Loading...

Table of Content

    23 July 2020, Volume 13 Issue 5 Previous Issue    Next Issue
    For Selected: Toggle Thumbnails
    Special issue of pediatric plastic surgery
    Clinical Application of the Pulsed Dye Laser for the Treatment of Infantile Hemangiomas in Neonates
    ZHANG Wenxian,GAO Yang,YANG Yifan,XUE Lei,LI Fangfang,CAO Minna
    2017, 13 (5):  241-243.  DOI: 10.3969/j.issn.1673-0364.2017.05.001
    Abstract ( 453 )  
    Objective To explore the feasibility and safety of the pulsed dye laser (PDL) for the treatment of infantile hemangiomas in neonates. Methods From January 2015 to November 2016, neonates with infantile hemangiomas treated by PDL were retrospectively analyzed. All patients were diagnosed as infantile hemangiomas and accepted at least one time of therapy. Photo and ultrasound were taken before and after treatment. The neonates were graded according to the degree of regression of hemangioma. Results A total of 112 neonates (33 males, 79 females) with infantile hemangiomas accepted 217 times of PDL therapy. The therapeutic effects of these neonates were evaluated, including 5 cases with poor effects, 13 cases in general, 27 cases with good results and 67 excellent cases. 95.54% patients got acceptable results, 83.93% patients achieved good or better results. After treatment, blisters were observed in 6 patients and partial rupture was observed in one patient. Twelve patients left hyperpigmentation after the hemangiomas were cured. Conclusion PDL is a safe and effective method for the treatment of infantile hemangiomas in neonates.
    Related Articles | Metrics
    Feasibility Analysis of Sirolimus Treatment for KMS in Young Children
    SHAN Yuhua,CHU Jun,HU Ming,XU Min,CHEN Qimin
    2017, 13 (5):  244-247.  DOI: 10.3969/j.issn.1673-0364.2017.05.002
    Abstract ( 524 )  
    Objective To explore the feasibility of sirolimus treatment for Kasabach Merritt Syndrome (KMS) in young children. Methods From the beginning of 2013 to the end of 2016, 15 patients diagnosed as KMS were retrospectively analyzed. All the patients received prednisolone therapy combined with supportive treatment like platelet infusion. Thirteen patients lacking positive response were treated with sirolimus. Results Among those 13 cases, 1 patient unfortunately terminated the treatment because of severe infection, other 12 patients experienced rapid recovery of hemogram. Tumor volume also decreased dramatically in 11 cases, the other one had unsatisfactory responding with an almost controlled hemogram, but unchanged tumor volume. Nine cases had withdrawn the medication, no recurrence reported in the following observation. Compared with the patients received both sirolimus and propranolol, patients received sirolimus alone manifested no significant differences in hemogram recovery, DIC remission and tumor involution ( P>0.05). Serous fibrinogen (FIB) responding to the medication during early stage of the pathology can predict the prognosis of tumor volume clearance afterwards (Pearson correlation coefficient=-0.629, P<0.05). Conclusion Sirolimus together with prednisolone should be valued as the first line treatment of KMS. The drug has effective restoring of coagulopathy so as its reversing impact on the haemangioma proliferation. More importantly, the effect is constant, so that a withdrawal after stabilization turns out to be secure and feasible.
