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    China Alzheimer Report 2024
    WANG Gang, QI Jinlei, LIU Xinya, REN Rujing, LIN Shaohui, HU Yisong, LI Haixia, XIE Xinyi, WANG Jintao, LI Jianping, ZHU Yikang, GAO Mengyi, YANG Junjie, WANG Yiran, JING Yurong, GENG Jieli, ZHI Nan, CAO Wenwei, XU Qun, YU Xiaoping, ZHU Yuan, ZHOU Ying, WANG Lin, GAO Chao, LI Binyin, CHEN Shengdi, YUAN Fang, DOU Ronghua, LIU Xiaoyun, LI Xuena, YIN Yafu, CHANG Yan, XU Gang, XIN Jiawei, ZHONG Yanting, LI Chunbo, WANG Ying, ZHOU Maigeng, CHEN Xiaochun, representing the China Alzheimer's Disease Report Writing Group
    Journal of Diagnostics Concepts & Practice    2024, 23 (03): 219-256.   DOI: 10.16150/j.1671-2870.2024.03.001
    Abstract15554)   HTML1125)    PDF(pc) (3389KB)(12494)       Save

    With the sustained growth of economy and significant changes in social demographics, the issue of elderly-related diseases has increasingly drawn attention particularly. Alzheimer's disease (AD),as a representative disease of neurodegenerative diseases has become a major challenge, affecting the health and quality of life among the elderly population severely. In recent years, the incidence, prevalence, and mortality rate of AD increase in China, imposing substantial economic burdens on families, society, and the entire healthcare system. To proactively address this challenge and respond to the national 'Healthy China Action' initiative, leading experts from Renji Hospital, Shanghai Jiao Tong University School of Medicine,and Chinese Center for Disease Control and Prevention Chronic Non-communicable Disease Control Center, Fudan University School of Public Health, Shanghai Mental Health Center, Ruijin Hospital,Shanghai Jiao Tong University School of Medicine, Fujian Medical University, and other authoritative institutions, have jointly authored the 'China Alzheimer Disease Report 2024'. Building upon previous editions of 2021, 2022, and 2023, this report updates epidemiological data on AD in China, thoroughly analyzes the latest economic burdens of the disease, and comprehensively evaluates the current status of AD diagnosis and treatment services, as well as the allocation of public health resources in our country. The release of the 'China Alzheimer Disease Report 2024' not only reflects China's progress and efforts in AD research and prevention, but also underscores the social heightened concern for elderly health issues. It aims to provide scientific and technical guidance and robust data support for the prevention, diagnosis, and treatment of AD, offering a professional basis for the government and relevant departments to formulate targeted health policies and intervention measures. Furthermore, it serves as a platform for promoting academic exchanges and cooperation in this field domestically and internationally. Through the dissemination and application of this report, we anticipate it will not only serve as a reference for professionals but also enhance public awareness of AD, promote active participation across various sectors of society, and jointly advance the development of elderly health care in China, empowering us towards achieving 'healthy aging'.

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    Interpretation on the report of global stroke data 2022
    TANG Chunhua, GUO Lu, LI Qiong, ZHANG Lili
    Journal of Diagnostics Concepts & Practice    2023, 22 (03): 238-246.   DOI: 10.16150/j.1671-2870.2023.03.06
    Abstract7206)   HTML287)    PDF(pc) (2270KB)(6984)       Save

    In 2022, the World Stroke Organization released two new reports regarding global stroke statistics in the International Journal of Stroke. The reports updated the global incidence and mortality of stroke, evaluated the effects of gender and geographic factors, and provided updated statistics on attributable risk factors associated with stroke. This article briefly interprets the two reports in the context of stroke prevalence and disease burden in China. 2019 Global Burden of Disease Study findings show that stroke remains the second-leading cause of death and the third-leading cause of death and disability combined in the world. From 1990 to 2019, the burden (in terms of the absolute number of cases) increased substantially, with the bulk of the global stroke burden residing in lower-income and lower-middle-income countries. Moreover, people under 70-year-old were observed to have significant increases in stroke prevalence and incidence. The five major risks for stroke globally include high systolic blood pressure, high body mass index, high fasting glucose, environmental particulate matter pollution, and smoking. Stroke prevention and treatment in China are facing great challenges. Stroke has become the leading cause of death and disability among Chinese adults, as well as the leading cause of disability adjusted life year lost. The incidence, prevalence and mortality of stroke in China are geographically high in the north, low in the south and prominent in the central part of the country; the prevalence is higher in rural areas than that in urban areas; the morbidity and mortality rates are higher in men than those in women; the average age of onset is lower than in developed countries; the overall disease burden of ischemic stroke is on the rise, but that of hemorrhagic stroke is on the decline. The awareness of stroke prevention and treatment was low. In conclusion, it is of strategic importance to actively establish a graded stroke prevention and control system that meets the national conditions.

