诊断学理论与实践 ›› 2018, Vol. 17 ›› Issue (03): 347-351.doi: 10.16150/j.1671-2870.2018.03.024
刘玮1, 吴歆2, 徐沪济2
收稿日期:
2018-05-15
出版日期:
2018-06-25
发布日期:
2018-06-25
通讯作者:
徐沪济 E-mail: xuhuji@smmu.edu.cn
Received:
2018-05-15
Online:
2018-06-25
Published:
2018-06-25
中图分类号:
刘玮, 吴歆, 徐沪济. 类风湿关节炎易感基因遗传背景的研究进展[J]. 诊断学理论与实践, 2018, 17(03): 347-351.
[1] Scott DL, Wolfe F, Huizinga TW.Rheumatoid arthritis[J]. Lancet,2010,376(9746):1094-1108. [2] Dai SM, Han XH, Zhao DB, et al. Prevalence of rheumatic symptoms, rheumatoid arthritis, ankylosing spondylitis,gout in Shanghai, China: a COPCORD study[J]. J Rheumatol.2003 Oct;30(10):2245-2251. [3] Kim K, Bang SY, Lee HS, et al.Update on the genetic architecture of rheumatoid arthritis[J]. Nat Rev Rheumatol,2017,13(1):13-24. [4] Stahl EA, Raychaudhuri S, Remmers EF, et al.Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci[J]. Nat Genet,2010,42(6):508-514. [5] Okada Y, Terao C, Ikari K, et al.Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population[J]. Nat Genet,2012,44(5):511-516. [6] Jiang L, Yin J, Ye L, et al.Novel risk loci for rheumatoid arthritis in Han Chinese and congruence with risk varia-nts in Europeans[J]. Arthritis Rheumatol,2014,66(5):1121-1132. [7] Okada Y, Wu D, Trynka G, et al.Genetics of rheumatoid arthritis contributes to biology and drug discovery[J]. Nature,2014,506(7488):376-381. [8] Raychaudhuri S.Recent advances in the genetics of rheumatoid arthritis[J]. Curr Opin Rheumatol,2010,22(2):109-118. [9] McInnes IB, Schett G. The pathogenesis of rheumatoid arthritis[J]. N Engl J Med,2011,365(23):2205-2219. [10] Fernando MM, Stevens CR, Walsh EC, et al.Defining the role of the MHC in autoimmunity: a review and pooled analysis[J]. PLoS Genet,2008,4(4):e1000024. [11] van der Woude D, Houwing-Duistermaat JJ, Toes RE, et al. Quantitative heritability of anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis[J]. Arthritis Rheum,2009, 60(4):916-923. [12] James EA, Moustakas AK, Bui J, et al.HLA-DR1001 presents "altered-self" peptides derived from joint-associated proteins by accepting citrulline in three of its binding pockets[J]. Arthritis Rheum,2010,62(10):2909-2918. [13] Mahdi H, Fisher BA, Källberg H, et al.Specific interaction between genotype, smoking and autoimmunity to citrullinated alpha-enolase in the etiology of rheumatoid arthritis[J]. Nat Genet,2009,41(12):1319-1324. [14] van der Woude D, Alemayehu WG, Verduijn W, et al. Gene-environment interaction influences the reactivity of autoantibodies to citrullinated antigens in rheumatoid arthritis[J]. Nat Genet,2010,42(10):814-816. [15] Bang SY, Lee KH, Cho SK, et al.Smoking increases rheumatoid arthritis susceptibility in individuals carrying the HLA-DRB1 shared epitope, regardless of rheumatoid factor or anti-cyclic citrullinated peptide antibody status[J]. Arthritis Rheum,2010,62(2):369-377. [16] Salliot C, Bombardier C, Saraux A, et al. Hormonal replacement therapy may reduce the risk for RA in women with early arthritis who carry HLA-DRB1 *01 and/or *04 alleles by protecting against the production of anti-CCP: results from the ESPOIR cohort[J]. Ann Rheum Dis.2010 Sep;69(9):1683-1686. [17] Lee HS, Lee AT, Criswell LA, et al.Several regions in the major histocompatibility complex confer risk for anti-CCP-antibody positive rheumatoid arthritis, independent of the DRB1 locus[J]. Mol Med,2008,14(5-6):293-300. [18] Ding B, Padyukov L, Lundström E, et al.Different patterns of associations with anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-ne-gative rheumatoid arthritis in the extended major histocompatibility complex region[J]. Arthritis Rheum,2009, 60(1):30-38. [19] Hu HJ, Jin EH, Yim SH, et al.Common variants at the promoter region of the APOM confer a risk of rheumatoid arthritis[J]. Exp Mol Med,2011,43(11):613-621. [20] Raychaudhuri S, Sandor C, Stahl EA, et al.Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis[J]. Nat Genet,2012,44(3):291-296. [21] Steer S, Lad B, Grumley JA, et al.Association of R602W in a protein tyrosine phosphatase gene with a high risk of rheumatoid arthritis in a British population: evidence for an early onset/disease severity effect[J]. Arthritis Rheum,2005,52(1):358-360. [22] Stanford SM, Bottini N.PTPN22: the archetypal non-HLA autoimmunity gene[J]. Nat Rev Rheumatol,2014, 10(10):602-611. [23] Kosmaczewska A, Ciszak L, Swierkot J, et al.Exogenous IL-2 controls the balance in Th1, Th17, and Treg cell distribution in patients with progressive rheumatoid arthritis treated with TNF-alpha inhibitors[J]. Inflammation,2015,38(2):765-774. [24] Barton A, Eyre S, Ke X, et al.Identification of AF4/FMR2 family, member 3 (AFF3) as a novel rheumatoid arthritis susceptibility locus and confirmation of two further pan-autoimmune susceptibility genes[J]. Hum Mol Genet,2009,18(13):2518-2522. [25] Kurreeman FA, Daha NA, Chang M, et al.Association of IL2RA and IL2RB with rheumatoid arthritis: a replication study in a Dutch population[J]. Ann Rheum Dis,2009, 68(11):1789-1790. [26] Raychaudhuri S, Remmers EF, Lee AT, et al.Common variants at CD40 and other loci confer risk of rheumatoid arthritis[J]. Nat Genet,2008,40(10):1216-1223. [27] Coornaert B, Carpentier I, Beyaert R.A20: central gatekeeper in inflammation and immunity[J]. J Biol Chem,2009,284(13):8217-8221. [28] Elsby LM, Orozco G, Denton J, et al.Functional evaluation of TNFAIP3 (A20) in rheumatoid arthritis[J]. Clin Exp Rheumatol,2010,28(5):708-714. [29] Kochi Y, Thabet MM, Suzuki A, et al.PADI4 polymorphism predisposes male smokers to rheumatoid arthritis[J]. Ann Rheum Dis,2011,70(3):512-515. [30] Qian L, Shi HX, Li XP, et al.The significance of serum peptidylarginine deiminase 4 in rheumatoid arthritis[J]. Zhonghua Nei Ke Za Zhi,2011,50(2):107-110. [31] Lee YH, Woo JH, Choi SJ, et al.Fc receptor-like 3 -169 C/T polymorphism and RA susceptibility: a meta-analysis[J]. Rheumatol Int,2010,30(7):947-953. [32] Kochi Y, Okada Y, Suzuki A, et al.A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility[J]. Nat Genet,2010,42(6):515-519. [33] Han TU, Bang SY, Kang C, et al.TRAF1 polymorphisms associated with rheumatoid arthritis susceptibility in Asians and in Caucasians[J]. Arthritis Rheum,2009,60(9):2577-2584. [34] Chen R, Wei Y, Cai Q, et al.The PADI4 gene does not contribute to genetic susceptibility to rheumatoid arthritis in Chinese Han population[J]. Rheumatol Int,2011,31(12):1631-1634. [35] Okada Y, Diogo D, Greenberg JD, et al.Integration of sequence data from a Consanguineous family with genetic data from an outbred population identifies PLB1 as a candidate rheumatoid arthritis risk gene[J]. PLoS One,2014,9(2):e87645. [36] Tarnowski M, Paradowska-Gorycka A, Dabrowska-Zamojcin E, et al.The effect of gene polymorphisms on patient responses to rheumatoid arthritis therapy[J]. Expert Opin Drug Metab Toxicol,2016,12(1):41-55. [37] Chung IM, Ketharnathan S, Thiruvengadam M, et al. Rheumatoid Arthritis: The Stride from Research to Clinical Practice[J]. Int J Mol Sci,2016,17(6),pii:E900. |
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