Abstract: Objective To examine feasibility and safety of robotic pancreatectomy with vascular resection and reconstruction in patients with locally advanced pancreatic cancer. Methods The authors evaluated 59 patients who underwent pancreatectomy with vascular resection and reconstruction from August 2011 to September 2017 dividing into robotic pancreatic surgery group (n=20) and open pancreatic surgery group (n=39) retrospectively. Pancreatic ductal adenocarcinoma was diagnosed 53 cases pathologically and intraductal papillary mucinous cancer 6 cases. The patients were all locally advanced pancreatic cancer including 53 cases in stage Ⅱ and 6 cases in stage Ⅲ. Intraoperative data and postoperative recovery in two groups were compared. Results Mean operative time in robotic pancreatic surgery group was (328.9±17.8) min. Mean blood loss was(568.4±72.6) mL. Grade B/C pancreatic fistula was found in 4 cases, biliary leak in 1 case and postoperative hemorrhage in 4 cases of whom 3 cases were re-operated. Mean postoperative hospital stay was (28.8±5.7) d. Mean operating time in open pancreatic surgery group was(358.5±17.2) min. Mean blood loss was (801.3±113.2) mL. Grade B/C pancreatic fistula was found in 12 cases, biliary leak in 5 cases and postoperative hemorrhage in 4 cases of whom 3 cases were re-operated. Mean postoperative hospital stay was (31.3±5.1) d. The patients of two groups were all recovered after postoperative treatment and discharged without mortalily. The mean blood loss was less （P=0.032） and the postoperative hospital stay was shorter （P=0.011）in robotic pancreatic surgery group when compared those in open pancreatic surgery group, respectively. Conclusions Robotic pancreatectomy with vascular resection and reconstruction was safe and feasible.

Key words: Robotic surgery, Vascular reconstruction, Pancreatic cancer