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    Chinese interpretation of Japanese Gastric Cancer Treatment Guidelines 2021 (6th edition) and Ruijin clinical practice
    YAN Chao, LU Sheng, YAN Min, ZHU Zhenggang
    Journal of Surgery Concepts & Practice    2023, 28 (04): 326-354.   DOI: 10.16139/j.1007-9610.2023.04.010
    Abstract1718)   HTML37)    PDF(pc) (4954KB)(6903)       Save

    “Japanese Gastric Cancer Treatment Guidelines” have been important guidelines for the treatment of gastric cancer in Japan and worldwide. The English version “Japanese Gastric Cancer Treatment Guidelines 2021 (6th Edition)” published in January 2023 consists of two parts. The first part includes diagnostic and treatment methods, such as surgery, endoscopic resection, chemotherapy, follow-up. The second part addresses clinical issues, including recommendations and explanations for clinical hot topics. This article will provide a Chinese interpretation of the guidelines and briefly introduce our hospital's clinical practice in the diagnosis and treatment of gastric cancer.

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    Interpretation of the 2022 edition of “guidelines for diagnosis and management of hyperthyroidism and other causes of thyrotoxicosis in China”
    XU Bojin, PENG Wenfang, HUANG Shan
    Journal of Surgery Concepts & Practice    2023, 28 (06): 512-519.   DOI: 10.16139/j.1007-9610.2023.06.05
    Abstract1794)   HTML19)    PDF(pc) (889KB)(5499)       Save

    “Guidelines for diagnosis and management of hyperthyroidism and other causes of thyrotoxicosis in China” (2022) (referred to as the “guidelines”) was officially published in August 2022 in the Chinese Journal of Endocrine Metabolism. These guidelines have been extensively updated from the 2007 version, with 15 sections covering the etiology, clinical manifestations, diagnosis, evaluation, and treatment of hyperthyroidism, as well as the management of specific types of thyrotoxicosis. The new version guidelines proposed 107 recommended opinions supported by stronger evidence, offering comprehensive and reliable guidance for clinical doctors and medical professionals dealing with thyrotoxicosis. This article aimed to extract the key points and recommended strategies from the guidelines to help clinical doctors better understand and apply the latest guiding principles.

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    Evaluation of facial injection filling materials for medical aesthetics
    ZHAO Chenyu, LI Chongchong, SUN Xue, et al
    Journal of Tissue Engineering and Reconstructive Surgery    2023, 19 (5): 517-.  
    Abstract526)      PDF(pc) (874KB)(4883)       Save
    With economic development and technological progress, the demand for medical aesthetics has increased sig
    nificantly, and medical biomaterials are widely used. It is necessary to further improve the evaluation of their effectiveness and
    safety. At present, the evaluation of its physicochemical properties and biology is adopted in China. However, the clinical effec
    tiveness is a multi-faceted evaluation without unified criteria. Most of the evaluation mainly adopts objective indicators for quan
    titative analysis, while subjective feelings are secondary criteria. In this paper, the main facial fillers and the evaluation methods
    of their physicochemical properties were reviewed.
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    DNA methylation detection assists early screening and diagnosis of tumors
    LIU Yifei
    Journal of Diagnostics Concepts & Practice    2023, 22 (04): 393-401.   DOI: 10.16150/j.1671-2870.2023.04.011
    Abstract1834)   HTML43)    PDF(pc) (1010KB)(4032)       Save

    DNA methylation is one of the most widely used indicator for early cancer screening. Under the influence of carcinogens, hypermethylation of the promoter region of tumor suppressor genes may lead to downregulation or silencing of gene expression, thereby activating the expression of proto-oncogenes and promoting tumorigenesis. The samples used for DNA methylation detection are mainly exfoliated cells, blood samples and paraffin-embedded tissues. Commonly used detection methods include: methylation-specific polymerase chain reaction (MSP), nucleic acid mass spectrometry, methylation chip, bisulfite sequencing, next-generation sequencing, etc. Compared with mutation detection, the advantages of DNA methylation detection are that it has higher tumor specificity, more detectable sites, higher signal quality, and can achieve tissue traceability. Currently, it is mainly used clinically for medication guidance for brain glioma, aid in diagnosis and high-risk triage for lung cancer, high-risk triage and recurrence monitoring for bladder cancer, high-risk triage for cervical cancer, and early screening and recurrence monitoring for colorectal cancer and gastric cancer. Before large-scale clinical routine application, accurately positioning of the application scenarios for DNA methylation detection must be considered. For well-tolerated endoscopy, the rigid need of DNA methylation detection for high-risk triage may be reduced. DNA methylation detection plays an important role in assisting in the diagnosis of tumors with low pathological diagnosis sensitivity, tumor monitoring and prognosis assessment. With the standardization of testing procedures and quality management, DNA methylation detection will be more widely used to improve the early screening and diagnostic sensitivity of tumors.

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    New knowledge of prophylaxis and treatment about cancer-associated thrombosis
    DING Yongjie, ZHANG Liu, LI Qingyun
    Journal of Diagnostics Concepts & Practice    2023, 22 (04): 323-331.   DOI: 10.16150/j.1671-2870.2023.04.001
    Abstract646)   HTML23)    PDF(pc) (946KB)(4014)       Save

