诊断学理论与实践 ›› 2016, Vol. 15 ›› Issue (05): 482-486.doi: 10.16150/j.1671-2870.2016.05.010
康慧莉, 董屹婕, 詹维伟
收稿日期:
2016-09-14
出版日期:
2016-10-25
发布日期:
2022-07-27
通讯作者:
詹维伟 E-mail: 13032131350@126.com
KANG Huili, DONG Yijie, ZHAN Weiwei
Received:
2016-09-14
Online:
2016-10-25
Published:
2022-07-27
摘要: 目的: 探讨甲状腺微小乳头状癌(papillary thyroid microcarcinoma,PTMC)的临床病理和超声影像特征,并分析其与中央组淋巴结转移间的相关性。方法: 回顾性分析826例甲状腺PTMC患者的临床资料,评估各指标(性别、年龄、肿瘤多灶性、肿瘤最大径、肿瘤双侧性、是否合并慢性淋巴细胞性甲状腺炎)和超声影像特征,并探讨其与颈部淋巴结转移间的相关性。进行单变量和多变量分析,以确定PTMC患者发生颈部淋巴结转移的相关因素。结果: 826例PTMC患者中有216例(26.15%)存在颈部淋巴结转移。单变量和多变量分析显示,患者为男性(OR=1.600,P<0.001)、年龄≤45岁(OR=2.020,P<0.001)、肿瘤最大径>5 mm(OR=2.371,P<0.001)、超声显示病灶内存在微钙化(OR=1.407,P=0.042)是发生颈部淋巴结转移的危险因素;而合并慢性淋巴细胞性甲状腺炎(OR=0.492,P=0.016)则与颈部淋巴结转移的发生呈负相关;肿瘤多灶性、肿瘤双侧性及其余超声特征与颈部淋巴结转移间并无相关性。结论: 男性、年龄≤45岁、肿瘤最大径>5 mm、超声显示病灶内存在微钙化是PTMC发生颈部淋巴结转移的危险因素,可作为颈淋巴结清扫术的参考依据,而合并慢性淋巴细胞性甲状腺炎则可视为颈部淋巴结转移的保护因素。
中图分类号:
康慧莉, 董屹婕, 詹维伟. 甲状腺微小乳头状癌淋巴结转移的相关因素研究[J]. 诊断学理论与实践, 2016, 15(05): 482-486.
KANG Huili, DONG Yijie, ZHAN Weiwei. Relevant factor analysis of cervical lymph nodes metastasis in papillary thyroid microcarcinoma[J]. Journal of Diagnostics Concepts & Practice, 2016, 15(05): 482-486.
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