Abstract: Objective To investigate the risk factors for disseminated intravascular coagulation (DIC) after operation of multiple fractures. Methods Patients with multiple fractures combined with DIC from March 2017 to December 2018 were enrolled as experimental groups. According to the gender and age, patients with multiple fractures with the same sample size in the same time period but without DIC were matched as the control group. Analysis of the number of fractures, smoking history, hyperlipidemia, and platelet, prothrombin time, international normalized ratio, D-dimer, homocysteine on the first day after operation were evaluated for predicting DIC. Results Finally, 48 cases were included in the experimental group and 48 cases in the control group. According to the binary logistic regression analysis, it was found that platelets, D-dimer and homocysteine on the first day after operation were the risk factors for DIC. The above indicators were used to draw ROC curves. It was found that D-dimer and homocysteine on the first day after operation were the independent risk factors for DIC. Conclusion For patients with multiple fractures, if the D-dimer and homocysteine values are higher on the first day after operation, it is necessary to be alert to the possibility of DIC.

Key words: Multiple fractures, Disseminated intravascular coagulation, Risk factors