    Cancer-associated thrombosis (CAT) is the second leading cause of death in cancer patients, second only to the progression of the tumor. It leads to extended hospitalization and re-hospitalization, resulting in a serious social medical burden. Tumor-specific gene mutations such as JAK2, ALK, and KRAS mutations are closely related to the risk of CAT in patients with solid tumors. Patients treated with immune checkpoint inhibitors have a high risk of CAT, with a 1-year cumulative incidence rate of 10.86%. Therefore, accurate risk assessment is important. The Khorana risk score (KRS) is the first model to assess CAT risk and has been validated in several studies. The new generation models are based on the improvement of KRS, but they have not yet undergone large-scale external verification, such as the Vienna CAT model, PROTECHT model, and CONKO model. Due to the strong correlation between tumors and CAT, several CAT-related prevention guidelines have been established domestically and abroad. All of these guidelines recommend that patients undergo preventive anticoagulation therapy after tumor surgery. Low molecular weight heparin (LMWH) is the most widely used anticoagulant drug to prevent CAT. New oral anticoagulants (NOAC) are also used to prevent CAT, despite the incidence of hemorrhaging increases, the overall benefits to patients outweigh the risks. The strategy for treating CAT is complex. For patients with non-gastrointestinal tumors, NOAC can be used as a first-line drug, while LMWH is recommended for anticoagulation in patients with gastrointestinal tumors. Since CAT patients receive anticoagulation and anti-tumor therapy at the same time, drug interactions need to be considered to avoid drug-induced bleeding, especially the impact of combined medication on NOAC pharmacokinetics. The ideal length of anticoagulation therapy for CAT remains unclear. Guidelines recommend that patients with CAT should indefinitely continue the anticoagulation therapy after completing 3 to 6 months of initial anticoagulation therapy. Therefore, when determining the course of anticoagulation therapy for cancer patients, physicians should evaluate the risk of recurrence of thrombosis and bleeding, and optimize the treatment plan.

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    Review of Autonomous Decision-Making and Planning Techniques for Unmanned Aerial Vehicle
    CHENG Haoyu, ZHANG Shuo, LIU Tailai, XU Shengli, HUANG Hanqiao
    Air & Space Defense    2024, 7 (1): 6-15.  
    Abstract852)      PDF(pc) (994KB)(3895)       Save
    Facing the future with a highly dynamic, strong confrontation and rejection combat environment, intelligence level has become the core factor restricting the UAV mission/environment adaptability and combat effectiveness. Focusing on autonomous decision-making and planning technology, which is a difficult, rapidly updated and broad application prospect, the main research achievements and future development direction of autonomous decision-making and planning technology were reviewed. Firstly, the necessity of autonomous decision-making and planning technology research was elaborated based on the development and current situation of unmanned aerial vehicles. Secondly, this study summarized and analyzed the current research results of autonomous decision-making and planning technology. Finally, the development direction of autonomous decision-making and planning technology of UAVs was prospected.
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    Analysis of the Development of Foreign Small Loitering Munitions and Their Early Warning System Response Strategy
    LI Chao, LI Hao, SU Haoran
    Air & Space Defense    2023, 6 (3): 58-65.  
    Abstract545)      PDF(pc) (1082KB)(3804)       Save
    The use of small loitering munitions in the Armenia-Azerbaijan and the Russia-Ukraine conflicts has once again driven the interests of global military powers to develop loitering munitions. Taking foreign small loitering munitions as the main research object, this paper has discussed the development history of loitering munitions, including the development status of several typical small loitering munitions and their respective latest development of operational applications, and summarized and compared their performance parameters. According to the study of typical types of operational applications of small loitering munitions and their operational advantages, countermeasure suggestions were proposed for future early warning systems to cope with small loitering munitions operations, thus providing a reference for the construction and development of early warning systems.
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    The consensus on the diagnosis and treatment of elderly myelodysplastic neoplasm in China (2024)
    MDS Professional Committee of Hematology Branch of Chinese Geriatrics Society
    Journal of Diagnostics Concepts & Practice    2024, 23 (03): 285-296.   DOI: 10.16150/j.1671-2870.2024.03.006
    Abstract1612)   HTML79)    PDF(pc) (1106KB)(3731)       Save

    Myelodysplastic syndromes (MDS) are a heterogeneous group of myeloid tumours originating from haematopoietic stem/progenitor cells, with a high prevalence in the elderly. Epidemiological surveys in Europe and the United States have revealed that the incidence of MDS is (4-5)/100 000, which increases with age,and the median age at diagnosis of MDS patients reaches 73-76 years. In Shanghai, China, according to the World Health Organization (WHO) 2008 diagnostic criteria, the average incidence rate was 1.51/100 000, and the median age of onset of MDS was found to be 62 years old in a survey conducted in 3.9 million people from 2004 to 2007, of which about one-third of the patients would be transformed into acute myeloid leukemia (AML), and 53% of the patients would die due to infections, haemorrhages, or comorbidities triggered by cytopenias. Elderly MDS patients have their own characteristics in terms of both treatment choices and disease prognosis due to more comorbidities and weaker health. Clinical characteristics of elderly MDS patients include slightly higher white blood cell count, haemoglobin level and more bone marrow blasts than those of young patients, while neutrophil count and platelet count are significantly higher than those of young patients; the number of mutations in elderly MDS patients is higher, with an average of 1.8 mutations per patient, among which the mutations in ASXL1, TET2, SF3B1, STAG2, SRSF2 and TP53 are more common; while the number of mutations in younger patients averages 1.2 per person, among which U2AF1, ASXL1 and RUNX1 mutations are more common. Allogeneic haematopoietic stem cell transplantation (allo-HSCT) is the only curative treatment for MDS, and myeloablative transplantation is feasible in young patients, but only reduced-intensity conditioning (RIC) allo-HSCT can be performed in elderly patients.The natural course and prognosis of elderly MDS patients varies considerably, and the MDS Composite Prognostic Score, which is composed of the composite age (>70 years old), vulnerability index, and IPSS prognostic subgroups, is able to better predict the tolerance of chemotherapy and adverse treatment effects in MDS patients. This consensus is based on the latest evidence-based data in the study of MDS in the elderly at home and abroad, and has been discussed by the experts of the group, which aims to standardise the diagnosis and the whole management of treatment for elderly MDS patients in China.

