诊断学理论与实践 ›› 2025, Vol. 24 ›› Issue (01): 7-13.doi: 10.16150/j.1671-2870.2025.01.002
收稿日期:
2024-11-22
接受日期:
2025-02-08
出版日期:
2025-02-25
发布日期:
2025-02-25
通讯作者:
张翼飞 E-mail: zyf11192@rjh.com.cn基金资助:
ZHANG Yifei(), SHI Juan, XU Yuening
Received:
2024-11-22
Accepted:
2025-02-08
Published:
2025-02-25
Online:
2025-02-25
摘要:
2021年,全球25岁及以上的成年人中有21.1亿人超重或肥胖,其中中国人数最多,达到4.02亿。预计到2050年,全球25岁以上超重或肥胖人口将攀升至38亿,其中中国的相关人口预计将达到6.27亿。肥胖与心血管疾病、癌症、2型糖尿病等疾病的发生、发展密切相关。因此,肥胖的诊断与管理已成为全球性的重大健康挑战。但传统以体质量指数(body mass index, BMI)为核心的诊断体系存在局限性,难以精准反映脂肪分布与代谢功能异常。内脏脂肪过度蓄积是肥胖相关代谢紊乱的关键性因素,而内脏脂肪面积(visceral fat area, VFA)作为肥胖评估的客观可量化指标,与肥胖及其合并症密切相关。近年来的多项研究显示,VFA在诊断和预测肥胖及其合并症中的价值高于BMI。此外,VFA在不同干预手段对肥胖的治疗疗效评价中体现出更优的价值。中国国家标准化代谢性疾病管理中心(Metabolic Management Center, MMC)的经验表明,借助统一的生物电阻抗分析技术所测定的VFA,在肥胖诊断和临床管理中具有重要价值。未来,肥胖及其合并症的诊断和临床管理应结合多种评价手段,应通过多维度分层分析及个体化精准评估,以进一步提高肥胖的临床综合管理能力。
中图分类号:
张翼飞, 石娟, 许悦宁. 内脏脂肪在肥胖诊断及其合并症预测中的应用现状及展望[J]. 诊断学理论与实践, 2025, 24(01): 7-13.
ZHANG Yifei, SHI Juan, XU Yuening. Current applications and prospects of visceral fat in obesity diagnosis and comorbidity prediction[J]. Journal of Diagnostics Concepts & Practice, 2025, 24(01): 7-13.
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