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    Journal of Diagnostics Concepts & Practice    2021, 20 (04): 317-337.   DOI: 10.16150/j.1671-2870.2021.04.001
    Abstract10887)   HTML581)    PDF(pc) (3337KB)(9937)       Save
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    Global Structural Strength Analysis Methodology of a Typical TLP
    Yang LI, Zhong-min SHI, Bin XIE, Wen-hui XIE
    Ocean Engineering Equipment and Technology    2014, 1 (1): 3-13.  
    Abstract308)   HTML2)    PDF(pc) (3686KB)(6108)       Save

    We focus on the global structure strength analysis of a typical tension leg platform (TLP). The objective of the TLP global structural analysis is to check the hull global structural integrity under design environmental conditions. Firstly, a global finite element model of the entire TLP is established, the hull structure is modeled in detail, whilst the deck structure is represented through a simplified deck beam model. A hydrodynamic analysis for operation and extreme conditions is conducted to get the design wave parameters for critical wave loads. After that, wave loads are mapped to the global structure finite element model, and the tendons are modeled as spring element which represents 6 degrees of freedom and rotations. Finally, the maximum stress and its distribution trends, together with the control elements, are obtained by finite element analysis according to critical wave heading, wave periods, wave heights and wave positions. Results and the TLP analysis method proposed can be used as reference for strength analysis of other offshore platforms.

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    Journal of Diagnostics Concepts & Practice    2021, 20 (04): 401-406.   DOI: 10.16150/j.1671-2870.2021.04.014
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    Detection rate of gastric polyps and its clinical characteristics in 36 857 subjects in Shanghai
    ZHOU Yufen, WONG Bokai, LUO Fangxiu, XU Ying, DING Yanfei, YUAN Xiaoqin, CHEN Ping, WU Yunlin
    Journal of Diagnostics Concepts & Practice    2020, 19 (04): 420-425.   DOI: 10.16150/j.1671-2870.2020.04.018
    Abstract319)   HTML0)    PDF(pc) (632KB)(3587)       Save

    Objective: To explore the detection rate of gastric polyp (GP) in Shanghai and analyze its clinical characteristics. Methods: A total of 36 857 subjects undergone gastroscopy during December 2012 to May 2019 were enrolled, and the detection rate of GP and related pathologic data were analyzed. Results: It revealed that 3 858 patients had GP, with a detection rate of 10.47%. In patients over 60 years old, 1 534 patients were diagnosed as having GP, with a detection rate of 14.75%. Compared with patients in other age groups (<30, 30-39, 40-49, 50-59 years), the constituent ratio of patients with GP diameter ≥2.0 was higher(1.8%)(P<0.05), so was with adenomatous polyps (1.9%) and with intraepithelial neoplasia (2.9%)(P<0.05). The only three cases with high-grade intraepithelial neoplasia were all ≥60 years old. Besides, the constituent ratio of patients ≥60 years old with atrophic gastritis and with intestinal metaplasia were 22.4% and 34.0%, respectively,which were higher than those of patients <60 years old. In contrast, GP patients ≥60 years old had a lower constituent ratio of Helicobacter pylori infection (15.1%), lower than that of patients under 60 years old (P<0.01). Conclusions: In comparison with the population <60 years old, population ≥60 had a higher detection rate of GP. GP patients of ≥60 years old had higher proportion of polyps diameter greater than 2 cm, adenomatous polyps, intraepithelial neoplasia, atrophic gastritis, and intestinal metaplasia. Therefore, more attention should be paid to the detection and pathology examination of GP in elderly patients.

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    Interpretation of the Global Tuberculosis Report 2022 by World Health Organization
    LIANG Chen, YU Jiajia, TANG Shenjie
    Journal of Diagnostics Concepts & Practice    2023, 22 (01): 21-30.   DOI: 10.16150/j.1671-2870.2023.01.004
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    Global Tuberculosis Report 2022 (hereafter referred to as “report”), newly published by the World Health Organization (WHO), states that the coronavirus (COVID-19) pandemic has increased the tuberculosis (TB) disease burden and severely affected global TB prevention and control. In 2021, WHO approved a total of six molecular diagnostic technologies for TB diagnosis and anti-TB drug resistance detection, and three new TB antigen-based skin tests for TB screening were recommended. To reduce the burden on patients and the health system, WHO recommends a 4-month regimen for drug-susceptible TB and four shorter regimens for the treatment of multidrug-resistant/rifampicin-resistant tuberculosis (MDR/RR-TB). In addition, there were 26 drugs for TB treatment in clinical trials, and at least 22 clinical trials evaluating drugs and drug regimens for TB treatment were underway. In 2021, the TB epidemic remains severe in China, with the number of newly diagnosed cases ranking third among the 30 countries. In 2021, a total of 639 548 TB cases and 1 763 deaths were reported nationwide, with an incidence of 45.37/100 000 and a mortality of 0.13/100 000. China has the fourth largest number of MDR/RR-TB patients in the world. However, it is necessary to verify whether the regimens for MDR/RR-TB treatment recommended by WHO are suitable for patients in China.