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    Interpretation of the 5th edition of the WHO classification of haematolymphoid tumours on MDS and AML
    YE Xiangjun, LU Xingguo
    Journal of Diagnostics Concepts & Practice    2023, 22 (05): 421-428.   DOI: 10.16150/j.1671-2870.2023.05.002
    Abstract1589)   HTML50)    PDF(pc) (1392KB)(3490)       Save

    In 2022, the World Health Organization (WHO) proposed the 5th edition of the WHO Classification of Haematolymphoid Tumours (referred to as the 5th ed. WHO classification) based on the accumulated research results and clinical application progress in related fields after the revised 4th Edition of the WHO classification. Myelodysplastic neoplasms/syndrome (MDS) and acute myeloid leukemia (AML) in the 5th ed. edition of the WHO classification. In practice in WHO classification has major changes from the revised 4th, it is of great significance for clinical disease diagnosis and treatment, as well as disease registration and scientific research. This article is interpreted based on the fifth edition of the classification published in the journal Leukemia and online ahead of print version on the official website of the International Agency for Research on Cancer.

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    Summary and interpretation of the World Health Organization “Global Report on Hypertension”
    ZHANG Dongyan, LI Yan
    Journal of Diagnostics Concepts & Practice    2024, 23 (03): 297-304.   DOI: 10.16150/j.1671-2870.2024.03.007
    Abstract1969)   HTML54)    PDF(pc) (945KB)(3340)       Save

    In 2023, the World Health Organization (WHO) released the first document of “Global report on hypertension—The race against a silent killer”. which covers the global prevalence and management of hypertension, analyzes the mortality and disease burden caused by hypertension, explores the risk factors for hypertension, evaluates the cost-effectiveness of blood pressure treatment, and presents successful examples of hypertension management in many countries, especially the global implementation of the WHO-launched HEARTS project for hypertension control. Hypertension is a significant global public health challenge with severe health implications. Over the past 30 years, the number of people with hypertension (defined as systolic blood pressure ≥140 mmHg or diastolic blood pressure ≥90 mmHg, or taking antihypertensive medication) has doubled, rising from 650 million in 1990 to 1.3 billion in 2019. Among the global hypertensive population aged 30-79, approximately 54% have been diagnosed, of which 42% are receiving antihypertensive treatment, and only 21% have controlled blood pressure. In 2019, elevated systolic pressure was responsible for over half of cardiovascular disease deaths globally. Increasing the global hypertension control rate to 50% could prevent 76 million deaths from 2023 to 2050. Population-level risk factors for hypertension include high salt and low potassium intake, alcohol consumption, physical inactivity, and air pollution. WHO advocates for the prevention and control of hypertension through measures such as reducing dietary sodium intake, increasing potassium intake, limiting alcohol consumption, quitting smoking, increasing physical activity, and improving air quality. In terms of treatment, WHO guidelines recommend antihypertensive medication for individuals with systolic blood pressure ≥140 mmHg or diastolic blood pressure ≥90 mmHg. For specific populations, it is also recommended to start antihypertensive treatment when systolic blood pressure is between 130-139 mmHg. The use of single-pill combination therapy is also advised to improve adherence and persistence in treatment. The prevalence and management of hypertension in China are also noteworthy. Hypertension is a major cause of mortality and disease burden in the Chinese population. By learning from global successes in hypertension management, China can enhance its efforts in the prevention, control, and monitoring of hypertension, particularly by promoting the application of the HEARTS technical package to improve hypertension management. This report aims to draw attention to major non-communicable diseases, particularly hypertension, as a public health challenge. Through detailed data analysis and successful case studies, the report underscores the importance of hypertension prevention and control, providing scientific evidence for policy-making across countries. This collective effort aims to achieve the global goal of a 25% relative reduction in uncontrolled hypertension prevalence by 2025 compared to 2010. This article will interpret briefly the reports based on the prevalence and management of hypertension in China.

