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Journal of Tissue Engineering and Reconstructive Surgery    2021, 17 (6): 1-.   Abstract （496）      PDF（pc） （2707KB）（5342）       Knowledge map    Save Related Articles | Metrics | Comments（0）

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Evaluation of facial injection filling materials for medical aesthetics ZHAO Chenyu, LI Chongchong, SUN Xue, et al Journal of Tissue Engineering and Reconstructive Surgery    2023, 19 (5): 517-.   Abstract （411）      PDF（pc） （874KB）（3173）       Knowledge map    Save With economic development and technological progress, the demand for medical aesthetics has increased sig nificantly, and medical biomaterials are widely used. It is necessary to further improve the evaluation of their effectiveness and safety. At present, the evaluation of its physicochemical properties and biology is adopted in China. However, the clinical effec tiveness is a multi-faceted evaluation without unified criteria. Most of the evaluation mainly adopts objective indicators for quan titative analysis, while subjective feelings are secondary criteria. In this paper, the main facial fillers and the evaluation methods of their physicochemical properties were reviewed. Related Articles | Metrics | Comments（0）

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Research progress on the mechanism of skin aging caused by ultraviolet radiation CHEN Heng, WANG Jue, ZHOU Xu Journal of Tissue Engineering and Reconstructive Surgery    2024, 20 (3): 382-.   Abstract （194）      PDF（pc） （992KB）（2039）       Knowledge map    Save Skin exposed to sunlight for a long period of time will have impaired function and even genetic material alteration， which is manifested by aging characteristics such as water loss， elasticity loss， wrinkle growth， melanin deposition and dryness. There are many ways to cause skin photoaging and the mechanism is complex， the ultraviolet light in sunlight has a particularly obvious effect on skin aging， the ultraviolet light that can act on the skin is divided into two kinds： UVA and UVB. They mainly act on the skin through five mechanisms that lead to photoaging： oxidative stress， damaging genetic material， changing the epidermal microbial community， destroying the function and structure of organelles， and reshaping the extracellular matrix （ECM）.In this paper， these five mechanisms were reviewed， and research directions and prospects in this field were proposed. Related Articles | Metrics | Comments（0）

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Progress in the Treatment of Hypertrophic Scars and Keloids MA Qianyu,WU Xiaoli Journal of Tissue Engineering and Reconstructive Surgery    2020, 16 (1): 1-5.   DOI: 10.3969/j.issn.1673-0364.2020.01.001 Abstract （929）      PDF（pc） （736KB）（1839）       Knowledge map    Save Related Articles | Metrics | Comments（0）

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Overview of sensitive skin and treatment progress of aesthetic medicine LU Nan, WU Min, SONG Jiao, et al Journal of Tissue Engineering and Reconstructive Surgery    2023, 19 (3): 323-.   Abstract （291）      PDF（pc） （708KB）（1449）       Knowledge map    Save 敏感性皮肤 ；　机制 ；　诊断 ；　治疗 ；　光电治疗 Related Articles | Metrics | Comments（0）

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Analysis of mutation type and clinical significance of congenital melanocytic nevi ZHAO Yifei, ZOU Yun, CHEN Hui, et al Journal of Tissue Engineering and Reconstructive Surgery    2023, 19 (3): 258-.   Abstract （312）      PDF（pc） （843KB）（1353）       Knowledge map    Save Objective To explore the molecular characteristics of giant congenital melanocytic nevi (GCMN) and their clinical significance. Methods The samples of patients diagnosed with GCMN were subjected whole-exome sequencing and bio-information analysis to clarify the pathogenic genes and distribution patterns. Results In 50 samples (25 pairs of tissues and blood) from 25 patients, 21 patients had somatic mutations, including NRAS gene (19 cases) and BRAF gene (1 case). New mutations were detected in 2 patients’ lesions and blood, and the mutant genes were MET gene and IDH1 gene. In addition, no causative mutation was detected in 4 patients. There was no statistic difference between GCMN genotype and phenotype. Conclusion NRAS somatic mutation is the most common mutation in GCMN, and BRAF gene has also been detected. Potential new mutated IDH1 and MET genes were also found. Related Articles | Metrics | Comments（0）

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Journal of Tissue Engineering and Reconstructive Surgery    2021, 17 (6): 565-.   Abstract （475）      PDF（pc） （2380KB）（1178）       Knowledge map    Save   Related Articles | Metrics | Comments（0）

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Research progress of tissue engineering ligament and scaffold materials ZHONG Rui, GAO Jingyu, YAN Chengyuan, et al Journal of Tissue Engineering and Reconstructive Surgery    2023, 19 (3): 308-.   Abstract （224）      PDF（pc） （927KB）（1135）       Knowledge map    Save 　The reconstruction scheme of the existing artificial ligament products has been relatively mature in clinical ap plication. In order to prevent the occurrence of postoperative complications such as difficult tendon-bone healing, expansion of the bone tunnel, synovial inflammatory reaction, infection, and external fixation loosening after ligament reconstruction, tendon tissue construction using tissue engineering technology has become a possible development direction in the future. In this paper, the progress of the construction of tissue-engineered tendon and its scaffold materials was reviewed, the urgent problems to be solved and the future development direction were discussed. Related Articles | Metrics | Comments（0）