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    Time-Varying Delay and Quantization Error
    LI Bin (李 斌), WAN Yi-ming (万一鸣), YE Hao (叶 昊)
    Journal of shanghai Jiaotong University (Science)    2011, 16 (5): 513-518.   DOI: 10.1007/s12204-011-1181-9
    Abstract1921)      PDF(pc) (303KB)(3071)       Save
    Abstract:  Problems related to fault detection of
    networked control systems (NCSs) with both uncertain time-varying
    delay and quantization error are studied in this paper. A novel
    model with the form of polytopic uncertainty is given to represent
    the influences of both the time-varying delay and the quantization
    error, and then the reference model based method is used to design
    the residual generator that is robust to both unknown
    network-induced delay and unknown inputs. A numerical example is
    also given to illustrate the merits of the presented method. The
    proposed method can be regarded as an extension of the
    authors' former work, which can only deal with time-varying delay.
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    Development of IT Industry in China in the New Age
    JIANG Ze-min
    Journal of Shanghai Jiaotong University   
    Abstract16937)            Save
    The article explains the role and future trend of IT industry, and states that information technology represented by the internet and computers has brought about the third industrial revolution in history. An important impetus for economic growth in modern times, the IT industry has greatly promoted sustainable development and is profoundly changing mankind’s way of life and production. In discussing the development trend of world IT industry, the article suggests that with potential new breakthroughs in IT technology, the trend of agglomeration and integration of industries has become increasingly obvious, competition of intellectual properties and strandards is intensifying and ubiquitous networks is taking shape. It points out that China should bring into better play the role of IT industry as an “amplifier” in economic growth, a “transformer” in development mode and a “propeller” in industrial upgrading. It is important to follow a policy that emphasizes indepandent innovation, marketdriven approach, open and compatible technologies, integrated and comprehensive application, and serving both military and civil purposes, so that a quantum leap of IT industry will be achieved. China should advance industrialization with IT technologles and promote the IT industry in the course of industrialization in an effort to build an IT industry with Chinese characteristics. Greater efforts should be made to develop such core sectors as microelectronics, computer, software, key components and materials, as well as sectors with international competitiveness, including broadband mobile communication, nextgeneration network and information services. Continued improvement should be made in the policies guiding the development of IT industry with a view to making China a country with a strong IT industry by 2020.
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    Chinese interpretation of Japanese Gastric Cancer Treatment Guidelines 2021 (6th edition) and Ruijin clinical practice
    YAN Chao, LU Sheng, YAN Min, ZHU Zhenggang
    Journal of Surgery Concepts & Practice    2023, 28 (04): 326-354.   DOI: 10.16139/j.1007-9610.2023.04.010
    Abstract984)   HTML23)    PDF(pc) (4954KB)(2995)       Save

    “Japanese Gastric Cancer Treatment Guidelines” have been important guidelines for the treatment of gastric cancer in Japan and worldwide. The English version “Japanese Gastric Cancer Treatment Guidelines 2021 (6th Edition)” published in January 2023 consists of two parts. The first part includes diagnostic and treatment methods, such as surgery, endoscopic resection, chemotherapy, follow-up. The second part addresses clinical issues, including recommendations and explanations for clinical hot topics. This article will provide a Chinese interpretation of the guidelines and briefly introduce our hospital's clinical practice in the diagnosis and treatment of gastric cancer.

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    Interpretation on the report of global stroke data 2022
    TANG Chunhua, GUO Lu, LI Qiong, ZHANG Lili
    Journal of Diagnostics Concepts & Practice    2023, 22 (03): 238-246.   DOI: 10.16150/j.1671-2870.2023.03.06
    Abstract3470)   HTML169)    PDF(pc) (2270KB)(2970)       Save

    In 2022, the World Stroke Organization released two new reports regarding global stroke statistics in the International Journal of Stroke. The reports updated the global incidence and mortality of stroke, evaluated the effects of gender and geographic factors, and provided updated statistics on attributable risk factors associated with stroke. This article briefly interprets the two reports in the context of stroke prevalence and disease burden in China. 2019 Global Burden of Disease Study findings show that stroke remains the second-leading cause of death and the third-leading cause of death and disability combined in the world. From 1990 to 2019, the burden (in terms of the absolute number of cases) increased substantially, with the bulk of the global stroke burden residing in lower-income and lower-middle-income countries. Moreover, people under 70-year-old were observed to have significant increases in stroke prevalence and incidence. The five major risks for stroke globally include high systolic blood pressure, high body mass index, high fasting glucose, environmental particulate matter pollution, and smoking. Stroke prevention and treatment in China are facing great challenges. Stroke has become the leading cause of death and disability among Chinese adults, as well as the leading cause of disability adjusted life year lost. The incidence, prevalence and mortality of stroke in China are geographically high in the north, low in the south and prominent in the central part of the country; the prevalence is higher in rural areas than that in urban areas; the morbidity and mortality rates are higher in men than those in women; the average age of onset is lower than in developed countries; the overall disease burden of ischemic stroke is on the rise, but that of hemorrhagic stroke is on the decline. The awareness of stroke prevention and treatment was low. In conclusion, it is of strategic importance to actively establish a graded stroke prevention and control system that meets the national conditions.

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    Interpretation of Multiple Myeloma Guidelines update (version 2, 2023) of National Comprehensive Cancer Network (NCCN)
    TAO Yi, MI Jianqing
    Journal of Diagnostics Concepts & Practice    2023, 22 (02): 121-126.   DOI: 10.16150/j.1671-2870.2023.02.003
    Abstract1484)   HTML58)    PDF(pc) (1042KB)(2844)       Save

    Multiple myeloma (MM) is the second most common hematological malignancy. With the continuous advent of new drugs, the survival of MM patients has been significantly improved, with a median survival of 7-10 years. However, the overall survival of high-risk MM patients is still less than 3 years, and extending the survival of high-risk MM has always been a hot topic in this field. The National Comprehensive Cancer Network (NCCN) released the 2nd version of the MM guidelines for 2023 (2023. v2). Compared with the 5th edition of the MM guidelines for 2022, the update of this guideline in diagnosis is mainly reflected in the detailed description of high-risk MM in tabular form, including both cytogenetic high-risk factors containing 1q21 gain/amplification and clinical high-risk factors, such as extramedullary disease, renal failure and weakness. In terms of treatment, the updated guideline still emphasizes the importance of autologous hematopoietic stem cell transplantation in the era of new drugs, and indicates that the judgment of whether patients are suitable for transplantation needs to be dynamically adjusted based on the patients’ condition after initial treatment. 2023. v2 upgrades the recommendation of the new generation proteasome inhibitor carfilzomib in initial induction and CD38 monoclonal antibody in maintenance therapy. The combinations of these new drugs with immunomodulatory drug pomalidomide are also listed as the preferred regimens in relapsed patients. The diagnostic techniques for distinguishing high-risk MM and new drugs recommended in the updated guideline are currently available in China, Which greatly enhanc our confidence in the “clinical cure” of MM. A comprehensive interpretation of the 2023. v2 of the guidelines is expected to improve the diagnostic and therapeutic level of clinicians, and further improve the prognosis of China’s MM patient population, especially high-risk patients.