    Related Articles | Metrics
    Application of Semiconductor Laser Combined with Polidocanol under the Digital Subtraction Angiography for the Treatment of Venous Malformations in Children
    ZHANG Wenxian,GAO Yang,XUE Lei,YANG Yifan,DU Ya,LIU Qi,ZHANG Yunzhen
    2017, 13 (5):  248-251.  DOI: 10.3969/j.issn.1673-0364.2017.05.003
    Abstract ( 419 )  
    Objective To evaluate the effectiveness and safety of combined application of semiconductor laser and polidocanol under the digital subtraction angiography (DSA) for the treatment of venous malformations in children. Methods From August 2016 to May 2017, totally 57 patients of VMs were treated by semiconductor laser combined with polidocanol. All patients diagnosed as VM according to MRI examination and evaluation by 2 experienced physicians. All patients accepted at least once combined therapy and all the treatment were finished under the DSA. Three months after the therapy, all patients got MRI re-examination. The effectiveness is evaluated by the improvement of the lesions. Results Totally 89 times combined therapy were performed, average 1.56 ±0.12 times per child. Twelve patients were cured and 42 children got improvement of the lesion or their clinical symptoms. Three patients did not achieve any improvement. The cure rate was 21.04% and the total efficiency rate was 94.74%. The main side effects were swelling, pain and bubble. Twenty-four children appeared a local swelling of the lesion region after treatment, and improved spontaneously. Seventeen patients felt painful after the treatment and regressed in 24 hours after the treatment finished. Three children appeared a bubble at the therapy location, 2 patients regressed after 2 weeks without any special treatment, but one child appeared a secondary ulcer after the bubble was ruptured. Although the ulceration was healed after 2 weeks ' wound nursing, but the scar was left inevitably. Conclusion The combined application of semiconductor laser and polidocanol under the DSA for the treatment of venous malformations in children is safe and effective. Especially in those children who have draining veins in their lesions, the therapy is helpful in improving the therapy efficiency and reduce the treatment times.
    Related Articles | Metrics
    The Mid-term Efficacy of Ablative Lasers in Treating Children's Congenital Melanocytic Nevi of Eyelids and Periorbital Areas
    GU Yifei,CHEN Hui,MA Gang,HU Li,WANG Yongying,ZHU Jiafang,LIN Xiaoxi
    2017, 13 (5):  252-255.  DOI: 10.3969/j.issn.1673-0364.2017.05.004
    Abstract ( 490 )  
    Objective To explore the efficacy of ablative lasers in treating children's congenital melanocytic nevi of eyelids and periorbital areas. Methods From January 2014 to December 2016, 22 children received ablative laser therapies, including carbon dioxide laser or Er:bium laser. The interval duration was at least 1 month and the follow-up time was at least 6 months. Results were graded as percent clearance in five grades according to the pre-operative and post-operative photographs. Results All 22 patients received mean 7.4 laser treatment sessions with a mean follow-up of 23 months. Among the 22 patients, the poor, fair, good, excellent and clearance ones were 9, 4, 5, 2 and 2, respectively, and the effective rate was 41%. Dyspigmentation was observed in 3 cases. Conclusion Using ablative lasers to treat congenital melanocytic nevi of eyelids and periorbital areas is safe and effective.
    Related Articles | Metrics
    Application of Skin Replantation and Vacuum Assisted Closure Technology for Degloving Injuries in 42 Children
    ZHU Zhenhong,YIN Wei,HU Guanhong,HUANG Zhijian,MA Zhourui
    2017, 13 (5):  256-258.  DOI: 10.3969/j.issn.1673-0364.2017.05.005
    Abstract ( 446 )  
    Objective To investigate the clinical efficacy of skin replantation combined with vacuum assisted closure (VAC) technology for the treatment of degloving injuries in children. Methods From August 2013 to August 2017, 42 patients (42 wounds) with large area of degloving injury (32 in limbs and legs, 8 in trunk and 2 in head )were included in this study. Skin replantation and VAC technique were applied in all patients after debridement. The skin condition was observed. Results The flaps all survived in 29 cases (69.05%). In 7 cases, the survival area of the flap was more than 75% (14.29%) because of local skin necrosis which healed after a short term dressing. In 6 cases, the survival area of the flap was more than 50% and less than 75% (14.29%), and the residue wound were healed by secondary skin grafting. Conclusion The skin replantation combined with VAC technology is an effective method for the treatment of degloving injuries in children. It can not only improve the skin graft survival significantly, but also reduce the incidence of secondary operation.
