Most Down Articles

    Published in last 1 year | In last 2 years| In last 3 years| All| Most Downloaded in Recent Month | Most Downloaded in Recent Year|

    All
    Please wait a minute...
    For Selected: Toggle Thumbnails
    Research progress of miRNA-206 on lung diseases
    ZHANG Lulu, WU Qiannan, HUO Rujie, et al
    Journal of Internal Medicine Concepts & Practice    2022, 17 (05): 413-417.   DOI: 10.16138/j.1673-6087.2022.05.014
    Abstract164)   HTML5)    PDF(pc) (507KB)(1204)       Save
    Reference | Related Articles | Metrics | Comments0
    Journal of Internal Medicine Concepts & Practice    2021, 16 (03): 220-224.   DOI: 10.16138/j.1673-6087.2021.03.018
    Abstract266)   HTML5)    PDF(pc) (531KB)(1166)       Save
    Reference | Related Articles | Metrics | Comments0
    Journal of Internal Medicine Concepts & Practice    2022, 17 (04): 344-348.   DOI: 10.16138/j.1673-6087.2022.04.015
    Abstract272)   HTML10)    PDF(pc) (526KB)(802)       Save
    Reference | Related Articles | Metrics | Comments0
    Value of serum N-terminal pro-brain natriuretic peptide levels in primary screening peritoneal dialysis patients with volume overload
    LI Hua, HUANG Xiaomin, ZHANG Chunyan, DU Lu, REN Hong, XU Tian
    Journal of Internal Medicine Concepts & Practice    2023, 18 (03): 157-164.   DOI: 10.16138/j.1673-6087.2023.03.005
    Abstract571)   HTML1)    PDF(pc) (845KB)(757)       Save

    Objective To explore the relationship between serum N-terminal pro-brain natriuretic peptide (NT-proBNP) level and hydration status and cardiac function indexes in the patients receiving peritoneal dialysis(PD) treatment,and to further analyze the factors affecting the level of NT-proBNP. Methods A total of 111 patients with PD who were followed up in the PD Center of Ruijin Hospital, Shanghai Jiao Tong University School of Medicine from May 2019 to January 2022 were enrolled and the data was analyzed retrospectively. According to the results of multi-frequency bioelectrical impedance body composition monitor (BCM), relative hydration status (DHS), the ratio obtained through dividing extracellular water (ECW) by overhydration (OH), the patients were divided into normal volume group (OH/ECW≤15%) and overhydration group (OH/ECW>15%). The relationship between serum NT-proBNP level and hydration status in two groups was compared, and the related factors affecting the level of NT-proBNP were further analyzed and discussed. Using BCM result as the“gold standard”, the receiver operator characteristic curve(ROC curve) determined the optimal threshold of NT-proBNP as the capacity was overloaded. The patients were divided into two groups according to NT-proBNP and their clinical data were compared. Results The indexes including systolic blood pressure, urine volume, urea clearance index (Kt/V), creatinine clearance rate(CCr), dialysate to plasma ratio for urea at 4 hours(4hD/PCr), types of antihypertensive drugs, type of diuretic, hemoglobin, serum albumin, log2(NT-proBNP), interventricular septal thickness (IVST), left ventricular posterior wall thickness(LVPWT), left atrial diameter(LAD), OH, TBW, ECW, OH/TBW, ECW/TBW and ECW/ICW were detected in volume overload group and normal volume group, and showed statistically significant (all P<0.05). log2(NT-proBNP) level was correlated with systolic blood pressure, dialysis duration, ultrafiltration volume, dialysis dose, antihypertensive drug group, IVST, LVPWT, LAD, left ventricular end-systolic dimension (LVESD), left ventricular end-diastolic dimension (LVEDD), OH, OH/ECW were positively correlated (all P<0.05). It was negatively correlated with urine volume, Kt/V, CCr, normalized protein catabolic rate (nPCR), hemoglobin, serum albumin and LVEF (all P<0.05). NT-proBNP 4 896 ng/L could be used as the critical value of initial screening capacity overload and was applied to divide the patients into two groups, and the systolic blood pressure, urine volume, ultrafiltration volume, Kt/V, CCr, IVST, LVPWT, OH/ECW indicators showed significant differences (all P<0.05) in two groups. Conclusions The level of NT-proBNP in PD patients is generally increased, and it indicates volume overload as its value is greater than 4 896 ng/L, which can be used as a simple monitoring index for the preliminary judgment of volume overload in PD patients.