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    Research on the Progress of US Military Digital Transformation
    ZHANG Xue
    Air & Space Defense    2023, 6 (4): 12-16.  
    Abstract1268)      PDF(pc) (639KB)(3217)       Save
    Digital transformation is strategically required by military transformation. It’s critical to guarantee the reform of military concepts and plays an indispensable link in winning future wars using intelligent technology. To maintain the war advantage, the US military has been actively promoting its digital transformation during the transition of the fourth industrial revolution. This paper has studied the needs, development goals, significance, and implementation approaches of the digital transformation of the current US Army. Then, specific strategies to promote the digital transformation of China’s military were proposed by establishing standards and specifications, building data models, and personnel digital literacy.
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    Urban Target Detection Algorithm Based on Multi-Modal Fusion of UAV
    WANG Jianyuan, CHEN Xiaotong, ZHANG Yue, SUN Junge, SHI Donghao, CHEN Jinbao
    Air & Space Defense    2024, 7 (1): 32-39.  
    Abstract900)      PDF(pc) (1812KB)(3072)       Save
    Using small drones to detect urban targets such as vehicles at low altitudes in cities has gradually become a mainstream means. Given the existing problems of low detection accuracy of single-mode detection networks affected by visible light detection, inability to work at night and the blurred edge of infrared detection targets in actual scenes, this paper has proposed a multi-modal UAV detection algorithm based on image fusion and deep learning network. Firstly, based on the DUT-VTUAV visible-infrared registration data set and TIF image fusion algorithm, a multi-mode fusion data set was built up. Secondly, by comparing the detection accuracy, speed and several parameters of the existing YOLO series network, the lightweight network YOLO v5n which was most suitable for the mobile deployment of UAVs was decided. Finally, a multi-modal fusion detection algorithm was produced by combining an image fusion algorithm and a target detection model. Comparative experiments on vehicle data sets successfully show that compared with single-mode detection, the detection accuracy of the proposed algorithm is effectively increased, with mAP up to 99.6%, and a set of visible-infrared image fusion detection can be completed within 0.3s, indicating the high real-time performance.
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    Fault Detection in Power Distribution Systems Based on Gated Recurrent Attention Network
    CHEN Haolan, JIN Bingying, LIU Yadong, QIAN Qinglin, WANG Peng, CHEN Yanxia, YU Xijuan, YAN Yingjie
    Journal of Shanghai Jiao Tong University    2024, 58 (3): 295-303.   DOI: 10.16183/j.cnki.jsjtu.2022.091
    Abstract348)   HTML13)    PDF(pc) (2938KB)(3018)       Save

    To improve fault identification accuracy in power distribution systems, a model named gated recurrent attention network is proposed. First, a higher weight is put on the key cycles of fault phase based on the attention mechanism, making the model focus more on these key messages by weight assignment. Then, the gated recurrent network is adopted, which controls the memory transmission with gate signal and constructs the relationship between input waveform and probability of events at different stages to process the waveform sequence, thereby improving recognition accuracy. Experiments based on both simulation and field data show that the proposed method, under the small-sample-learning condition, is much better than other commonly-used classification models, such as support vector machine, gradient boosting decision tree, and convolutional neural network, providing new insights into fault identification technology in power distribution systems.

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    Research progress on the mechanism of skin aging caused by ultraviolet radiation
    CHEN Heng, WANG Jue, ZHOU Xu
    Journal of Tissue Engineering and Reconstructive Surgery    2024, 20 (3): 382-.  
    Abstract334)      PDF(pc) (992KB)(2992)       Save
    Skin exposed to sunlight for a long period of time will have impaired function and even genetic material
    alteration, which is manifested by aging characteristics such as water loss, elasticity loss, wrinkle growth, melanin
    deposition and dryness. There are many ways to cause skin photoaging and the mechanism is complex, the ultraviolet light in
    sunlight has a particularly obvious effect on skin aging, the ultraviolet light that can act on the skin is divided into two kinds:
    UVA and UVB. They mainly act on the skin through five mechanisms that lead to photoaging: oxidative stress, damaging
    genetic material, changing the epidermal microbial community, destroying the function and structure of organelles, and
    reshaping the extracellular matrix (ECM).In this paper, these five mechanisms were reviewed, and research directions and
    prospects in this field were proposed.
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    Ekphrasis in the Oral Tradition: The Mongolian Epic as an Example
    A Jingsi
    Contemporary Foreign Languages Studies    2023, 23 (5): 185-192.   DOI: 10.3969/j.issn.1674-8921.2023.05.019
    Abstract295)   HTML3)    PDF(pc) (1431KB)(2974)       Save
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    Review of Missile Structural Optimization Design for Additive Manufacturing
    KE Linda, ZHANG Xiaolong, CUI Zhe, GU Mingfeng, LAI Caifang, LIU Yong
    Air & Space Defense    2023, 6 (2): 28-34.  
    Abstract567)      PDF(pc) (1107KB)(2961)       Save
    With the development of AM (additive manufacturing) technology, the integration of innovative structure design and AM technology must be the critical direction of breakthrough development in missile development and structural design. This paper discussed the application of advanced additive manufacturing technology in missile structure optimization in three parts: the static design, the dynamic structure design and the coupling dynamics. Since the optimization of missile structure involves dynamic characteristics, aeroelasticity, mechanical-thermal coupling etc., relying on its unique advantages, AM technology can break through the traditional design mode and the processing bottleneck, and can further realize the lightweight, small size and functional integration of space weapon equipment.
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    Joint Policy Optimization of Quality Control, Condition-Based Maintenance and Spare Ordering for a Degradation System
    HAN Mengying, MA Shugang, YANG Jianhua, LI Wei, MA Zhichao
    Journal of Shanghai Jiao Tong University    2024, 58 (3): 361-370.   DOI: 10.16183/j.cnki.jsjtu.2022.356
    Abstract235)   HTML9)    PDF(pc) (5697KB)(2903)       Save

    A joint policy of quality control, condition-based maintenance and spare ordering is proposed for a degradation system subject to the delay time concept. First, considering the fact that product quality is largely dependent on system state, a two-stage inspection policy is proposed, in which the system state is detected during the initial deterioration process, but the product quality is checked after the defective state is found by an inspection. Then, based on the condition inspection information, quality information and failure information, the corresponding maintenance activity is chosen. Combining the state of the spare part when the system replacement is required, all possible events during an inspection interval are discussed and then a mathematical model of average cost rate is established. Afterwards, a simulation-based optimization approach coupling discrete event simulation and response surface methodology is devised to obtain a near optimal joint policy. Finally, a numerical example is provided to demonstrate the effectiveness and applicability of the proposed policy by comparing it with the comparative policy.