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    Interpretation of the Clinical Practice Guidelines for Non-small Lung Cancer (version 4 and version 5) of 2022 National Comprehensive Cancer Nerwork(NCCN)
    CHEN Guoqun, CAI Jiaodi
    Journal of Diagnostics Concepts & Practice    2023, 22 (01): 8-13.   DOI: 10.16150/j.1671-2870.2023.01.002
    Abstract702)   HTML30)    PDF(pc) (900KB)(2627)       Save

    Lung cancer is the leading cause of cancer-related deaths worldwide, with approximately 1.8 million patients dying of lung cancer each year, accounting for 18.0% of all cancer deaths. Non-small cell lung cancer (NSCLC) is the main type of lung cancer and accounts for more than 85% of all lung cancer patients. In China, more than 700 000 new cases of lung cancer are diagnosed each year, and more than 600 000 patients die of lung cancer, accounting for 21.7% of all cancer deaths. In 2022, the National Comprehensive Cancer Network (NCCN) updated the guidelines for clinical diagnosis and treatment of lung cancer. Compared with the third edition of the guidelines, the fourth edition of the guidelines added the reference significance of ERBB2 (HER2) mutation in the diagnosis and treatment of (NSCLC). The updated content was mainly focused on the detection of HER2 mutation as a standard biomarker and the treatment of patients with HER2 mutation. The detection of HER2 mutation is recommended for patients with metastatic NSCLC. Fam-trastuzumab deruxtecan and trastuzumab emtansine are recommended as second-line treatment options for patients with HER2 mutation. However, both are in clinical trials in China. The treatment strategies for NSCLC patients with HER2 mutations need to be considered comprehensively in light of the actual situation, and more data from domestic trials are needed. The fifth edition of the guidelines expanded the use of nivolumab, marking new progress in the study of immune checkpoint inhibitors.

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    Can Research with Chinese Characteristics be Universally Accessible?
    QU Weiguo
    Contemporary Foreign Languages Studies    2020, 20 (4): 13-26.   DOI: 10.3969/j.issn.1674-8921.2020.04.002
    Abstract279)   HTML1)    PDF(pc) (2000KB)(2622)       Save
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    New knowledge of prophylaxis and treatment about cancer-associated thrombosis
    DING Yongjie, ZHANG Liu, LI Qingyun
    Journal of Diagnostics Concepts & Practice    2023, 22 (04): 323-331.   DOI: 10.16150/j.1671-2870.2023.04.001
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    Cancer-associated thrombosis (CAT) is the second leading cause of death in cancer patients, second only to the progression of the tumor. It leads to extended hospitalization and re-hospitalization, resulting in a serious social medical burden. Tumor-specific gene mutations such as JAK2, ALK, and KRAS mutations are closely related to the risk of CAT in patients with solid tumors. Patients treated with immune checkpoint inhibitors have a high risk of CAT, with a 1-year cumulative incidence rate of 10.86%. Therefore, accurate risk assessment is important. The Khorana risk score (KRS) is the first model to assess CAT risk and has been validated in several studies. The new generation models are based on the improvement of KRS, but they have not yet undergone large-scale external verification, such as the Vienna CAT model, PROTECHT model, and CONKO model. Due to the strong correlation between tumors and CAT, several CAT-related prevention guidelines have been established domestically and abroad. All of these guidelines recommend that patients undergo preventive anticoagulation therapy after tumor surgery. Low molecular weight heparin (LMWH) is the most widely used anticoagulant drug to prevent CAT. New oral anticoagulants (NOAC) are also used to prevent CAT, despite the incidence of hemorrhaging increases, the overall benefits to patients outweigh the risks. The strategy for treating CAT is complex. For patients with non-gastrointestinal tumors, NOAC can be used as a first-line drug, while LMWH is recommended for anticoagulation in patients with gastrointestinal tumors. Since CAT patients receive anticoagulation and anti-tumor therapy at the same time, drug interactions need to be considered to avoid drug-induced bleeding, especially the impact of combined medication on NOAC pharmacokinetics. The ideal length of anticoagulation therapy for CAT remains unclear. Guidelines recommend that patients with CAT should indefinitely continue the anticoagulation therapy after completing 3 to 6 months of initial anticoagulation therapy. Therefore, when determining the course of anticoagulation therapy for cancer patients, physicians should evaluate the risk of recurrence of thrombosis and bleeding, and optimize the treatment plan.

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    Clinical characteristics and risk factor analysis of 118 patients with cerebral venous sinus thrombosis
    LI Lei, WU Xi, DAI Jing, WU Wenman, DING Qiulan, WANG Xuefeng
    Journal of Diagnostics Concepts & Practice    2023, 22 (03): 261-269.   DOI: 10.16150/j.1671-2870.2023.03.09
    Abstract160)   HTML9)    PDF(pc) (991KB)(2342)       Save