    Related Articles | Metrics
    A Retrospective Study on Keloid Formation after Syndactyly Release
    ZHU Wei,TIAN Xiaofei,CHEN Wei
    2017, 13 (5):  259-262.  DOI: 10.3969/j.issn.1673-0364.2017.05.006
    Abstract ( 484 )  
    Objective To explore the causes of keloid after syndactyly release by analyzing the correlation of preoperative toe forms, the degree of joining, surgical procedure, postoperative incision healing with postoperative keloid. Methods From January 2011 to January 2016, 253 children with syndactyly release were retrospectively reviewed to investigate the preoperative toe forms, the degree of joining, surgical procedure, postoperative incision healing and postoperative keloid. SPSS 22.0 software was used for the statistical analysis of the relationship of preoperative toe forms, the degree of joining, surgical procedure, post-operative incision healing with postoperative keloid. Results Eight children occurred keloid after syndactyly release. These pa-tients all had pachydactyly, complete syndactyly, and all of them received skin-grafting. After operation, the difference between groups was statistically significant in pachydactyly, the degree of joining and skin-grafting (P0.05). Conclusion There is highly correlation between pachydactyly and keloid formation after syndactyly release, pachydactyly may be the main cause of keloid formation after syndactyly release. Meanwhile, there are relevance on complete syndactyly and skin-grafting.
    Related Articles | Metrics
    Composite Treatments of Scar in Children
    LIANG Yimin
    2017, 13 (5):  263-278.  DOI: 10.3969/j.issn.1673-0364.2017.05.007
    Abstract ( 498 )  
    Symptomatic scars can cause appearance disfigurements and functional damages. Beyond that, scars may be associated with a lot of physical comorbidities including hypertrichosis, dyshidrosis, pain, pruritus, dysesthesias, and functional impairments. Although a plethora of scar treatment exists, specific management guidelines for the pediatric populations do not. New modalities such as composite scar treatment, autologous fat transfer, and ablative fractional laser suggest a promising future for children who developed symptomatic scars. In this paper, state-of-the-art scar treatment strategies relate to the pediatric populations were reviewed.
    Related Articles | Metrics
    Syndrome Associated with Vascular Anomalies:Diagnosis and Treatment
    XU Yuan,YUAN Siming
    2017, 13 (5):  268-272.  DOI: 10.3969/j.issn.1673-0364.2017.05.008
    Abstract ( 807 )  
    Vascular anomalies is a general term for all the diseases of blood vessel and lymph vessel abnormalities. The clinical symptom and classification of vascular anomalies are complex and controversial. Many types of vascular anomalies show the typical clinical symptoms when combined by other diseases, which is summed up as syndrome associated with vasculars nomalies. In this paper, the diagnosis and treatment of several typical syndrome associated with vascular anomalies were summarized.
    Related Articles | Metrics
    Therapeutic Progress in Microform Cleft Lip
    SHI Bing
    2017, 13 (5):  273-275.  DOI: 10.3969/j.issn.1673-0364.2017.05.009
    Abstract ( 446 )  
    Microform cleft lip is the mildest type of cleft lip. Its pathological characteristics are aneretic orbicularis oris muscle and disrupted nasolabial muscle tension line. So the paramount significance of microform cleft lip repair is to rebuild the continuity of orbicularis oris muscle and to reconstruct the nasolabial muscle tension line. Conventional repair of microform cleft lip leads to obvious labial scars, so repair operation has gradually transformed to intraoral approaches. Nowadays, the individualized repair is popular, which should complete the functional correction without obvious labial scars.
    Related Articles | Metrics
    Advances and Retrospect in One-stage Repair of Bilateral Cleft Lip
    CHENG Qi,ZHOU Qixing,HAN Kun,YANG Wen,ZHANG Yong
    2017, 13 (5):  276-278.  DOI: 10.3969/j.issn.1673-0364.2017.05.010
    Abstract ( 402 )  
    Congenital bilateral cleft lip is one of the severe oral and maxillofacial deformities. Due to its unique characteristics and anatomical abnormalities, the result of first-stage repair directly related to the long-term facial development, appearance and physiological function and second-stage repair. So primary repair of the bilateral cleft lip should reduce the incidence of postoperative nasolabial deformities and the degree of deformity as far as possible. In this paper, according to the recent literatures, the determined advances on first-stage repair of bilateral cleft lip were reviewed.
    Related Articles | Metrics
    Progress in the Operative Therapy of Congenital Blepharoptosis
    LIU Bing
    2017, 13 (5):  279-282.  DOI: 10.3969/j.issn.1673-0364.2017.05.011
    Abstract ( 419 )  
    Congenital blepharoptosis, caused by levator muscle dysgenesis or the defect of the central and peripheral nerves that govern the levator muscle, is a common disease in clinical practice. The blepharoptosis not only affects the appearance, but can lead to deprivation amblyopia in severe cases which disturbs the visual function. Timely correction is, therefore, critical. The purpose of ptosis correction is to renew normal palpebral fissure height, to get rid of the interference of visual axis caused by ptosis, to pursue the good functional and cosmetic outcome at the same time. In this paper, the operation opportunity and the surgical treatments of congenital blepharoptosis were reviewed.
