
    2020, 25 (03):  202-206.  DOI: 10.16139/j.1007-9610.2020.03.006
    Abstract ( 299 )   HTML ( 1 )   PDF (537KB) ( 85 )  
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    Guideline and consensus
    Original article
    A retrospective study on laparoscopic complete mesocolic excision via dorsal-medial hybrid approach for right colon cancer
    LIU Haishan, CAI Zhenghao, MA Junjun, SUN Jing, HE Zirui, ZANG Lu, DONG Feng, FENG Bo, ZONG Yaping, XUE Pei, ZHANG Luyang, LU Aiguo, ZHENG Minhua
    2020, 25 (03):  211-216.  DOI: 10.16139/j.1007-9610.2020.03.008
    Abstract ( 412 )   HTML ( 1 )   PDF (1157KB) ( 122 )  

    Objective To investigate pathologic effects combined with postoperative results on right colon cancer with laparoscopic complete mesocolic excision(CME) via dorsal-medial hybrid approach compared with traditional medial approach. Methods A total of 68 patients with right colon cancer undergoing laparoscopic CME in our hospital between Ja-nuary and June 2017 were studied retrospectively. There were two groups including 37 cases in dorsal-medial hybrid group and 31 cases in traditional medial group. CME quality evaluated with the method proposed by West et al along with safety, short-term results and long-term prognosis were compared between two groups. Results CME completion rate was 86.5% in dorsal-medial hybrid group and 80.6% in traditional medial group without statistical difference(P=0.53). Laparoscopic dissection time in dorsal-medial group was significantly shorter than that in traditional medial group[(62.70±12.22) min vs.(70.39±11.98) min, P=0.01]. There was no statistical difference in operation time, blood loss, postoperative flatus time, postoperative complications and long-term prognosis of the patients between two groups. Conclusions Laparoscopic CME via dorsal-medial hybrid approach for right colon cancer could have less laparoscopic dissection time, and two approaches were similar in CME quality, safety and prognosis.

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    Analysis of risk factors for lymph node groups 5 and 6 metastasis in gastric cancer
    WANG Zihao, CAO Liang, LIANG Pin, LIU Ge, ZHANG Chi, ZHANG Jian, YIN Xunguo, LIU Huanran, LIU Yanfeng, HU Xiang
    2020, 25 (03):  217-221.  DOI: 10.16139/j.1007-9610.2020.03.009
    Abstract ( 740 )   HTML ( 2 )   PDF (566KB) ( 124 )  

    Objective To analyze the correlation of both the distance from lower edge of gastric cancer to pylorus and the Borrmann classification with metastasis of lymph node groups (LNG) 5 (suprapyloric) and 6 (infrapyloric). Methods There were 374 cases with gastric cancer including the group with LNG 5 and 6 metastasis and the group without LNG 5 and 6 metastasis. The critical ditance from lower edge of gastric cancer to pylorus which predicted LNG 5 and 6 metastasis was analyzed combined with the risk factors for LNG 5 and 6 metastasis. LNG 5 and 6 metastasis in patients with gastric cancer stage T1 and T2 (Borrmann Ⅱ) was analyzed. Results LNG 5 and 6 metastasis in patients with gastric cancer could be predicted using distance from lower edge of tumor to pylorus with the critical distance 3.75 cm. The rate of lymph node metastasis was 11.1% when the distance from lower edge to pylorus was longer than 3.75 cm. The independent risk factors for LNG 5 and 6 metastasis were gotten including the distance from the lower edge of tumor to pylorus, Borrmann classification, extent of differentiation of cancer, depth of infiltration, and gastric cancer stage. There was no statistical difference in metastasis of LNG 5 and 6 between stage T1 and stage T2 (Borrmann Ⅱ) of gastric cancer when the distance from lower edge of tumor to pylorus was longer than 3.75 cm (P>0.05). Conclusions There was no difference in LNG 5 and 6 metastasis between T1 and T2 (Borrmann Ⅱ) gastric cancer, when the distance from lower edge of tumor to pylorus was longer than 3.75 cm,

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    Splenic artery embolization versus surgery in treatment of traumatic splenic injury: a comparative study
    ZHANG Lipeng, WANG Zhongmin, ZHAO Xinjian
    2020, 25 (03):  222-226.  DOI: 10.16139/j.1007-9610.2020.03.010
    Abstract ( 410 )   HTML ( 4 )   PDF (775KB) ( 120 )  

    Objective To compare the clinical effect between splenic artery interventional embolization and surgery in the management of patients with traumatic splenic injury. Methods Forty patients with traumatic splenic injury in the First Affiliated Hospital, Shihezi University Medical College from 2014 to 2018 were studied for comparison, 20 cases with splenic artery embolization and 20 cases with surgery as control group. The index were evaluated including the efficacy of interventional therapy, postoperative blood pressure, account of blood cells, procedure duration, blood loss, hospital stay and postoperative complications. Results All patients in splenic artery interventional embolization group were successfully treated. Reduced procedure duration, less blood loss, less time of hospitalization and less cases with postoperative complications were found significantly (P<0.05) when compared with those in control group. Conclusions Splenic artery interventional embolization was safe and effective in the treatment of patients with traumatic splenic injury.