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    The Enlightenment for the Development of Anti-UAV Equipment from the Offensive and Defensive Operations of UAVs Between Russian and Ukrainian
    ZHANG Yaoyi, LI Ning
    Air & Space Defense    2024, 7 (3): 34-39.  
    Abstract800)      PDF(pc) (924KB)(2803)       Save
    According to the offensive and defensive operations of UAVs (Unmanned Aerial Vehicles) in the conflict between Russia and Ukraine, the methods of countering new air threats represented by UAVs in the future were studied. By reviewing the overall situation of the UAVs employed by Russia and Ukraine, the methods of using various UAVs to build an integrated reconnaissance and offensive system on both sides were summarized. From the perspective of responding to the UAV threat, this paper elaborated on the overall overview of the anti-UAV equipment employed by both sides and summarized the methods of building an integrated anti-UAV system using various soft and hard killing methods. According to the practical experience of warfare, considering the development of strong hostile UAVs and anti-UAV equipment such as the US military, enlightenment and suggestions for the future development of anti-UAV equipment were proposed.
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    Review of Equipment Effectiveness Evaluation and Supporting Technologies
    SU Hongjia, LUO Yucheng, LIU Fei
    Air & Space Defense    2023, 6 (3): 29-38.  
    Abstract948)      PDF(pc) (619KB)(2743)       Save
    Operational effectiveness evaluation has been widely used in various weapon and equipment validation studies to assess the capability of specific operational mission objectives. This paper has provided a summarized analysis of the current problems and challenges. Then, it reviewed three categories of equipment system operational effectiveness evaluation methods: multi-attribute decision-making, complex networks, and machine learning algorithms. The research status of the above approaches was analyzed. In addition, this paper has summarized the supporting technologies for equipment system operational effectiveness evaluation, respectively, indicator reduction and optimization. Finally, according to the current research progress, expected research directions for future evaluation are proposed.
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    Research on Hierarchical Tree Construction Method for Multilevel Process Model of Joint Operations Simulation
    ZHANG Mingxin, SU JiongMing, ZHANG Mingen, LI Rufei, QIAN Xiaochao
    Air & Space Defense    0, (): 6-12.  
    Abstract291)      PDF(pc) (1041KB)(2648)       Save
    The types of models of the joint combat simulation experiments are rich, while the design, the evaluation and the analysis of the simulation experiment are complex. Thus, the scenarios for the application of the experimental results are diverse. Therefore, multi-level models are required for joint combat experiments and analysis. The hierarchy of entities has been generally studied by aggregation and disaggregation but still lacks suitable description, analysis, and integration methods for the hierarchy of combat processes models. According to the existing methods of hierarchical description and analysis, this paper utilized the concept of a hierarchical tree to describe the process models of different levels. The structure, operation and application of the hierarchical tree were analyzed systematically. The specific application of the process hierarchical tree was introduced with examples. The hierarchical tree description of the process model can contribute to the multi-level joint simulation application analysis and multi-level model management, and can effectively improve the interoperability and reusability of models at different levels.
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    Research progress of three-dimensional functional skin model construction in vitro
    LI Yang, XI Taotao, ZHANG Bo, et al
    Journal of Tissue Engineering and Reconstructive Surgery    2024, 20 (2): 240-.  
    Abstract210)      PDF(pc) (1034KB)(2603)       Save
    Tissue engineering technology has been widely used in tissue and organ repair and has become an important
    method of regenerative medicine technique. The appearance of tissue engineering skin provides a new method for the
    treatment of large-area cutaneous defect in clinic. Because of the complicated skin-structure, it is an enormous challenge to
    building a functional three-dimensional skin tissue engineering model to simulate or replace the original skin. Based on this,
    from the aspects of cell types and sources, techniques, types, applications and prospects of skin tissue engineering models,
    the latest progress of in vitro 3D functional skin tissue model construction was reviewed in order to provide a theoretical basis
    for the construction of ideal skin tissue model.
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    AC loss study on a 3-phase HTS 1 MVA transformer coupled with a three-limb iron core
    Yue Wu, Shuangrong You, Jin Fang, Rodney A. Badcock, Nicholas J. Long, Zhenan Jiang
    Superconductivity    2024, 10 (0): 100095-.   DOI: 10.1016/j.supcon.2024.100095
    Abstract481)   HTML446)    PDF(pc) (4938KB)(2524)       Save