    Objective: To analyze the clinical characteristics and thrombotic risk factors of cerebral venous sinus thrombosis (CVST) in Chinese population, in order to provide reference for the clinical diagnosis, prevention and treatment of CVST. Methods: A total of 118 CVST patients who visited the Thrombosis and Hemostasis Clinic of Ruijin Hospital from January in 2015 to December in 2022 were enrolled. The clinical data, imaging characteristics, and thrombotic gene panel were collected, and independent risk factors for thrombosis, recurrence, and multi-site thrombosis in CVST patients were studied through univariate and multivariate logistic regression. Results: Among 118 CVST patients, 88.1% (104/118) patients firstly developed CVST at age younger than 45 years old.It revealed that 57.6% patients (68/118) only suffered CVST once,and 33.1% patients (39/118) experienced thrombotic events at least twice, while 37.3% patients (44/118) suffered multi-site venous thromboembolism (VTE). The superior sagittal sinus was the most common venous sinus to form thrombosis (77/118), and multi-sites of venous sinus were involved simultaneously in 54.2% patients (64/118). The risk factor screening for thrombophilia showed that 70.3% patients (83/118) carried at least one thrombotic risk factor, including 53.3% patients (63/118) with inherited risk factors and 32.2% patients (38/118) with acquired risk factors. The main risk factors for males were anticoagulant protein deficiency (35/66) and antiphospholipid syndrome (5/66), while the risk factors for females mainly included anticoagulant protein deficiency (20/52), pregnancy/postpartum period (11/47), and contraceptive use (5/47). Among 35 patients with unknown risk factors, more than 30% of them experienced recurrent or multi-site thrombosis, and the underlying etiology in these patients still need to be further investigated. Univariate and multivariate logistic regression analysis showed that both inherited risk factors (odds ratio, OR=21.643, 95% confidence interval, CI 9.455-49.544, P<0.0001) and acquired risk factors (OR=10.836, 95% CI 4.306-27.270, P<0.0001) were independent risk factors for the occurrence of CVST. Genetic risk factor (OR=2.270, 95% CI 1.021-5.048, P=0.044) was an independent risk factor for recurrent thrombosis in CVST patients. Conclusions: In Chinese population, CVST is more common in middle-aged and young populations.,with 70.3% patients carrying at least one thrombotic risk factor. Genetic risk factors are the main cause of CVST in China and the detectable rate is 53.3%, which is significantly higher than that (22%) reported abroad. The patients with genetic risk factors have a significantly increased risk of developing CVST or recurrent thrombosis. Identification of thrombotic risk factors, prevention, diagnosis and treatment should be carried out earlier for individuals with high-risk CVST.

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    Interpretation of clinical practice guidelines for myelodysplastic syndrome (version 1, 2023) of National Comprehensive Cancer Nerwork(NCCN)
    SONG Luqian, CHANG Chunkang
    Journal of Diagnostics Concepts & Practice    2023, 22 (02): 116-120.   DOI: 10.16150/j.1671-2870.2023.02.002
    Abstract407)   HTML19)    PDF(pc) (904KB)(2283)       Save

    Myelodysplastic syndrome (MDS) is a diverse and common group of myeloid malignant clonal diseases in the hematologic system, with different classification and grouping, clinical manifestations and natural course, and the iteration of different classification systems and versions in history, resulting distress in the correct diagnosis, classification and treatment options. The National Comprehensive Cancer Network (NCCN) released the first version (2023) of Clinical Practice Guidelines for MDS in September 2022. The guideline is based on the clinical practice and standards of high-level evidence and the latest research progress, and its attracts wide attention from clinicians worldwide. Currently, many clinicians in China have insufficient understanding of MDS, and there is still a certain gap with the international diagnosis and treatment level of MDS. This paper interprets the content of the new guidelines, and compares it with the previous guidelines, in order to provide a reference for the standardized diagnosis and treatment of MDS at the current stage in China.

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    Report on diagnosis and treatment of hemophilia in China 2023
    XUE Feng, DAI Jing, CHEN Lixia, LIU Wei, ZHANG Houqiang, WU Runhui, SUN Jing, ZHANG Xinsheng, WU Jingsheng, ZHAO Yongqiang, WANG Xuefeng, YANG Renchi
    Journal of Diagnostics Concepts & Practice    2023, 22 (02): 89-115.   DOI: 10.16150/j.1671-2870.2023.02.001
    Abstract2622)   HTML76)    PDF(pc) (1494KB)(2219)       Save

    In recent years, China attaches great importance to the prevention and treatment of rare diseases. As one of the representative diseases of rare diseases, management of Hemophilia has made great progress in China. From 1986 to 1989, the National Hemophilia Cooperative Group conducted China's hemophilia epidemiological survey according to the unified method and standard, and the results showed that the prevalence of hemophilia was 2.73/100 000, and there was no statistical difference in prevalence among different regions. In 2014, Meta-analysis showed that the prevalence of hemophilia in China was 2.8/100 000, and in 2018, based on the data of the urban population of Tianjin, the local prevalence of hemophilia was estimated to be 3.09/100 000. With the comprehensive promotion of the construction of hemophilia hierarchical diagnosis and treatment system, China requires that hospitals applying for hemophilia comprehensive management centers and diagnosis and treatment centers must be able to independently carry out screening tests and confirmatory tests related to hemophilia diagnosis. For diagnosis of hemophilia, most laboratories in China usually adopt the one-stage method (coagulation method) based on the activated partial thromboplastin time (APTT) for the determination of coagulation factor activity, but it should be noted that more than two activity detection methods are required for some special types of hemophilia. The types of each mutation in the F8 gene of patients in China are similar to those reported in international data, and the mutations in the F9 gene of our patients are mainly single base point mutations, with no mutation hotspots found. As of June 2023, a total of more than 40 000 cases with inherited bleeding disorders registered in 261 centers in China (including hemophilia), through the National Hemophilia Registration System. The history of hemophilia treatment in China has been explored through inadequate on-demand and low-dose prophylaxis, and is now moving towards higher-dose prophylaxis and individualized prophylaxis with higher efficacy. Based on the above registry data and literature, this report comprehensively summarizes the progress of basic and clinical research and medical protection in the field of hemophilia in China, and analyzes the shortcomings for further improvement of hemophilia diagnosis and treatment in China.