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New advances in the study of scaffold materials for cartilage tissue engineering YUE Guangren, WANG Ximei, LI Yu Journal of Tissue Engineering and Reconstructive Surgery    2023, 19 (4): 408-413.   Abstract （396）      PDF（pc） （875KB）（1098）       Knowledge map    Save Lacking blood vessels and nerve nourishment, cartilage has limited ability to repair and regenerate. Combining scaffolds, cells and active factors, tissue engineering has been considered as an important new direction for repairing cartilage injury. Scaffold plays an important role in the cartilage regeneration process, not only providing a support site for cell adhesion, but also improving the local microenvironment and affecting cell proliferation and differentiation. Many materials have been used to make biodegradable scaffolds: natural materials, synthetic materials and composite materials. In this paper, the materials that have been relatively widely used in cartilage tissue engineering were reviewed so as to provide valuable reference for researchers in this field. Related Articles | Metrics | Comments（0）

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An Improved Rat Tail Animal Model of Hypertrophic Scar XU Xiangwen,KUANG Yimin,HUANG Xin,GAO Yashan,LI Haizhou,GU Shuchen,ZAN Tao Journal of Tissue Engineering and Reconstructive Surgery    2020, 16 (1): 22-26.   DOI: 10.3969/j.issn.1673-0364.2020.01.005 Abstract （653）      PDF（pc） （5820KB）（1098）       Knowledge map    Save Related Articles | Metrics | Comments（0）

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Research progress of signal pathways in soft palate development  ZHAO Jingjing, WU Di Journal of Tissue Engineering and Reconstructive Surgery    2023, 19 (1): 75-.   Abstract （137）      PDF（pc） （1131KB）（1088）       Knowledge map    Save 　Cleft palate can adversely affect speech, swallowing, breathing and hearing. The latest progress in the study of soft palate development shows that the development of soft palate may be regulated by different pathways related to the development of hard palate. It is necessary to study the signal pathways involved in the development of soft palate. The soft palate includes three cell types: epithelial cells, cranial nerve crest-derived mesenchymal cells and muscle-derived cells, which interact with each other. In this paper, the research progress of soft palate development signal pathway in recent years was reviewed, in order to improve our understanding of the regulation mechanism of soft palate development, and provide a basis for improving the treatment of cleft soft palate in the future. Related Articles | Metrics | Comments（0）

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Application of Acellular Dermal Matrix in Tissue Engineering and Regenerative Medicine HUANG Cheng,LUO Xusong Journal of Tissue Engineering and Reconstructive Surgery    2020, 16 (1): 65-66.   DOI: 10.3969/j.issn.1673-0364.2020.01.017 Abstract （847）      PDF（pc） （659KB）（1073）       Knowledge map    Save Related Articles | Metrics | Comments（0）

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Case Report:Crouzon Syndrome WANG Jing,YAN Qing,HE Junping,QIU Dezhi,WANG Gang Journal of Tissue Engineering and Reconstructive Surgery    2020, 16 (1): 62-64.   DOI: 10.3969/j.issn.1673-0364.2020.01.016 Abstract （1030）      PDF（pc） （3230KB）（1068）       Knowledge map    Save Related Articles | Metrics | Comments（0）

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Formation and correction of facial dynamic depression YUAN Ye, LI Qiang, LI Senkai Journal of Tissue Engineering and Reconstructive Surgery    2023, 19 (2): 206-.   Abstract （180）      PDF（pc） （840KB）（1064）       Knowledge map    Save 　Facial dynamic depression occurs or aggravates during facial expression activities, mainly including dimples on the cheeks and depression deformities caused by scars between the mimetic and the dermis. In this paper, the formation mecha nism of different types of facial dynamic depression and the current methods for deformity correction were all reviewed. Related Articles | Metrics | Comments（0）

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Related Complications in Orthognathic Surgery of Cleft Lip and Palate LU Ye,YIN Ningbei,SONG Tao Journal of Tissue Engineering and Reconstructive Surgery    2020, 16 (1): 67-69.   DOI: 10.3969/j.issn.1673-0364.2020.01.018 Abstract （495）      PDF（pc） （697KB）（1028）       Knowledge map    Save Related Articles | Metrics | Comments（0）