    Related Articles | Metrics
    Original article
    Effects of Recombinant Periostin on Proliferation and Osteogenic Differentiation of Cranial Suture Cells in TWIST1+/- Mouse
    BAI Shanshan,LI Junxian,LI Dong,XU Liang,DUAN Huichuan,YU Zheyuan,YUAN Jie,WEI Min
    2017, 13 (5):  283-286.  DOI: 10.3969/j.issn.1673-0364.2017.05.012
    Abstract ( 372 )  
    Objective To observe the effects of recombinant Periostin on proliferation and osteogenic differentiation of cranial suture cells of coronal suture in TWIST1+/-mouse. Methods Cranial suture cells were separated and extracted from coronal suture of TWIST1+/-mouse. The cells were divided into 4 groups according to different concentration of recombinant Periostin: 0 μg/L, 50 μg/L, 100 μg/L, 200 μg/L group. CCK-8 method was used to detect the cell proliferation of cranial suture cells; Alkaline Phosphatase kit was used to detect the ALP activity; Real-Time PCR and Western Blot were used to detect the expression of osteogenic differentiation markers: OCN, OPN, BSP and COL-1. Results CCK-8 test showed that, compared with 0 μg/L group, other Periostin groups inhibited cranial suture cell proliferation in some degree (P<0.05). ALP activity test showed that, after osteoinduction for 10 days, compared with 0 μg/L group, ALP activity of 50 μg/L, 100 μg/L, 200 μg/L Periostin groups were significantly decreased (P<0.05). Real-Time PCR and Western Blot showed that, compared with 0 μg/L group, other groups significantly decreased the expression of OCN, OPN, BSP and COL-1 (P<0.05). Conclusion Different concentrations (50 μg/L, 100μg/L, 200μg/L) of recombinant Periostin can inhibit the proliferation and osteogenic differentiation of cranial suture cells of coronal suture in TWIST1+/-Mouse.
    Related Articles | Metrics
    A Preliminary Study of SDF-1 in Stem Cell Homing-guided Tissue Regeneration
    HUANG Xiao,CHEN Hui,LIU Yujian,WANG Jun
    2017, 13 (5):  287-298.  DOI: 10.3969/j.issn.1673-0364.2017.05.013
    Abstract ( 524 )  
    Objective To investigate the chemotaxis of stromal cell derived factor-1 (SDF1) in vitro and in vivo. Methods Bone marrow mesenchymal stem cells (BMSCs) were cultivated from SD rats. Transwell test was used to evaluate the influences of different concentration of SDF1 on chemotaxis of BMSC. MTT test was used to analyze the effects of different concentration of SDF1 on the cell viability of BMSC. 100 ng/mL SDF1-loaded PLGA was implanted in nude mice to study the the chemotaxis of SDF1 in vivo. Results All 4 groups of SDF1 (10 ng/mL, 50 ng/mL, 100 ng/mL and 200 ng/mL) recruited more BMSC than the control group, and 100 ng/mL SDF1 showed better results than the other groups. 200 ng/mL SDF1 deceased cell viability of BMSC on day 1, 4 and 7, while 10 ng/mL, 50 ng/mL and 100 ng/mL SDF1 had no effects on the the viability of BMSC. In vivo analysis showed that 100 ng/mL SDF1 could promote cell recruitment. Conclusion 100 ng/mL SDF1 could effectively promote BMSC recruitment without influence on cell viability in vitro and 100 ng/mL SDF1 could promote cell homing in vivo.
