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    CSSVA Guidelines for Vascular Anomalies 2019
    Journal of Tissue Engineering and Reconstructive Surgery    2019, 15 (5): 277-317.   DOI: 10.3969/j.issn.1673-0364.2019.05.001
    Abstract2532)            Save
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    Journal of Tissue Engineering and Reconstructive Surgery    2007, 3 (1): 55-56.   DOI: 10.3969/j.issn.1673-0364.a173
    Abstract2019)            Save
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    Biomechanical Analysis of a Modification of Tang Method and Its Application on Flexor Tendon Repair in Zone Ⅱ
    SONG Nan,MAO Hailei,YANG Xi,XU Qiming,JIANG Yongkang,ZHOU Shengbo,NI Feng,WANG Bin
    Journal of Tissue Engineering and Reconstructive Surgery    2014, 10 (4): 211-214.   DOI: 10.3969/j.issn.1673-0364.2014.04.011
    Abstract1654)            Save
    Objective To investigate the biomechanical properties and preliminary application of a new suture method, modification of Tang's method, for flexor tendon repair. Methods Thirty-six fresh porcine flexor tendons were divided and repaired with either the modified Tang or the original Tang method. The tendons were subjected to linear or 90 ° angular loading in an Instron tensile testing machine. 2 mm gap formation force and ultimate strength were recorded. M-Tang method was performed in repairing 96 human flexor tendons in zone Ⅱ, and protected passive and active motion protocol were used in eash case after the operation. Strickland TAM classification was applied to evaluate the function postopertively. Results Under linear tension mode, M-Tang was similar to Tang method with its 2 mm gap formation force at (46.2 ±5.2) N, ultimate strength at (61.9 ±6.0) N; Under angular tension mode, M-Tang was similar to Tang with its 2 mm gap formation force at (35.9±3.6) N, but superior to Tang with its ultimate strength at (57.0±4.5) N. No tendon rupture was observed in any of the repaired fingers. Strickland TAM classification showed excellent in 78 cases, good in 10 cases, fair in 8 cases, and the total good rate was 91.6%. Conclusion M-Tang method maintained the biomechanical characters of the original Tang method which can fulfill the requirements for early motion protocol. With fewer suture and knots and easy to operate, M-Tang method was one of the first choice in repairing flexor tendons in zone Ⅱ.
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    Overview and Research Progress of microRNA
    QI Bin,YU Limei,Zunyi Medical college,
    Journal of Tissue Engineering and Reconstructive Surgery    2014, 10 (6): 357-359.   DOI: 10.3969/j.issn.1673-0364.2014.06.016
    Abstract1518)            Save
    The microRNA is only 20-22 nucleotides in length and can work as post-DNA transcription regulator for gene expression. It has an important regulating role in the life process such as cell aging, disease and so on. So microRNA has a huge potential for anti-aging and disease treatment. Nowadays it has become one of the most intense interests to the tissue engineering and other area of medicine. In this paper, the biogenesis, mechanism, relationship with cell aging and age-associated diseases and the clinical application of microRNA were reviewed.
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    Research Progress of SVF Isolation and Clinical Application
    SUN Sijie
    Journal of Tissue Engineering and Reconstructive Surgery    2018, 14 (6): 353-356.   DOI: 10.3969/j.issn.1673-0364.2018.06.015
    Abstract1504)            Save
    Stromal vascular fraction(SVF)is a heterogeneous collection of cells,which is the remaining ingredients after removing mature fat cells in the adipose tissue of transplantation.SVF includes adipose-derived stem cells(ADSCs),hematopoietic stem cell,endothelial precursor cells,macrophages,etc.ADSCs have multipotent differentiation capacity and can release of various cytokines thus show promise in regenarative and reconstructive medicine.The methods for acquiring SVF mainly include enzymatic and mechanical isolation,which have not reached a wide consensus.SVF has been widely used in plastic surgery including enhancing the viability of fat grafts,skin rejuvenation,treatment of facial scars and alopecia,etc.SVF is also comparably effective in several human diseases including radiation injuries,osteoarthritis,diabetes and so on.But there is still debate with regards to safe and efficacious use of SVF.Further studies are needed to investigate the optimal procedures for efficient SVF isolation,elucidate its characterization and discover newer applications apart from the plethora already identified.
