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Table of Content

    23 July 2020, Volume 9 Issue 6 Previous Issue    Next Issue
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    Original article
    Histological Observation of Autogenous Bone Dust Grafting and Membrane Guided Regeneration Technology to Repair Skull Defects
    CHEN Minjian,LU Ting,CHEN Ping
    2013, 9 (6):  311-314.  DOI: 10.3969/j.issn.1673-0364.2013.06.003
    Abstract ( 359 )  
    Objective To repair the skull defects by using autogenous skull bone dust grafting and membrane guided regeneration technology, and to investigate its histological evolution. Methods Fifty New Zealand white rabbits were selected. A whole thick defect with the diameter of 1 cm was created in the parietal bone of every rabbit. The defect was grafted with autogenous skull bone dust and two pieces of absorbable membrane on two side. After 2, 4, 6, 8, 12 weeks, the defects were harvested for histological observation. Results Two weeks after operation, a large number of bone meal was observed in the defect area. Inward infiltration of inflammatory cells, capillaries and fibroblasts were observed. Bone meal was swallowed in the central area, new bone was formed in the surrounding area and a clear boundary was observed between the two area. Four weeks after operation, the boundary had moved a lot to the central area. New woven bone was thickened, the connection between the woven bone became more closely. Tissue and cell components had no obvious change compared with 2 weeks after operation. Six weeks after operation, bone meal was almost absorbed, the woven bone became thicker and the connection was more closely. Eight weeks after operation, no bone dust could be observed, a monolayer new bone was formed in the central area. The woven bone in the surrounding area was relatively thick and closely connected with normal bone. The primary bone marrow cavity was formed. Twelve weeks after operation, double new bone was observed in the central area. New bone remodeling and mature bone marrow cavity were also observed. The morphology and composition of bone marrow cavity had no difference compared with normal bone. Conclusion Histological evolution of autogenous bone dust grafting and membrane guided regeneration technology to repair skull defects is guided and induced bone regeneration.
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    Minimally Invasive Percutaneous Plate Internal Fixation in Tibia Fractures of Distal 1/3
    ZHENG Yong,SHI Fajian,ZHAO Xiaolong
    2013, 9 (6):  334-353.  DOI: 10.3969/j.issn.1673-0364.2013.06.009
    Abstract ( 376 )  
    Objective To investigate the clinical effect of minimally invasive percutaneous plate internal fixation in tibia fractures of distal 1/3. Methods From April 2011 to April 2013, 29 cases with tibia fractures of distal 1/3 were treated with minimally invasive percutaneous plate internal fixation. The situation of operation, the fracture healing, postoperative Johner-Wruh score, patient satisfaction after operation and the incidence of adverse reactions were evaluated. Results All the patients were followed up for (11.2 ±0.8) months. In the 29 cases, the average operation time was (70.7 ±12.5) min and the average bleeding quantity was (157.3±16.4) ml. The average radiographic healing time was (14.7±2.6) weeks and full weight-bearing time averaged (15.2±3.1) weeks. Johner-Wruh score of patients increased significantly after surgery (P<0.05). The average postoperative satisfaction score was (93.4±2.1). One case of adverse reaction was observed. Conclusion Minimally invasive percutaneous plate osteosynthesis is an effective method for the treatment of tibia fractures of distal 1/3.
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    Effect of Interscalene Nerve Block Adding Opioid Analgesics on Postoperative Analgesia
    LU Jun,YANG Jun,SHEN Yan
    2013, 9 (6):  342-343.  DOI: 10.3969/j.issn.1673-0364.2013.06.012
    Abstract ( 358 )  
    Objective To investigate the effect of interscalene nerve block adding opioid analgesics on postoperative analgesia for upper extremity surgery. Methods Interscalene nerve block with tramadol or fentanyl added respectively was given to the patients for the anesthesia of upper extremity surgery. The analgesic effect was observed and evaluated after surgery. Results Analgesic effect in experimental groups adding opioid analgesics was better than in control group ( P<0.05). Conclusion Adding opioid analgesic drugs to interscalene nerve block can reach a better postoperative analgesia effect.
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    Research Progress on Markers of Infantile Hemangioma
    MA Gang,LIN Xiaoxi
    2013, 9 (6):  344-348.  DOI: 10.3969/j.issn.1673-0364.2013.06.013
    Abstract ( 411 )  
    Infantile hemangioma (IH) is the most common benign tumor in childhood, which has unique natural history with early proliferation and spontaneous involution courses. However its pathogenesis has not been elucidated, especially its specific biomarkers. In this paper, the research progress of this aspect was reviewed. Histologic biomarkers were consist of angiogenesis, placenta, apoptosis, hypoxia, inflammation, lymphatic, stem cell, pericyte and mast cell associated markers. Humoral biomarkers contained serum and urine markers, the former mainly had the cytokines such as estrogen and VEGF, the latter included bFGF and MMP-2. But so far there were not serum markers found to be closely related to the course of IH with strong sensitivity and specificity.
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    Research Progress of Ureteral Replacement
    FAN Kangwu
    2013, 9 (6):  354-356.  DOI: 10.3969/j.issn.1673-0364.2013.06.015
    Abstract ( 445 )  
    To seek a suitable replacement material for the treatment of long segment defect of ureter, has always been one of the hot topics in the field of clinical urology. At present the replacement materials mainly include: intestine (ileum, appendix), vein, omentum majus, bladder-renal pelvis flap and tissue engineering materials. In this paper, the advantages and disadvantages of all kinds of ureteral replacement materials and the latest research progress were reviewed.
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    Research Progress of Flaps for the Repair of Skin and Tissue Defects on Foot Heel
    LIU Guijiang,YUAN Min
    2013, 9 (6):  357-360.  DOI: 10.3969/j.issn.1673-0364.2013.06.016
    Abstract ( 408 )  
    Flaps for the repair of skin and tissue defects of foot heel were mainly divided into two kinds:known vascular flap and unknown vascular flap. The former mainly includes lateral crural flap, medial crural flap, dorsalis pedis flap and so on;The latter mainly includes medial plantar flap, lateral flap, supramalleolar retrograde island flap, neurocutaneous vascular flap (sural neurovascular flap and saphenous vascular flap) and so on. In this paper, the anatomical basis, advantages and disadvantages of flaps for the repair of skin and tissue defects of foot heel were reviewed.
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