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    Fault Detection in Power Distribution Systems Based on Gated Recurrent Attention Network
    CHEN Haolan, JIN Bingying, LIU Yadong, QIAN Qinglin, WANG Peng, CHEN Yanxia, YU Xijuan, YAN Yingjie
    Journal of Shanghai Jiao Tong University    2024, 58 (3): 295-303.   DOI: 10.16183/j.cnki.jsjtu.2022.091
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    To improve fault identification accuracy in power distribution systems, a model named gated recurrent attention network is proposed. First, a higher weight is put on the key cycles of fault phase based on the attention mechanism, making the model focus more on these key messages by weight assignment. Then, the gated recurrent network is adopted, which controls the memory transmission with gate signal and constructs the relationship between input waveform and probability of events at different stages to process the waveform sequence, thereby improving recognition accuracy. Experiments based on both simulation and field data show that the proposed method, under the small-sample-learning condition, is much better than other commonly-used classification models, such as support vector machine, gradient boosting decision tree, and convolutional neural network, providing new insights into fault identification technology in power distribution systems.

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    Advances in surgical treatment of hepatocellular carcinoma
    HUANG Jiwei, QIU Guoteng, ZENG Yong
    Journal of Surgery Concepts & Practice    2022, 27 (02): 113-118.   DOI: 10.16139/j.1007-9610.2022.02.005
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    Association between 24-h ambulatory blood pressure variability and cardiac structure and function
    XU Tingyan, YANG Yan, LI Jingjing, ZHANG Dongyan, WANG Ying, WANG Jiguang, LI Yan
    Journal of Diagnostics Concepts & Practice    2019, 18 (2): 193-198.   DOI: 10.16150/j.1671-2870.2019.02.014
    Abstract463)   HTML0)    PDF(pc) (605KB)(1993)       Save

    Objective: To investigate the association between 24-h ambulatory blood pressure variability and cardiac structure and function in untreated patients. Methods: The association between 24-hour ambulatory blood pressure (BP) recordings and echocardiography in 80 untreated patients referred to a hypertension clinic was assessed. BP variability indices were standard deviation (SD), coefficient of variation (CV), variability independent of the mean (VIM), maximum-minimum difference (MMD), and average real variability (ARV). Effect sizes (standardized β)and partial coefficient of determination were computed using multivariable regression models. Results: Left ventricular mass index(LVMI) (systolic BP: β=6.8—8.0, P<0.01; diastolic BP: β=6.7—7.8, P<0.01), longitudinal strain(LS) (systolic BP: β=-0.76—-0.71, P<0.05; diastolic BP: β=-0.81—-0.71, P<0.05) and septal E/e' (systolic BP: β=0.44—0.57, P<0.05) were associated independently with BP, whereas the association with BP variability was not significant except for those of LVMI with systolic BP CV and VIM ( β=3.3, P=0.048, β=3.4, P=0.049), and of septal E/e' with diastolic BP MMD ( β=0.46, P=0.034). Conclusion: Short-term 24-h blood pressure variability is associated with cardiac structure and function, but blood pressure might be a major factor affecting these cardiac indices.

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    Interpretation of the 2022 edition of “guidelines for diagnosis and management of hyperthyroidism and other causes of thyrotoxicosis in China”
    XU Bojin, PENG Wenfang, HUANG Shan
    Journal of Surgery Concepts & Practice    2023, 28 (06): 512-519.   DOI: 10.16139/j.1007-9610.2023.06.05
    Abstract480)   HTML3)    PDF(pc) (889KB)(1937)       Save

    “Guidelines for diagnosis and management of hyperthyroidism and other causes of thyrotoxicosis in China” (2022) (referred to as the “guidelines”) was officially published in August 2022 in the Chinese Journal of Endocrine Metabolism. These guidelines have been extensively updated from the 2007 version, with 15 sections covering the etiology, clinical manifestations, diagnosis, evaluation, and treatment of hyperthyroidism, as well as the management of specific types of thyrotoxicosis. The new version guidelines proposed 107 recommended opinions supported by stronger evidence, offering comprehensive and reliable guidance for clinical doctors and medical professionals dealing with thyrotoxicosis. This article aimed to extract the key points and recommended strategies from the guidelines to help clinical doctors better understand and apply the latest guiding principles.

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    Journal of Diagnostics Concepts & Practice    2021, 20 (04): 349-355.   DOI: 10.16150/j.1671-2870.2021.04.004
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    The Overall Approach to Studying Translator Groups:A Review of A Study on English Translators of Jiangsu Classic Literature
    FENG Quangong
    Contemporary Foreign Languages Studies    2022, 22 (1): 153-160.   DOI: 10.3969/j.issn.1674-8921.2022.01.013
    Abstract343)   HTML24)    PDF(pc) (1396KB)(1800)       Save

    Nowadays translator studies are greatly emphasized and a large number of relevant research achievements are produced. However, studies on translator groups are relatively few, which should be strengthened in the future. Xu Duo’s monograph A Study on English Translators of Jiangsu Classic Literature, as a typical achievement of studies on translator groups, investigates the translation views, cultural position, translation motives, translation selection and translation features of five translators of Jiangsu classic literature like David Hawkes, John Minford, Moss Roberts, Sidney Shapiro and Yang Xianyi. This paper discusses the overall approach on the study of translator groups mainly by analyzing and commenting on Xu Duo’s monograph, such as the selection of research object and methods, the progression of research blueprint, the realization of research conclusion and so on. It is suggested that emphasis be placed on the investigation of shared features of translator groups and the light shed by translator group studies on current translation practice.