    Table and Figures | Reference | Related Articles | Metrics | Comments0
    Novel coronavirus infection: a new challenge for the management of thyroid disease
    XIANG Pingping, LIU Chao
    Journal of Internal Medicine Concepts & Practice    2022, 17 (06): 486-490.   DOI: 10.16138/j.1673-6087.2022.06.013
    Abstract154)   HTML2)    PDF(pc) (531KB)(701)       Save
    Reference | Related Articles | Metrics | Comments0
    COVID-19 vaccine induced thyroid disease: challenges and strategies
    YUAN Li, XIANG Pingping, CHEN Guofang, et al
    Journal of Internal Medicine Concepts & Practice    2023, 18 (02): 121-123.   DOI: 10.16138/j.1673-6087.2023.02.012
    Abstract293)   HTML13)    PDF(pc) (310KB)(659)       Save
    Table and Figures | Reference | Related Articles | Metrics | Comments0
    Journal of Internal Medicine Concepts & Practice    2021, 16 (06): 438-441.   DOI: 10.16138/j.1673-6087.2021.06.015
    Abstract183)   HTML5)    PDF(pc) (485KB)(556)       Save
    Reference | Related Articles | Metrics | Comments0
    Journal of Internal Medicine Concepts & Practice    2021, 16 (05): 289-293.   DOI: 10.16138/j.1673-6087.2021.05.001
    Abstract353)   HTML8)    PDF(pc) (662KB)(536)       Save
    Table and Figures | Reference | Related Articles | Metrics | Comments0
    Geometric deep learning and computational medicine research prospects of “preventing disease” in pre diabete
    RUAN Ming, HOU Tianzhichao, WANG Haiyan, et al
    Journal of Internal Medicine Concepts & Practice    2022, 17 (06): 475-481.   DOI: 10.16138/j.1673-6087.2022.06.011
    Abstract357)   HTML6)    PDF(pc) (830KB)(467)       Save
    Reference | Related Articles | Metrics | Comments0
    Journal of Internal Medicine Concepts & Practice    2022, 17 (03): 202-207.   DOI: 10.16138/j.1673-6087.2022.03.006
    Abstract331)   HTML7)    PDF(pc) (711KB)(456)       Save
    Table and Figures | Reference | Related Articles | Metrics | Comments0
    Journal of Internal Medicine Concepts & Practice    2022, 17 (01): 92-96.   DOI: 10.16138/j.1673-6087.2022.01.018
    Abstract158)   HTML1)    PDF(pc) (521KB)(456)       Save
    Reference | Related Articles | Metrics | Comments0
    Journal of Internal Medicine Concepts & Practice    2022, 17 (02): 117-122.   DOI: 10.16138/j.1673-6087.2022.02.004
    Abstract246)   HTML6)    PDF(pc) (1631KB)(431)       Save
    Table and Figures | Reference | Related Articles | Metrics | Comments0
    Journal of Internal Medicine Concepts & Practice    2021, 16 (01): 53-59.   DOI: 10.16138/j.1673-6087.2021.01.012
    Abstract287)   HTML13)    PDF(pc) (774KB)(423)       Save
    Table and Figures | Reference | Related Articles | Metrics | Comments0
    Progress in clinical application of leadless pacemaker
    TANG Baopeng, ZHANG Jianghua, GUO Yankai
    Journal of Internal Medicine Concepts & Practice    2022, 17 (05): 365-368.   DOI: 10.16138/j.1673-6087.2022.05.003
    Abstract209)   HTML5)    PDF(pc) (426KB)(418)       Save
    Reference | Related Articles | Metrics | Comments0
    Journal of Internal Medicine Concepts & Practice    2022, 17 (03): 258-261.   DOI: 10.16138/j.1673-6087.2022.03.017
    Abstract522)   HTML26)    PDF(pc) (363KB)(416)       Save
    Reference | Related Articles | Metrics | Comments0
    Application of pulsed electric field ablation in atrial fibrillation
    ZHANG Zhi, TANG Xuechao, HUANG Xinmiao, et al
    Journal of Internal Medicine Concepts & Practice    2022, 17 (05): 400-404.   DOI: 10.16138/j.1673-6087.2022.05.011
    Abstract198)   HTML4)    PDF(pc) (593KB)(393)       Save
    Table and Figures | Reference | Related Articles | Metrics | Comments0
    Expert consensus on diagnosing and evaluating sacroiliitis using magnetic resonance imaging
    DAI Shengming, BAO Chunde, ZOU Hejian, et al
    Journal of Internal Medicine Concepts & Practice    2023, 18 (02): 65-69.   DOI: 10.16138/j.1673-6087.2023.02.001
    Abstract758)   HTML16)    PDF(pc) (756KB)(344)       Save
    Table and Figures | Reference | Related Articles | Metrics | Comments0
    Reliability and validity of the ultra-brief screening scale for depression and anxiety in outpatients clinics of community healthcare centers
    QIAN Jie, JIANG Minmin, CHEN Chen, CHEN Yujiao, YU Dehua, LI Chunbo
    Journal of Internal Medicine Concepts & Practice    2021, 16 (02): 116-120.   DOI: 10.16138/j.1673-6087.2021.02.010
    Abstract512)   HTML12)    PDF(pc) (516KB)(334)       Save