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    Study on microRNA-9-5p reducing sensitivity of breast cancer cells to doxorubicin through targeting HIC1
    GAO Hang, ZHAO Feng, WU Yan, PEI Wenjiang, ZHONG Ming, GU Yan, GUO Shanyu, DAI Qiancheng, ZHANG Wei
    2020, 25 (03):  227-233.  DOI: 10.16139/j.1007-9610.2020.03.011
    Abstract ( 367 )   HTML ( 1 )   PDF (1125KB) ( 66 )  

    Objective To study the effect of microRNA-9-5p (miR-9-5p) which regulate hypermethylated in cancer 1 (HIC1) in reducing sensitivity of breast cancer MDA-MB-231 cells to doxorubicin (DOX) and the mechanisms. Methods ①Up-regulation or down-regulation of miR-9-5p in cells was constructed by lentivirus transfection. Cell viability and apoptosis were detected with CCK-8 and flow cytometry after adding different concentrations of DOC. ②Expression of HIC1 was detected by reverse transcription-polymerase chain reaction and Western blotting when miRNA-9-5p was overexpressed or inhibited. The interaction between miR-9-5p and HIC1 was analyzed by database and luciferase assay. ③HIC1 was down-regulated to detect cell viability and apoptosis after adding different concentrations of DOX. Results ①Up-regulation of miR-9-5p increased cell viability, and reduced apoptosis. Down-regulation of miR-9-5p reduced cell viability and increased apoptosis. ②miR-9-5p directly targeted HIC1 and negative relationship of expression was present between miR-9-5p and HIC1. ③Down-regulation of HIC1 could reverse the down-regulation effect of miR-9-5p. Conclusions miR-9-5p reduces the sensitivity of breast cancer cells to DOX through down-regulation of HIC1.

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    Application of Tider process in parathyroidectomy for treatment of secondary hyperparathyroidism
    SHAN Chengxiang, LI Wei, LIU Bingyang, WANG Qiang, RAO WenSheng, ZHA Siluo, QIU Ming, ZHANG Wei
    2020, 25 (03):  234-238.  DOI: 10.16139/j.1007-9610.2020.03.012
    Abstract ( 474 )   HTML ( 2 )   PDF (607KB) ( 97 )  

    Objective To optimize the operative process of parathyroidectomy (PTX) for the treatment of secondary hyperparathyroidism (SHPT). Methods Four approaches including tracing/imaging, dissection, exploration, and resection were integrated into Tider process. Nano-carbon particles were used to inject into thyroid glands for imaging and separation of cervical tissue was performed with specific vision of anatomic landmarks. Parathyroid glands were thoroughly revealed by standard exploration using inspection and palpation. Resection of parathyroids should involve the surrounding tissue as more as possible. This Tider process was used into PTX for 25 patients with SHPT in Tider group since March 2018. Thirty-four patients with SHPT without use of Tider process were in control group from March 2015 to December 2018. Outcomes including operative time, operative success rate and PTH at the postoperative first day were compared between Tider group and control group. Results Total PTX and total PTX with auto-transplantation in Tider group were all done successfully in 22 cases and 3 cases, respectively. A total of 101 parathyroid were resected with maximum diameter (1.56±0.63) cm of left superior gland, (1.66±0.53) cm of left inferior gland, (1.51±0.56) cm of right superior gland, and (1.72±0.76) cm of right inferior gland. Operative time ranged from 60 to 150 min with less time [(82.8±9.5) min] in Tider group than that [(98.5±20.4) min] in control group significantly (P=0.001). No operative complications such as bleeding, recurrent laryngeal nerve injury and severe hypocalcemia were found in both groups except one case died due to suffocation after tracheal extubation in control group. PTH in Tider group was (22.9±10.3) ng/L (<65 ng/L) at the postoperative first day. However, operation failed 6 cases in control group with PTH (112.3±239.6) (7.7~1 216.0) ng/L at the postoperative first day. Operative success in control group was 82.4% with no difference in success rate between 2 groups (P=0.075). Conclusions Tider process could be useful in PTX procedure with less operative time, more standardization and successful operation.

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    Analysis of risk factors of wound complication after emergent surgery via a midline vertical incision
    YU Ping, WANG Yue, ZHAI Shuyu, WANG Xiaoyan, HUANG Liang, MAO Enqiang
    2020, 25 (03):  239-244.  DOI: 10.16139/j.1007-9610.2020.03.013
    Abstract ( 463 )   HTML ( 2 )   PDF (760KB) ( 52 )  

    Objective To establish the nomogram and predict the risk factors of wound complication in patients with emergent abdominal surgery via a midline vertical incision. Methods The clinical data of 247 patients treated in Department of Surgery Ruijin Hospital including 68 cases with wound complication and 139 cases without wound complication were collected and analyzed. Risk predictors were selected from the items of clinical strategies by the least absolute shrinkage and selection operator (LASSO) regression model and multivariable logistic regression analysis was performed with incorporated items. C-index and calibration plot were used to evaluate the discrimination and calibration of prediction model. Results Six items including age ≥60 years, smoking and history of abdominal surgery, preoperative lower albumin in serum and increase in C-reactive protein level, and both continuous and interrupted suture of abdominal incision were included in the prediction model. The prediction model showed better discrimination and calibration with a C-index of 0.747 (95%Cl: 0.678-0.816). Conclusions The established nomogram can be used to predict the risk of wound complication in patients with emergent abdominal surgery via abdominal midline vertical incision.