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    Development of Light Photoelectric Guided Missile
    LI Jiatai, CHEN Guoliang, MA Shanbin, WU Zhipeng, WANG Qinchao
    Air & Space Defense    2021, 4 (4): 37-43.  
    Abstract426)      PDF(pc) (5173KB)(1624)       Save
    With the rapid development of new photodetectors, optical materials, signal processing and MEMS techno-logy, the photoelectric precision guidance technology has gradually become one of the most important technologies in the field of precision guidance today, and also lays the foundation for the development of a new generation of light photoelectric guided missile. In this paper, the typical models of light photoelectric guided missile in foreign military are summarized, and the technology development status is introduced. The key technologies in missile overall design technology, detection guidance and control technology, fuse-warhead coordination technology, and motor system technology are analyzed in detail. Finally, the paper envisages the development trend of light photoelectric guided missile.
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    Value of proton and heavy ion radiotherapy in treatment of retroperitoneal sarcoma
    WANG Zheng, BAO Cihang, JIANG Guoliang
    Journal of Surgery Concepts & Practice    2022, 27 (06): 506-510.   DOI: 10.16139/j.1007-9610.2022.06.05
    Abstract329)   HTML14)    PDF(pc) (826KB)(1555)       Save
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    Review of Research on Condition Assessment of Nuclear Power Plant Equipment Based on Data-Driven
    XU Yong, CAI Yunze, SONG Lin
    Journal of Shanghai Jiao Tong University    2022, 56 (3): 267-278.   DOI: 10.16183/j.cnki.jsjtu.2021.502
    Abstract3966)   HTML321)    PDF(pc) (1383KB)(1477)       Save

    The condition assessment of the entire life cycle of nuclear power equipment has a significant impact on improving the safety and economy of nuclear power plants. In the past, operation and maintenance of systems, equipment, and structures of domestic nuclear power plants, mostly relied on the alarm mechanism of equipments, the simple threshold judgments of parameters, or the empirical judgments of engineers. With the implementation of online monitoring system in nuclear power plants, a large number of equipment operation data have been accumulated, and the use of data-driven technology to assess the health of equipment has become the focus of attention in the industry. In this paper, the current situation of the online monitoring system of nuclear power equipment was introduced and the common malfunction of nuclear power equipment was analyzed. The condition assessment of nuclear power equipment were categorized into three major problems (i.e., anomaly detection, life prediction, and fault diagnosis), the situation of research and application were summarized respectively, and the application potential of deep learning technology in this field was emphasized. Based on this, the challenges and possible solutions to the condition assessment of nuclear power plant equipment were further analyzed.

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    Modeling and Stability Analysis of a Pressure Compensator for Flow-Control Valve
    JIA Wen-Hua- , YIN Chen-Bo
    Journal of Shanghai Jiaotong University    2011, 45 (04): 561-564.  
    Abstract5696)            Save
    The forces acting on the load-sensing compensated valve were illustrated and analyzed, the mathematical model was generated using classical momentum principles, while the linear analysis of this was carried out using the Taylor expansions. The valve motion of the system was described by presenting the equation of motion, the stability condition was given by Routh-Hurwitz stability criterion and the dynamic properties of the compensator were studied. The CFD analysis of the compensator was described to study the effect of the force acting on the bottom of the compensator. The pressure along the bottom wall was noted and its variation was plotted against the geometrical position of the bottom wall that it acted on. Noted that this pressure remain constant along the wall. Then, some plots describe the flow induced forces and coefficients used to understand the stability of the compensator itself.
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    Lung cancer worldwide and in China from 1990 to 2020: prevalence and prevention measures
    WANG Zezhou, ZHENG Ying
    Journal of Diagnostics Concepts & Practice    2023, 22 (01): 1-7.   DOI: 10.16150/j.1671-2870.2023.01.001
    Abstract1237)   HTML42)    PDF(pc) (946KB)(1362)       Save

    From 1990 to 2020, the number of newly diagnosed cases of lung cancer in the world continued to grow, but the prevalence remained stable. As time went, the incidence (world standard incidence, adjusted with age structure of world population) of lung cancer changed in gender, region, age, and histological type. The difference between male and female in incidence continued to narrow, with male incidence declining by 12.5% and female incidence rising by 22.3%. There were obvious regional differences in the incidence of lung cancer. From 1998 to 2012, the incidence of male lung cancer in Europe, Asia and North America showed a downward trend (the average annual change percentages were -1.6%, -0.6% and -2.5%, respectively), while the incidence of female lung cancer showed a upward trend except North America. From 1998 to 2012, the average age of lung cancer patients in all regions of the world showed a trend of increasing year by year. The average age at diagnosis of lung cancer in Asian men increased from 67.21 years in 1998 to 69.14 years in 2012. Patterns of histological types of lung cancer have also changed. Since the early 1980s, the proportion of squamous cell lung cancer has declined. Since 2004, adenocarcinoma has become the most common histological type of lung cancer in the world. In 2020, China had the largest cases of newly diagnosed lung cancer in the world. From 1989 to 2008, urban-rural ratio of lung cancer incidence dropped from 2.07 to 1.14. In economically underdeveloped areas, the incidence of lung cancer was also rising, and the situation in some areas with high incidence of lung cancer had been controlled. China, as the largest tobacco producer and consumer country, has to be serious with the control of tobacco. Risk of lung cancer caused by environmental pollution is gradually lower. Controlling occupational exposure is also the key to preventing lung cancer in China, and establishing a mornitoring network for risk factors is the direction in future.

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    Dynamics Modeling and Validation of Coaxial Lifting Rotors
    HU Jinshuo, HUANG Jianzhe
    Journal of Shanghai Jiao Tong University    2022, 56 (3): 395-402.   DOI: 10.16183/j.cnki.jsjtu.2021.044
    Abstract4206)   HTML108)    PDF(pc) (2567KB)(1350)       Save

    The dynamics model for coaxial lifting rotors can be used to study the controller design and flight simulation for coaxial-rotor aerial vehicles. However, both the computational efficiency and the accuracy should be considered. First, the computational model of the induced velocity of lifting rotor everywhere including the wake region is derived based on adjoint theorem. Then, the finite state dynamics model for coaxial lifting rotors with wake skew considered is developed by extending the finite state inflow model for single rotor. Finally, the equations for calculating the thrust of coaxial lifting rotors in the hover condition are given, and the test is conducted. The results show that the computational complexity of the proposed dynamics model for coaxial lifting rotors is acceptable, and the computational thrusts are almost close to the test results when the rotational speed is within a certain range, which can also reflect the trend of the thrust lost for coaxial lifting rotors.