    Objective To preliminary evaluate the reliability and validity of the ultra-brief screening scale for depression and anxiety [patient health questionnaire 4 (PHQ-4)] in outpatients clinics of community healthcare centers. Methods Totally 313 patients were randomly selected from two community healthcare centers in Shanghai. The patients were asked to complete the PHQ-4 following the prescribed instruction with assistance of a psychiatrist and two physicians, and then were evaluated according Hamilton depression scale(HAMD) and the Hamilton anxiety scale(HAMA) followed by a mini international neuropsychiatric interview(MINI). Out of subjects screened, 50 patients were randomly selected to retest the PHQ-4. The reliability coefficients, retest reliability and criterion validity sensitivity and specificity were calculated. The receiver operating characteristic(ROC) analysis was performed to determine the best cut-off value, and the sensitivity and specificity accordingly. Results The Cronbach’α coefficient of PHQ-4 was 0.833, the Spearman-Brown coefficient of the split-half reliability was 0.835. For the test-retest reliability, the intraclass correlation coefficient (ICC) was 0.969. The correlation coefficients of generalized anxiety disorder 7(GAD-7) with HAMD and HAMA were 0.391 and 0.407 respectively, both statistically significant (P<0.01). ROC analysis showed that the area under curve(AUC) was 0.919, and the best cut-off value was 3, the sensitivity and specificity of PHQ-4 were 87.1% and 82.6% respectively. Conclusions The Chinese version of the PHQ-4 maintains high reliability and validity in outpatient clinics of community healthcare centers, and is suitable for the screening of depression and anxiety.

    Table and Figures | Reference | Related Articles | Metrics | Comments0
    Journal of Internal Medicine Concepts & Practice    2022, 17 (01): 15-23.   DOI: 10.16138/j.1673-6087.2022.01.004
    Abstract274)   HTML10)    PDF(pc) (1128KB)(320)       Save
    Table and Figures | Reference | Related Articles | Metrics | Comments0
    An update on complement targeted treatment of IgA nephropathy
    ZHANG Huijian, LI Guisen
    Journal of Internal Medicine Concepts & Practice    2023, 18 (03): 197-200.   DOI: 10.16138/j.1673-6087.2023.03.013
    Abstract536)   HTML14)    PDF(pc) (481KB)(319)       Save
    Table and Figures | Reference | Related Articles | Metrics | Comments0