外科理论与实践 ›› 2024, Vol. 29 ›› Issue (06): 463-471.doi: 10.16139/j.1007-9610.2024.06.01

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髂静脉血栓性疾病治疗

谢新胜1,2, 黄玉龙1,2, 王利新1,2()   

  1. 1.复旦大学附属中山医院,上海 200032
    2.复旦大学附属中山医院(厦门),福建 厦门 361015

Treatment of iliac vein thrombotic diseases

XIE Xinsheng1,2, HUANG Yulong1,2, WANG Lixin1,2()   

  1. 1. Zhongshan Hospital, Fudan University, Shanghai 200032, China
    2. Zhongshan Hospital (Xiamen), Fudan University, Fujian Xiamen 361015, China
  • Received:2024-10-26 Online:2024-11-25 Published:2025-03-17

摘要:

目前,髂静脉血栓性疾病的治疗策略已从早期的单纯抗凝治疗、手术取栓和改善静脉回流等方法,逐步演变为包括药物溶栓、导管接触性溶栓及机械血栓清除在内的多种治疗手段。这些治疗手段趋向于微创,治疗效果和安全性均有所提升。随着治疗手段的多样化,静脉血栓栓塞症治疗理念亦不断更新,对治疗效果和安全性提出了更高标准。本文探讨了髂静脉血栓性疾病的治疗进展,旨在梳理各种临床治疗方式在髂静脉血栓性疾病治疗中的地位和作用,并为临床医师提供循证治疗建议。期待对诊断与治疗方案进一步规范化,并加强对预防的重视,以保障广大民众的血管健康。

关键词: 髂静脉血栓, 下肢深静脉血栓, 抗凝, 溶栓, 介入治疗

Abstract:

Currently, the treatment strategy for iliac venous thromboembolic disease has evolved from early approaches such as simple anticoagulation therapy, surgical thrombectomy, and venous return improvement to encompass multiple minimally invasive modalities including pharmacologic thrombolysis, catheter-directed thrombolysis (CDT), and mechanical thrombectomy. These advancements have demonstrated enhanced therapeutic efficacy and safety profiles. With the diversification of treatment modalities, the therapeutic concepts for venous thromboembolism (VTE) continue to be updated, establishing higher standards for treatment outcomes and safety. This article explored recent progress in the management of iliac venous thromboembolic disease, aiming to clarify the roles and efficacy of various treatment approaches in clinical practice while providing evidence-based treatment recommendation for clinicians. We anticipated further standardization of diagnostic and therapeutic protocols, along with increased emphasis on preventive measures, to safeguard vascular health in the general population.

Key words: Iliac vein thrombosis, Lower extremities deep venous thrombosis(LEDVT), Anticoagulation, Thrombolysis, Interventional therapy

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