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    Application of Autologous Concentrated Growth Factor (CGF) in Treating Androgenetic Alopecia (AGA): 20 Cases
    TAN Pohching,ZHOU Shuangbai,WU Wei,LIU Kai,XIE Yun,LI Qingfeng
    Journal of Tissue Engineering and Reconstructive Surgery    2019, 15 (3): 159-184.   DOI: 10.3969/j.issn.1673-0364.2019.03.008
    Abstract1408)            Save
    Objective To explore the clinical effect of Concentrated Growth Factor(CGF)in treating Androgenetic Alopecia(AGA).Methods Twenty cases of AGA patients were treated with subcutaneous injection of CGF in alopecia area and were followed up for at least 12 weeks after treatment.The effectiveness were evaluated before and after treatment for 4,8,12 weeks.The efficacy of the treatment was comprehensively evaluated by digital photographs,Global Aesthetic Improvement Scale(GAIS)scale,trichoscopy images and the patient satisfaction questionnaire.The safety of the treatment was evaluated by observing the signs of infection,swelling or ulceration in the injection area.Results Gross photographs showed that the hair coverage increased significantly and the appearance of hair loss improved after the injection of CGF.The GAIS score suggested that CGF was effective for the management of AGA.The hair density and the ratio of terminal hair/vellus hair(T/V ratio)were increased showed by trichoscopy images.The patients'satisfaction rate was 85%.No side effects was observed during the follow-up period.Conclusion CGF is a safe and effective method for the treatment of androgenic alopecia.It is easier to produce and master and may be used as a novel therapy for the management of AGA.
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    Application of Mini Camera GoPro Hero 4 in Video Capture of Plastic and Reconstructive Surgery Procedures
    CHEN Chuhsin,LIU Kai
    Journal of Tissue Engineering and Reconstructive Surgery    2017, 13 (2): 98-101.   DOI: 10.3969/j.issn.1673-0364.2017.02.012
    Abstract1127)            Save
    Objective To explore the application of GoPro in recording plastic surgery for documentary and tutorial purposes, thus obtaining optimal parameters for operative shoots. Methods The GoPro HERO 4 Silver Edition camera was head-mounted on the surgeon and oriented to the surgeon's perspective using the GoPro App. The camera was used to record:hemangioma interventional surgery (1 case), nasal reconstruction procedure (1 case), pouch resection (1 case) and rhinoplasty with autologous ear cartilage graft (1 case). During case 3, the surgeon was equipped with an additional headlamp. For case 4 the GoPro was mounted with a macro lens to zoom up close on the surgical field. Results Camera settings for case 1 were as follows: 1080 p video resolution; 60 fps; low-light mode on; narrow field of view; 16:9 aspect ratio. The intervention display screen shown in the footage was overexposed. Within case 2 to case 4, the parameters mentioned above were adjusted to a narrow field of view, which enabled the camera's automatic white balance to better compensate for bright lights focused on the surgical field. The video captured in Case 2 was adequate for teaching or presenting. During case 3 the lighting contrast resulted in limited exposure due to the headlamp. For case 4, macro photography captured more details. Conclusion The GoPro HERO 4 Silver Edition camera enables high-quality, cost-effective video recording of plastic and reconstructive operation. When set to a narrow field of view and automatic white balance, the camera is able to sufficiently compensate for the contrasting light environment of the operating room and capture high-resolution and detailed video.
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    Progress of Diagnosis and Treatment of Verrucous Venous Malformation
    Lili QIAN, Yajing QIU,
    Journal of Tissue Engineering and Reconstructive Surgery    2020, 16 (3): 210-213.   DOI: 10.3969/j.issn.1673-0364.2020.03.009
    Abstract1083)   HTML253)    PDF(pc) (766KB)(918)       Save
    Verrucous venous malformation, formerly known as verrucous hemangioma, is a rare congenital vascular abnormality. It usually appears at birth or in early childhood. It enlarges with body growth and does not regress spontaneously. The early lesions are red in color, with clear boundaries. But in time they become increasingly hyperkeratotic and verrucous. It is generally accepted that surgical excision is the first choice of treatment. The incomplete excision would lead to recurrence of the lesion from the deeper components. Cryosurgery, electrocautery, laser therapy or sclerotherapy can be used to combine with surgical resection, to prevent recurrence or delay the development of lesions. In this paper, the diagnosis and treatment of verrucous venous malformation were reviewed, in order to guide the clinical diagnosis and treatment of verrucous venous malformation.