    High-temperature superconducting (HTS) technology provides an alternative approach to achieve compact transformers. Addressing AC loss in the HTS winding is crucial for HTS transformer applications. Most numerical AC loss studies on HTS transformers have neglected the influence of iron cores. This work carries out an AC loss study to explore the impact of an iron core on the HTS windings in a 3-phase HTS 1 MVA transformer coupled with it. AC loss simulations for the transformer winding both with and without the iron core are conducted by adopting the three-dimensional (3D) T-A homogenization method. When the iron core is incorporated, the saturation magnetic fields of iron materials, flux diverters (FDs) with different geometries, and variations in turn spacings in the LV winding composed of Roebel cables are considered to investigate their influence on the AC loss of the transformer winding. The inclusion of the iron core leads to a 1.2% increase in AC loss for the transformer winding while simulating at the rated current. We attribute this slight difference to the non-inductive winding structure of the transformer winding, where a strong magnetic field generated in the space between the LV and HV windings effectively shields the influence of the iron core.

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    The Construction of Student-Centered, Harmonious Teacher-Student Relationships Driven by Educator Spirit
    XU Jinfen
    Contemporary Foreign Languages Studies    2024, 24 (4): 5-15.   DOI: 10.3969/j.issn.1674-8921.2024.04.001
    Abstract415)   HTML18)    PDF(pc) (1217KB)(2502)       Save

    Under the guidance of spirits of educators, this article firstly explores the contemporary significance and theoretical basis for the construction of harmonious teacher-student relationships. Then, based on the 14 student-centered principles proposed by the American Psychological Association and the semi-structured interview results with university teachers and students from different regions in China, six major characteristics of student-centered harmonious teacher-student relationships are extracted. Finally, guided by these characteristics, specific strategies for building student-centered harmonious relationships between foreign language teachers and students are proposed from five aspects: educational philosophy, teaching methods, learning environment, emotional support, and evaluation system. This article aims to provide references for foreign language teachers from both theoretical and practical perspectives and further promote the healthy development of foreign language education.

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    Expert consensus on neuroimaging diagnosis of dementia and cognitive impairment (2023)
    Aging and Cognitive Impairment Branch of Shanghai Society of Aging and Degenerative Diseases
    Journal of Diagnostics Concepts & Practice    2024, 23 (01): 30-39.   DOI: 10.16150/j.1671-2870.2024.01.005
    Abstract1119)   HTML11)    PDF(pc) (9441KB)(2457)       Save

    For patients with cognitive impairment as the main clinical manifestation, structural MRI (or CT instead) should be performed first to clarify intracranial lesions and brain atrophy. For patients with specific clinical manifestations, specific MRI sequences is recommended to further assist diagnosis. If the patient is suspected of AD, it is recommended to perform oblique coronal T1WI for MTA grading to score medial temporal lobe atrophy. If the patient is suspected to be caused by vascular factors or special infections (prion proteins), it is recommended to perform diffusion-weighted imaging. If the patient has extrapyramidal symptoms or small vessel disease, especially cerebral amyloid angiopathy or cognitive impairment complicated by diabetes, it is recommended to perform susceptibility-weighted imaging. If a mass is suspicious on MRI, contrast-enhanced MR imaging and MR spectroscopy should be performed. If the patient has amyotrophic lateral sclerosis, it is recommended to perform diffusion tensor imaging. If the patient is suspected to be caused by neurodegenerative diseases, it is recommended to perform 18F-FDG PET and Aβ-PET or tau-PET. Aβ-PET imaging and tau-PET imaging can visualize the degree and scope of pathological protein deposition in the brain, which has important predictive and diagnostic value for dementia and can be used for the differential diagnosis of dementia and staging the disease progression. In addition, resting-state functional magnetic resonance imaging, near-infrared spectroscopy, and some emerging imaging techniques such as cine phase-contrast magnetic resonance imaging, and diffusion tensor image analysis along the perivascular space have been studied in patients with cognitive impairment. It is expected that these technologies can be used in the future to better assist the diagnosis and differential diagnosis of cognitive impairment. It should be noted that neuroimaging does not represent the complete diagnosis and clinical symptoms of the disease and must be interpreted with caution.

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    Development of the Intelligentization of Precision Strike System of Systems
    FAN Jinxiang, LIU Yiji, LI Ning, CHAI Juanfang
    Air & Space Defense    2023, 6 (4): 1-11.  
    Abstract613)      PDF(pc) (831KB)(2425)       Save
    In recent years, to accommodate the operational modes being transformed to multi-domain/all-domain joint operation and the weapon equipment being transformed to systematic and cooperative, and to improve the capability of precision strike system of systems in joint-operation and fighting against powerful enemies, USA and other major military powerful countries are making great efforts to carry out the research and development together with preliminary application of intelligentization of precision strike system of systems. They have successfully applied artificial intelligence(AI) in commerce, industry, science and other fields. In this paper, the development of the intelligentization of precision strike systems has been reviewed. The requirements for the intelligentization of advanced precision strike system of systems were investigated. The overall development of intelligentization in the information support system and its engagement chain of precision strike systems were summarized. The key technologies for the intelligentization of precision strike systems were discussed.
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    Clinical characteristics and risk factor analysis of 118 patients with cerebral venous sinus thrombosis
    LI Lei, WU Xi, DAI Jing, WU Wenman, DING Qiulan, WANG Xuefeng
    Journal of Diagnostics Concepts & Practice    2023, 22 (03): 261-269.   DOI: 10.16150/j.1671-2870.2023.03.09
    Abstract348)   HTML13)    PDF(pc) (991KB)(2406)       Save