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    Effect of robotic surgery on urinary function following radical resection for middle and low rectal cancer: a propensity score matching analysis
    ZHANG Yaqi, ZHANG Tao, SONG Zijia, GU Yifei, PENG Yi, JI Xiaopin, ZHAO Ren
    2020, 25 (03):  245-251.  DOI: 10.16139/j.1007-9610.2020.03.014
    Abstract ( 399 )   HTML ( 0 )   PDF (738KB) ( 68 )  

    Objective To compare perioperative index and postoperative urinary function following radical resection for middle and low rectal cancer between robotic and laparoscopic surgery. Methods Clinicopathological data of 313 patients with radical surgery for middle and low rectal cancer at our department from September 2015 to October 2018 were analyzed retrospectively. Propensity score matching analysis (1∶1, caliper value=0.01) between robotic surgery group and laparoscopic surgery group was performed based on gender, age, body mass index, American Society of Anesthesiology score, and tumor staging. Two surgical approaches were studied for safety in radical treatment of middle and low rectal cancer and the effect on urinary function, which was assessed using the International Prostate Symptom Score (IPSS) preope-ratively and 1, 3, and 6 months after surgery. Results The matched sample of 101 cases in two groups using propensity score was included. There was no statistical difference in the outcome of radical resection between two groups. However, significant differences were found in operative time, intraoperative blood loss, time to first flatus and postoperative hospital stay (P<0.001). IPSS of robotic surgery group was significantly lower than that of laparoscopic group 1 month after surgery(P<0.001). IPSS of patients older than 60 with low rectal cancer in robotic surgery group was lower than that in laparoscopic surgery group 1 month postoperatively(P=0.027), and no significant difference in IPSS 3 and 6 months after surgery was present between two groups. Conclusions The efficacy of robotic radical surgery was same as laparoscopic surgery for middle and low rectal cancer. The radical surgery of patients with rectal cancer in robotic approach had urinary function less impaired and short-term rehabilitation better compared to that in laparoscopic approach, especially for patients older than 60 with low rectal cancer.

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    Effect of enhanced recovery after surgery on thyroid surgery
    ZHENG Lei, ZHANG Shiyu, YAN Jiqi
    2020, 25 (03):  252-255.  DOI: 10.16139/j.1007-9610.2020.03.015
    Abstract ( 368 )   HTML ( 3 )   PDF (483KB) ( 77 )  

    Objective To evaluate the effects of enhanced recovery after surgery (ERAS) for thyroid surgery throughout the perioperative period. Methods A total of 120 cases with thyroid surgery in our hospital from March to June 2018 were divided into ERAS group and traditional group with 60 cases each. Pain scores after surgery, postoperative complications, length of hospital stay and costs were compared between two groups. Results The pain scores (2.2 vs. 2.8), length of hospital stay (1.0 d vs. 3.4 d) and costs (10 204.8 Yuan vs. 12 449.2 Yuan) in ERAS group were less than those in traditional group (P<0.001). There was no statistical difference in postoperative complications rate between two groups. Conclusions It could be found that ERAS helped to decrease length of hospital stay and reduce cost while improve postoperative pain control.

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    Clinical research
    Clinical experience of enterocutaneous fistula: a report of 43 cases
    ZHOU Haihua, ZHANG Bo, WANG Jianqiu
    2020, 25 (03):  256-258.  DOI: 10.16139/j.1007-9610.2020.03.016
    Abstract ( 396 )   HTML ( 0 )   PDF (454KB) ( 76 )  
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    A comparative study of wound infiltration analgesia after minimally invasive hernia repair between ketorolac tromethamine and levobupivacaine
    WANG Dan, NI Yanting, WU Dejun, CUI Peng, XU Ming, MIN Zhijun, WANG Tingfeng
    2020, 25 (03):  259-262.  DOI: 10.16139/j.1007-9610.2020.03.017
    Abstract ( 442 )   HTML ( 2 )   PDF (659KB) ( 90 )  
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    Review
    Outcomes of bariatric surgery in obese patients with Prader-Willi syndrome
    CHEN Guoji, YANG Hua, WANG Cunchuan
    2020, 25 (03):  263-268.  DOI: 10.16139/j.1007-9610.2020.03.018
    Abstract ( 389 )   HTML ( 3 )   PDF (691KB) ( 60 )  
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