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    Analysis of Combat Concept of "Mosaic Warfare" and Countermeasures
    ZHAO Renxing, WANG Ling, FENG Mingyue, JIA Wentong
    Air & Space Defense    2021, 4 (3): 48-54.  
    Abstract987)      PDF(pc) (3355KB)(1348)       Save
    The US military’s "Mosaic Warfare" combat concept from the perspectives of military strategy, combat theory, and battlefield application are summarized in this article. It has the characteristics of clear directionality, distinct inheritance, and outstanding innovation. It concludes that its combat concept and concept may be important to our combat system. Target protection, the seizure of electromagnetic power, and the suddenness of war have had an impact. On this basis, countermeasures and suggestions have been put forward in terms of combat theory, power building, equipment development, and application of tactics to deal with the challenges of the US military’s "Mosaic Warfare".
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    The fifth edition of WHO classification of digestive system tumors: update and progress on biliary system tumors
    LUO Fangxiu, MA Qianchen, YUAN Fei
    Journal of Surgery Concepts & Practice    2023, 28 (02): 124-131.   DOI: 10.16139/j.1007-9610.2023.02.08
    Abstract773)   HTML20)    PDF(pc) (3365KB)(1341)       Save

    Overall, there was little change in biliary system tumors of the 5th edition of WHO classification of digestive system tumors after update. The three-tiered classification of biliary intraepithelial neoplasia changed to two-tiered system: high-grade and low-grade, in the section of benign tumors and precancerous lesions. And both intracholecystic and intraductal papillary tumors associated with invasive carcinoma were added. The classification of intrahepatic bile duct tumors introduced parts of bile duct adenoma and bile duct adenofibroma, which were mentioned previously in the differential diagnosis with bile duct carcinoma. Intrahepatic cholangiocarcinoma was divided into small bile duct subtype and large bile duct subtype in the 5th edition of WHO classification, and the names of cholangiocellular carcinoma and cholangiole cell carcinoma were no longer recommended to use. Extrahepatic cholangiocarcinoma was listed as a separate part for the first time, including squamous cell carcinoma, adenosquamous carcinoma and undifferentiated carcinoma in addition to common histological types. Some new contents of molecular pathology in the 5th edition of WHO classification were added, which provided the basis for precise classification and diagnosis of tumors in biliary system.

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    John Sinclair's Phrase Theory and Study of Meaning
    PU Jianzhong
    Contemporary Foreign Languages Studies    2021, 21 (6): 60-76.   DOI: 10.3969/j.issn.1674-8921.2021.06.007
    Abstract964)   HTML9)    PDF(pc) (1892KB)(1332)       Save

    This paper aims to discuss John Sinclair's phrase theory and its key concepts, his major contributions to the study of meaning, and the inadequacies as well. It is argued that Sinclair's major achievements in the study of meaning can be attributed to his phrase theory, that its core components are phraseological items and lexical items, that his model of extended unit of meaning, consisting of core, collocation, colligation, semantic preference and semantic prosody, can be applied to the description of both lexical items and phraseological items. Sinclair's major contributions to the study of meaning include that to a great extent he turned the linguists' attention from context to cotext, that he developed and improved the KWIC analysis, upon which the model of extended unit of meaning was formulated, that he put forward the theoretical framework of his phrase theory, getting theoretically ready for the study of meaning. The inadequacies are that the notion of semantic prosody is still vague, preventing the model of extended unit of meaning from being fully exploited, and that paraphrase has not been theoretically evaluated, resulting in language users' meaning not being reflected in his study of meaning.

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    Evaluation of facial injection filling materials for medical aesthetics
    ZHAO Chenyu, LI Chongchong, SUN Xue, et al
    Journal of Tissue Engineering and Reconstructive Surgery    2023, 19 (5): 517-.  
    Abstract213)      PDF(pc) (874KB)(1328)       Save
    With economic development and technological progress, the demand for medical aesthetics has increased sig
    nificantly, and medical biomaterials are widely used. It is necessary to further improve the evaluation of their effectiveness and
    safety. At present, the evaluation of its physicochemical properties and biology is adopted in China. However, the clinical effec
    tiveness is a multi-faceted evaluation without unified criteria. Most of the evaluation mainly adopts objective indicators for quan
    titative analysis, while subjective feelings are secondary criteria. In this paper, the main facial fillers and the evaluation methods
    of their physicochemical properties were reviewed.
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    Elastified Procedure for the Formfound Equilibrium State  and Zero-stress State of Cable-net Structure
    CHEN Wu-Jun, ZHANG Li-Mei, DONG Shi-Lin
    Journal of Shanghai Jiaotong University    2011, 45 (04): 523-527.  
    Abstract5163)            Save
    Six states and five analysis processes were pointed out for the whole numerical analysis process of cable-net structure. The six states are initial geometry state, form-found equilibrium state, elastified form-found equilibrium state, zero-stress (unstressed) state, pre-stress state and loading state, respectively. The five analysis process are form-finding analysis, elastified cable analysis, pre-stress analysis, inverse analysis and loading analysis. And the state parameters were clarified, also for the analytical model of different analysis procedures. The real zero-stress state does not exist generally, the assumed approximated zero-stress state is usually employed. On the basis of elastified form-found equilibrium state, the bestfit reasonable zero-stress state can be found through inverse analysis. The numerical algorithm and procedure was proposed for the ANSYS and EASY for cable-net analysis, and the emphasis is focused on the zero-stress state assumption. Finally, the numerical analysis was exemplified for two cablenet structures. The results demonstrate the significant difference with different zero-stress state assumption and the corresponding numerical analysis approaches.
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    A Review of Coupled Electricity and Hydrogen Energy System with Transportation System Under the Background of Large-Scale New Energy Vehicles Access
    LI Jiaqi, XU Xiaoyuan, Yan Zheng
    Journal of Shanghai Jiao Tong University    2022, 56 (3): 253-266.   DOI: 10.16183/j.cnki.jsjtu.2021.464
    Abstract4322)   HTML963)    PDF(pc) (2106KB)(1313)       Save