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Progress in prevention and treatment of skin flap necrosis induced by ischemic reperfusion SUN Jiayuan, HOU Rui, ZHANG Ruhong Journal of Tissue Engineering and Reconstructive Surgery    2023, 19 (2): 193-.   Abstract （186）      PDF（pc） （905KB）（1015）       Knowledge map    Save 　Flap ischemia-reperfusion injury often occurs after skin flap transplantation surgery, which is an important cause of partial or total necrosis of skin flap. Nowadays, the pathogenesis of flap ischemia-reperfusion injury is not completely clear. It is generally believed that FIRI is related to the outbreak of reactive oxygen species, the infiltration of neutrophils and the ob struction of revascularization. Nanozyme is a kind of nano-material with enzyme-like properties, which has the advantages of low cost, good stability, simple preparation and easy storage. It can directly regulate the redox balance in cells and overcome many limitations of natural enzyme in enzyme therapy. As an ideal antioxidant, nanozyme will play a vital role in the field of biomed icine. In this paper, the mechanism of flap ischemia-reperfusion injury and the research and clinical application of treatment methods in recent years were reviewed, and the application of nanozyme in ischemia-reperfusion injury diseases was introduced, aiming to provide theoretical basis and new thinking about the treatment of flap ischemia-reperfusion injury. Related Articles | Metrics | Comments（0）

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Classification of Nasal Alar Hypertrophy and Progress in Clinical Treatment Zongqin PAN, Journal of Tissue Engineering and Reconstructive Surgery    2020, 16 (3): 257-259.   DOI: 10.3969/j.issn.1673-0364.2020.03.021 Abstract （547）   HTML （31）    PDF（pc） （692KB）（1005）       Knowledge map    Save Nasal alar hypertrophy is a group of clinical manifestations including wide nasal base, hypertrophy and expansion of the nasal alar. At present, the main treatments of nasal alar hypertrophy are embedding suture and tissue resection. In this paper, the alar hypertrophy was classified according to the different clinical manifestations of alar hypertrophy and its clinical treatment progress was reviewed. Reference | Related Articles | Metrics | Comments（0）

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Research progress of three dimensional bio-printing technology for formation of vascular network in bone tissue ZHAI Chuanxing, WANG Zhimeng, WANG Guodong, et al Journal of Tissue Engineering and Reconstructive Surgery    2023, 19 (3): 298-.   Abstract （170）      PDF（pc） （913KB）（1004）       Knowledge map    Save Vascularization of bone grafts is one of the major challenges facing bone tissue engineering (BTE). The ultimate goal of the construction of vascularized BTE is to provide a bone environment rich in functional vascular networks to achieve efficient bone integration and accelerate the functional recovery after implantation. In this paper, the research progress of 3D bio-printing in the formation of vascular network in bone tissue was reviewed, the formation mechanism of vascular network and the characteristics of 3D bio-printing technology were elaborated, the current vascularization strategies in BTE were summarized, and its development prospects were prospected. Related Articles | Metrics | Comments（0）

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The incidence and risk factors of breast cancer-related lymphedema ZHANG Yingying, LI Hua, GUAN Jiaqin, et al Journal of Tissue Engineering and Reconstructive Surgery    2023, 19 (3): 242-.   Abstract （438）      PDF（pc） （1127KB）（1001）       Knowledge map    Save Objective　To explore the incidence rate, severity and risk factors of breast cancer-related lymphedema (BCRL) among breast cancer survivors. Methods　Data collected from 128 patients underwent breast cancer operation during September 1 to December 31, 2019. All the patients were female, aging (49.0±6.8) years (29-81 years). The Norman questionnaire and arm circumference measurement were used to evaluate the BCRL status and treatment status of breast cancer patients from subjective and objective perspectives at 6, 12, 24 and 36 months after surgery separately. The influence of the correlation factors on BRCL occurrence was analyzed by Logistic analysis. Results　BRCL incidences were 9.4%, 25%, 23.4% and 23.4% at 6, 12, 24, 36 months according to arm circumference measurement, while 12.5%, 26.6%, 25.0% and 25.0% by Norman questionnaire. Among the 128 patients, 30 were diagnosed with BCRL after breast cancer surgery, among which the incidence of stage Ⅰ lymphedema, stage Ⅱ lymphedema and stage Ⅲ lymphedema were 15.6%, 6.3% and 1.6%, respectively. Age, body mass index (BMI)  radiotherapy, the number of positive lymph nodes and surgery method showed differences between the the BCRL group and control group. Both CDT or LVA showed improvement for the BCRL patients. Conclusion　BCRL is a common complication for breast cancer patients after surgery. It can be fairly diagnosed in the first year after surgery without the increasing incidence of BCRL over time throughout 3 years. BMI, radiotherapy were found to be independent risk factors in the development of BCRL in this study. Related Articles | Metrics | Comments（0）

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Journal of Tissue Engineering and Reconstructive Surgery    2021, 17 (3): 269-.   Abstract （285）      PDF（pc） （1790KB）（957）       Knowledge map    Save Related Articles | Metrics | Comments（0）