    Related Articles | Metrics
    Clinical Treatment of Hump Nose Associated with Nasal Deviation Deformity
    ZHOU Xu,OU Yangxue,LI Chongzhao,CHEN Lin,LI Kongying
    2017, 13 (5):  291-293.  DOI: 10.3969/j.issn.1673-0364.2017.05.014
    Abstract ( 376 )  
    Objective To explore the comprehensive surgical technique for hump nose combined with nasal deviation deformity, and the objective evaluation method of operative effect. Methods The nasal contour was reconstructed and the nasal ventilation function was improved through the multi plane nasal osteotomy and the transplantation of the nasal septal cartilage. The changes of nasal ventilation were measured by nasal resistance measurement (RM) and nasal acoustic reflex (AR) before and after operation. Results Followed up for 4-8 months after operation, 16 cases were all satisfied with the nasal appearance. Only 1 case felt no obvious change of nasal ventilation function, the rest of the patients felt obvious change, comparing with preoperative nasal ventilation consciousness. No recurrence and complications were observed. According to the results of RM and AR, the nasal minimal cross-sectional area , the nasal volume and nasal resistance all had significant improvement postoperatively (P<0.01). Conclusion The treatment of hump nose associated with deviated nose includes the repair of nasal contour and the reconstruction of nasal ventilation function. The measurement of nasal resistance (RM) and nasal acoustic reflex (AR) can objectively evaluate the changes of nasal ventilation function.
    Related Articles | Metrics
    Clinical Observation of Steroid-Dependent Dermatitis Treated by Diode Laser
    ZHANG Xiaohong,SHEN Gan
    2017, 13 (5):  294-295.  DOI: 10.3969/j.issn.1673-0364.2017.05.015
    Abstract ( 499 )  
    Objective To observe the clinical efficacy of diode laser in treating facial steroid-dependent dermatitis. Methods From November 2012 to December 2016, 105 patients suffered steroid-dependent dermatitis were treated with 980 nm diode laser mediated by optical fiber subcutaneously. Results All patients were followed up for 6 to 36 months, the face skin was smooth and clean, and no recurrence was observed. The skin condition before and after laser treatment showed statistical difference (P<0.05). Conclusion The diode laser mediated by optical fiber is a simple and effective method for the treatment of facial steroid-dependent dermatitis with no recurrence.
    Related Articles | Metrics
    Effectiveness Comparison of Unicondylar Knee Arthroplasty and Total Knee Arthroplasty in the Treatment of Knee Osteoarthritis
    YAN Jianfeng,LI Qiang,YANG Zonghua,LI Meng
    2017, 13 (5):  296-298.  DOI: 10.3969/j.issn.1673-0364.2017.05.016
    Abstract ( 343 )  
    Objective To compare the short-term clinical effects of unicondylar knee arthroplasty (UKA) and total knee arthroplasty (TKA) in the treatment of knee osteoarthritis. Methods From January 2013 to January 2016, 61 patients with medial unicondylar knee osteoarthritis were divided into unicondylar replacement group ( n=26) and total knee arthroplasty group (n=35). The short-term clinical results of the two groups were compared. Results The difference of postoperative HSS score in both groups was not significant (P>0.05). However, the range of motion in the UKA group was significantly bigger than TKA group (P<0.05); The rate of pain relieve, blood loss, hemoglobin decrease on 3 day after operation and hospitalization stay in the UKA group were all significantly better than TKA group ( P<0.05) . Conclusion The short-term results of unicondylar knee arthroplasty and total knee arthroplasty for the treatment of knee osteoarthritis are similar. However, the unicondylar knee arthroplasty is more beneficial to postoperative recovery with less intraoperative bleeding and shorter hospital stay.
    Related Articles | Metrics
    Data analysis
    Feature Analysis of the Highly Cited Papers Published in Journal of Tissue Engineering and Reconstructive Surgery
    PAN Xian,ZHONG Bin,Gan Jiliang
    2017, 13 (5):  299-302.  DOI: 10.3969/j.issn.1673-0364.2017.05.017
    Abstract ( 320 )  
    According to the China Academic Journal Network Publishing Database in China National Knowledge Infrastructure (CNKI), the top 10 cited papers published in Journal of Tissue Engineering and Reconstructive Surgery from 2007 to 2015 were analyzed to explore the influencing factors of sci-tech periodical paper in citation frequency, and to provide reference for the editorial departments of journals in their topic selection, manuscripts review and solicitation, in order to improve the quality and the influence of the journal.
    Related Articles | Metrics