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    Research Progress in Keloid
    WANG Wenbo
    Journal of Tissue Engineering and Reconstructive Surgery    2018, 14 (6): 357-360.   DOI: 10.3969/j.issn.1673-0364.2018.06.016
    Abstract1077)            Save
    Keloid is a kind of dermatosis with connective tissue hyperplasia.Several etiological factors for keloids have been proposed in the past,including genetic predisposition,tension present in the local skin environment and immunoendocrinology factors.However,the pathogenesis of keloid has not been elucidated,and there is no appropriate treatment to get the satisfactory therapeutic effect.At present,comprehensive treatment based on clinical manifestations is mainly applicated to obtain the best therapeutic effect.In this paper,the progress of clinical therapy and pathogenesis of keloids in recent years were reviewed.
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    Effectiveness of Picosecond 755 nm Alexandrite Laser for the Treatment of Melasma
    XIA Xuqiong,ZHENG Rui,SHEN ZhengYu,CHEN Jun
    Journal of Tissue Engineering and Reconstructive Surgery    2017, 13 (4): 201-204.   DOI: 10.3969/j.issn.1673-0364.2017.04.007
    Abstract1049)            Save
    Objective To evaluate the clinical efficacy,safety and recurrence rate of picosecond 755 nm alexandrite laser in the treatment of melasma.Methods All 51 patients with melasma were treated with picosecond 755 nm alexandrite laser combined with a focus lens array for 5 treatment sessions every 3 weeks.The treatment parameter:0.4 J/cm2 of fluence,8 mm of spot size,5 Hz of frequency and 550×10-12 sec of pulse duration.Patients were all followed up for 8 weeks.Outcomes assessments including photography,melasma area and severity index (MASI) score and related adverse reactions were recorded.The factors affecting the treatment were analyzed.Results The mean MASI score decreased dramatically from (12.04±6.54) to (6.82±5.63) after 5 laser treatment sessions,the decreasing ration of the MASI score was about 47.22%.But after 8-week follow up,the mean MASI score slightly increased to (7.67±5.63).No obvious side effect was observed.Through the statistical analysis,disease duration,severity,wood's lights typing,Fiztpatrick typing,and family history of melasma had impact on the prognosis of melasma.Conclusion The novel picosecond 755 nm alexandrine laser is effective and safe with lower recurrence rate in the treatment of melasma,and is worthy of promotion.
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    Research Progress of Animal Models for Cutaneous Wound Healing and Hypertrophic Scar
    ZHOU Sizheng
    Journal of Tissue Engineering and Reconstructive Surgery    2018, 14 (1): 48-52.   DOI: 10.3969/j.issn.1673-0364.2018.01.013
    Abstract1045)            Save
    Cutaneous wound healing and hypertrophic scar are both the research hotspots in plastic surgery. There are a number of animal models for research. However, phylogenetic variation of skin structure between human and other animals hinders the development of optimal animal model. In this paper, the advancement of animal models for cutaneous wound healing and hypertrophic scar was reviewed.
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    Case Report:Crouzon Syndrome
    WANG Jing,YAN Qing,HE Junping,QIU Dezhi,WANG Gang
    Journal of Tissue Engineering and Reconstructive Surgery    2020, 16 (1): 62-64.   DOI: 10.3969/j.issn.1673-0364.2020.01.016
    Abstract1034)      PDF(pc) (3230KB)(1095)       Save
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    Efficacy of Non-Ablative 1540 nm Erbium-Glass Fractional Laser on Facial Post-Acne Lesions
    SHI Yu,ZHANG Wei
    Journal of Tissue Engineering and Reconstructive Surgery    2017, 13 (3): 149-152.   DOI: 10.3969/j.issn.1673-0364.2017.03.009
    Abstract1025)            Save
    Objective To evaluate the clinical efficacy and safety of non-ablative 1540 nm erbium-glass fractional laser on treating facial post-acne lesions, including atrophic scars, enlarged pores, post-acne erythema and post-inflammatory hyperpigmentation (PIH). Methods A non-ablative 1540 nm erbium-glass fractional laser was used to treat 28 patients. All patients were treated for 3-9 times with an interval of 4-week. The efficacy was assessed by A quartile grading scale, VISIA complexion analysis system and CK skin property 1 month after treatment. Results The efficacy rate of non-ablative 1540 nm erbium-glass fractional laser was 14.29% for post-acne scars, 25% for enlarged pores, 34.76% for post-acne erythema and 18.18% for PIH. Compared to pre-therapy, there was significant difference in pores, erythema and purple mass, and there was positive correlation between efficacy and treatment frequencies (P0.05). No severe adverse effect was observed. Conclusion Non-ablative 1540 nm erbium-glass fractional laser was safe and effective in treating post-acne skin lesions, especially for post-acne erythema and enlarged pores.