    The large-scale utilization of renewable energy is an important way to achieve the “double carbon targets”. The technology of coupled renewable energy with hydrogen system can improve the consumption rate of renewable energy and the penetration of new energy vehicles. The coupling between the electricity-hydrogen energy system and the transportation system will be even closer in the future. Based on the access of large-scale new energy vehicles, first, the development of the electricity and hydrogen energy system was summarized, and the three working modes of electricity-hydrogen coupling system including hydrogen production, output smoothing, and coordinated operation with electricity network were introduced. Then, the research status of the electricity-transportation coupling system on planning and optimal operation, and the problems of hydrogen-transportation coupling system on hydrogen refueling station optimization and hydrogen transportation were analyzed. Finally, in combination with the existing bottlenecks, the future feasible research directions such as dynamic model construction and the influence of uncertain factors were proposed.

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    Effects of Peer Feedback on EFL Learners' Pragmatic Acquisition
    WEI Ran
    Contemporary Foreign Languages Studies    2017, 17 (03): 96-102.   DOI: 10.3969/j.issn.1674-8921.2017.03.017
    Abstract283)      PDF(pc) (1262KB)(1300)       Save
    This study investigated the effects of two types of peer feedback, i.e., peer prompts and peer recasts, on the acquisition of request speech act, i.e., comprehensive and productive acquisition, by 102 non-English majors. Through the experimental design of pretest, posttest, and delayed posttest, it revealed that, peer prompts and peer recasts facilitated learners' pragmatic acquisition in which both experimental groups significantly improved pragmatic comprehensive competence, irrespective of feedback type, while peer prompts group performed significantly better than peer recasts group in pragmatic production. In terms of effect durability, both of them were durable for pragmatic comprehension, but the effect of peer recasts faded away in pragmatic production compared with that of peer prompts.
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    Adaptive Consensus Fusion Estimation for Mobile Sensor Networks
    Wang-Lin, ZHANG Guo-Zhong, ZHU Hua-Yong, SHEN Lin-Cheng
    Journal of Shanghai Jiaotong University    2011, 45 (03): 383-0387.  
    Abstract4531)            Save
    To the problem of distributed estimation for mobile sensor networks(MSN)with communication delays and switching network topologies, a novel distributed fusion estimation algorithm, named adaptive consensus based bistributed unscented information filter(AC_DUIF), was presented. The proposed algorithm was based on unscented information filter, adaptive consensus algorithm, as well as a new fusion framework for the consideration of the communication delays. An application of target tracking using an air mobile sensor networks with dynamically switched network topologies was employed to illustrate the performance of the proposed algorithm. The simulation results show that the proposed method can significantly improve the accuracy of target position estimation of each sensor node in a distributed fashion, when the distributed consensus between each nodes and the adaptability of the communication delays are assured.
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    Low Signature Target Group Detection Based on Multimodal Data Learning Fusion Network
    ZHAO Huipan, LIU Huanyu
    Air & Space Defense    2021, 4 (3): 41-47.  
    Abstract458)      PDF(pc) (6554KB)(1279)       Save
    Low signature target group detection is a difficult problem. With the development of sensor technology, the target detection method based on multimodal data fusion becomes possible. Traditional methods focus on the artificial design of multi-modal data fusion level, by using signal level and decision-making level fusion, and neglecting multi-modal inherent fusion features. In order to make full use of the inherent multimodal feature expression ability of deep convolution network, a point to point multimodal data learning fusion network is proposed, which can fuse data from visible, infrared and Doppler pulse radar data devices. The experimental results on FLIR_ADAS dataset show that the proposed algorithm can significantly improve the performance of low signature target group detection.
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    A Method for Multitarget Passive Location by a Movable Single Station  Based on Weighted MUSIC Algorithm in FRFT Domain
    HE Wei-Yan, JIN Rong-Hong, GENG Jun-Ping, LIANG Xian-Ling
    Journal of Shanghai Jiaotong University    2011, 45 (03): 345-0349.  
    Abstract4470)            Save

    Aiming at the situation of multiple linear frequency modulation(LFM) signal sources, by analyzing the Doppler shift of received signals, a multicomponent LFM signal model for the antenna array on a movable single station was built. Then a method for multitarget passive location based on weighted MUSIC algorithm in fractional Fourier transformation(FRFT) domain was presented, which implements the detection and DOA estimation of multitarget signals at low SNR. The simulation results show that  multiple targets with similar frequency and close space can be distinguished in a high accuracy.
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    An Identification Method for DC-Link Capacitor Capacitance of Grid Connected Inverter
    ZHU Chenghao, WANG Han, SUN Guoqi, WEI Xiaobin, WANG Fuwen, CAI Xu
    Journal of Shanghai Jiao Tong University    2022, 56 (6): 693-700.   DOI: 10.16183/j.cnki.jsjtu.2021.515
    Abstract1086)   HTML1284)    PDF(pc) (5050KB)(1270)       Save

    DC-link for the capacitor is one of the most vulnerable components of the grid connected converter, whose capacitance identification will help to improve the system reliability by finding and replacing the aging capacitor in time. An identification method for the DC-link capacitor capacitance of the grid connected inverter based on pre-charging circuit is proposed. By analyzing the relationship between the capacitance and the charging current, charging voltage during pre-charging process, and combining the historical operating data, the set of capacitance state feature vector is built. The support vector regression (SVR) model is trained and the regression prediction relationship between the state value and the capacitance is set. The model is optimized by using the particle swarm optimization (PSO) algorithm, which can be used for capacitance identification of the DC-link capacitor. Simulation and experiments results show that the proposed method can implement the accurate capacitance identification of the DC-link capacitor of the grid connected inverter, with an identification error of less than 0.95%. This method does not need to add hardware circuit and change the control algorithm, and has a certain practical value.

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