内科理论与实践 ›› 2025, Vol. 20 ›› Issue (01): 59-62.doi: 10.16138/j.1673-6087.2025.01.12

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浅析从脾论治合并胰岛素抵抗的高血压

李华1, 杨华2()   

  1. 1.上海交通大学医学院附属瑞金医院高血压科,上海 200025
    2.上海中医药大学附属龙华医院内分泌科,上海 200032
  • 收稿日期:2024-11-11 出版日期:2025-02-28 发布日期:2025-04-30
  • 通讯作者: 杨华 E-mail:yanghua@longhua.net

Treatment of hypertensive patients with insulin resistance from the spleen

LI Hua1, YANG Hua2()   

  1. 1. Department of Hypertension, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
    2. Department of Endocrinology and Metabolism, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200030, China
  • Received:2024-11-11 Online:2025-02-28 Published:2025-04-30
  • Contact: YANG Hua E-mail:yanghua@longhua.net

摘要:

胰岛素抵抗为高血压等多种代谢相关性疾病的共同病理基础,是代谢综合征的核心病理机制。中医认为脾虚为胰岛素抵抗的核心病机。合并胰岛素抵抗的高血压患者中医证型以痰湿壅盛型为主,从脾论治可通过“同病类治”策略干预代谢综合征各组分,实现综合达标。肠道菌群失调与线粒体功能障碍的相关研究进展为从脾论治此类患者提供了理论依据。

关键词: 从脾论治, 高血压, 胰岛素抵抗, 肠道菌群, 线粒体功能

Abstract:

Insulin resistance is the common pathological basis for various metabolic-related diseases, including hypertension, and is a root cause of the metabolic syndrome. In traditional Chinese medicine, the core pathogenesis of insulin resistance is considered as spleen deficiency. The hypertensive patients with insulin resistance are more likely to be the type of stagnation of phlegm dampness. Through treating hypertensive patients with insulin resistance from the spleen, the various components of metabolic syndrome can be managed in the same disease category. The research on correlation between intestinal flora imbalance and mitochondrial dysfunction provides a theoretical basis for the treatment of the patients from spleen.

Key words: Treatment from spleen, Hypertension, Insulin resistance, Intestinal flora, Mitochondrial function

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