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    Orthodromic Temporalis Flap Transfer for Late Facial Palsy Reanimation:a Minimal Invasive Procedure
    WANG Wei,YANG Chuan
    Journal of Tissue Engineering and Reconstructive Surgery    2010, 6 (1): 24-27.   DOI: 10.3969/j.issn.1673-0364.2010.01.007
    Abstract975)            Save
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    A Tension-reduced Suture Technique in Scar Plastic Surgery
    CHEN Libin,WU Xiaoli,CHEN Zongan,GAO Zhen
    Journal of Tissue Engineering and Reconstructive Surgery    2019, 15 (2): 63-64.   DOI: 10.3969/j.issn.1673-0364.2019.02.001
    Abstract962)            Save
    Skin tension plays a very important role among a series of factors in scar formation.The tension-reduced suture in scar plastic surgery is directly related to the prognosis of scar excision.Currently,a new type of tension-reduced suture named"fish bone tension-reduction suture technique"is adopted,which can provide effective,convenient and powerful tension-reduction effect during and after the operation,thus greatly reducing the risk of hypertrophic scar formation and achieving a fine line-like scar.
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    Progress in the Treatment of Hypertrophic Scars and Keloids
    MA Qianyu,WU Xiaoli
    Journal of Tissue Engineering and Reconstructive Surgery    2020, 16 (1): 1-5.   DOI: 10.3969/j.issn.1673-0364.2020.01.001
    Abstract944)      PDF(pc) (736KB)(1923)       Save
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    Etiology, Classification and Treatment of Brachydactyly
    YANG Xi,WANG Bin
    Journal of Tissue Engineering and Reconstructive Surgery    2015, 11 (6): 389-395.   DOI: 10.3969/j.issn.1673-0364.2015.06.012
    Abstract944)            Save
    Brachydactyly(BD) is a congenital deformity that refers to shortening of the hands/feet due to small or missing metacarpals/metatarsals and/or phalanges characterized by bone dysostosis. According to Bell's classification, BD can be divided into to five categories: A to E. Recent years, new subtypes were advocated. Among these, BDA3 and BDD may be the most common subtypes. The deformity was close related to familial inheritance and gene mutations. In this review, the advancements in etiology, classification and treatments of brachydactyly were summarized.
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    A Clinical Study of Different Concentrations of Timoiol Maleate Eye Drops for the Treatment of Superficial Infantile Hemangiomas
    Shengmiao LI, Chunfen LUO, Jiachuan XU, Linjun YU
    Journal of Tissue Engineering and Reconstructive Surgery    2020, 16 (3): 179-181.   DOI: 10.3969/j.issn.1673-0364.2020.03.001
    Abstract941)   HTML564)    PDF(pc) (1010KB)(625)       Save

    Objective To explore the efficacy and safety of timolol maleate eye drops with different concentrations for the treatment of superficial infantile hemangiomas.

    Methods From January 2018 to January 2019, patients aged within 6 months with superficial infantile hemangiomas were enrolled, and were randomly divided into 2 groups according to different concentration of timolol maleate eye drops: 0.25% timolol group and 0.5% timolol group. Tiamolol maleate eye drops were applied externally by wet compressing for 20 minutes, three times a day for 6 months. The therapeutic effect was categorized into four grades, the therapeutic effect and safety of the two groups were compared.

    Results A total of 87 patients with superficial infantile hemangiomas were included in the study and were divided into 0.25% timolol group (n=41) and 0.5% timolol group (n=46). Six months after treatment, the effective rate and cure rate of 0.25% timolol group were 63.4% and 14.6%, the effective rate and cure rate of 0.5% timolol group were 82.6% and 19.6%. The effective rate of 0.5% timolol group was significantly higher than that of 0.25% timolol group (P<0.05). There was no significant difference of cure rate between the two groups (P>0.05). No severe systemic or local adverse reactions were observed during treatment.

    Conclusion Topical application of timolol maleate eye drops in the treatment of superficial infantile hemangiomas during proliferative phase is simple, effective and safe. Drug concentration may be one of the factors influencing clinical efficacy.

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    Journal of Tissue Engineering and Reconstructive Surgery    2021, 17 (5): 445-.  
    Abstract936)            Save
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    CSSIV Guidelines for Vascular Anomalies 2024
    Chinese society for the study of vascular anomalies(CSSVA)
    Journal of Tissue Engineering and Reconstructive Surgery    2024, 20 (1): 1-.  
    Abstract921)      PDF(pc) (1759KB)(8094)       Save
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