Abstract: Objective To evaluate the effect of Jiang Ru formula combined with breast mammoplasty and continuous negative pressure irrigation for the treatment of refractory plasma cell mastitis.Methods From January 2016 to December 2018,42 patients with refractory plasma cell mastitis were retrospectively analyzed.Patients were given Jiang Ru formula one month before operation till one month after operation,one dose of Jiang Ru formula a day,all lesions were thoroughly removed in the operation,the breast was repaired with one-stage breast mammoplasty,then followed continuous negative pressure irrigation after operation.The effect,adverse reactions and satisfied degree were observed.Results The cure rate was 100%(42/42),the total effective rate was 100%(42/42),the recurrence rate was 0%(0/42).The average wound healing time was 8.29 days,the average recovery time was 42.29 days,and no allergy or adverse reactions were observed.The overall satisfaction of patient was 5(n=28,67%),4(n=12,29%)and 3(n=2,5%).Conclusion Jiang Ru formula combined with breast mammoplasty and continuous negative pressure irrigation is an effective method for the treatment of refractory plasma cell mastitis.

Key words: Refractory plasma cell mastitis, Jiang Ru formula