    Objective: To analyze the clinical characteristics and thrombotic risk factors of cerebral venous sinus thrombosis (CVST) in Chinese population, in order to provide reference for the clinical diagnosis, prevention and treatment of CVST. Methods: A total of 118 CVST patients who visited the Thrombosis and Hemostasis Clinic of Ruijin Hospital from January in 2015 to December in 2022 were enrolled. The clinical data, imaging characteristics, and thrombotic gene panel were collected, and independent risk factors for thrombosis, recurrence, and multi-site thrombosis in CVST patients were studied through univariate and multivariate logistic regression. Results: Among 118 CVST patients, 88.1% (104/118) patients firstly developed CVST at age younger than 45 years old.It revealed that 57.6% patients (68/118) only suffered CVST once,and 33.1% patients (39/118) experienced thrombotic events at least twice, while 37.3% patients (44/118) suffered multi-site venous thromboembolism (VTE). The superior sagittal sinus was the most common venous sinus to form thrombosis (77/118), and multi-sites of venous sinus were involved simultaneously in 54.2% patients (64/118). The risk factor screening for thrombophilia showed that 70.3% patients (83/118) carried at least one thrombotic risk factor, including 53.3% patients (63/118) with inherited risk factors and 32.2% patients (38/118) with acquired risk factors. The main risk factors for males were anticoagulant protein deficiency (35/66) and antiphospholipid syndrome (5/66), while the risk factors for females mainly included anticoagulant protein deficiency (20/52), pregnancy/postpartum period (11/47), and contraceptive use (5/47). Among 35 patients with unknown risk factors, more than 30% of them experienced recurrent or multi-site thrombosis, and the underlying etiology in these patients still need to be further investigated. Univariate and multivariate logistic regression analysis showed that both inherited risk factors (odds ratio, OR=21.643, 95% confidence interval, CI 9.455-49.544, P<0.0001) and acquired risk factors (OR=10.836, 95% CI 4.306-27.270, P<0.0001) were independent risk factors for the occurrence of CVST. Genetic risk factor (OR=2.270, 95% CI 1.021-5.048, P=0.044) was an independent risk factor for recurrent thrombosis in CVST patients. Conclusions: In Chinese population, CVST is more common in middle-aged and young populations.,with 70.3% patients carrying at least one thrombotic risk factor. Genetic risk factors are the main cause of CVST in China and the detectable rate is 53.3%, which is significantly higher than that (22%) reported abroad. The patients with genetic risk factors have a significantly increased risk of developing CVST or recurrent thrombosis. Identification of thrombotic risk factors, prevention, diagnosis and treatment should be carried out earlier for individuals with high-risk CVST.

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    Development and prospects of ERCP in China
    LI Wen
    Journal of Surgery Concepts & Practice    2023, 28 (04): 279-282.   DOI: 10.16139/j.1007-9610.2023.04.001
    Abstract1268)   HTML19)    PDF(pc) (838KB)(2374)       Save

    Endoscopic retrograde cholangio-pancreatography (ERCP) is an interventional endoscopic technique aimed at the diagnoses and treatment of biliary and pancreatic diseases under the guidance of endoscopy and X-ray ima-ging. ERCP was introduced into China from the 1970s. In the 1990s, ERCP was gradually popularized and applied in China with the development of medical technique and improvement of equipment, more medical institutions started to carry out ERCP. After 2000, ERCP technology and equipment were further upgraded and improved in China. Many secondary and tertiary hospitals began to establish the ERCP centers. Meanwhile, workshops and training also facilitated the teaching and practice of ERCP and cultivated more professionals of ERCP. In recent years, the technical level of ERCP in China has been continuously improved, and technologies and equipments are constantly updated and iterated. Currently, ERCP has become one of important techniques in the endoscopic field, playing an important role in the diagnosis and treatment of biliary and pancreatic diseases. The vigorous development of ERCP in China is attributed to the advancement of medical science, the improvement of technology and the efforts of generations of ERCP specialists.

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    Superconducting nanostrip single photon detectors fabricated of aluminum thin-films
    Yuting Jiang, Xingyu Zhang, Hui Zhou, Xiaofu Zhang, Hao Li, Lixing You
    Superconductivity    2024, 10 (0): 100096-.   DOI: 10.1016/j.supcon.2024.100096
    Abstract166)   HTML162)    PDF(pc) (1122KB)(2332)       Save

    We systematically investigated the detection performance of Al nanostrips for single photons at various wavelengths. The Al films were deposited using magnetron sputtering, and the sophisticated nanostructures and morphology of the deposited films were revealed through high-resolution transmission electron microscopy. The fabricated Al meander nanostrips, with a thickness of 4.2 nm and a width of 178 nm, exhibited a superconducting transition temperature of 2.4 K and a critical current of approximately 5 μA at 0.85 K. While the Al nanostrips demonstrated a saturated internal quantum efficiency for 405-nm photons, the internal detection efficiency exhibited an exponential dependence on bias current without any saturation tendency for 1550-nm photons. This behavior can be attributed to the relatively large diffusion coefficient and coherence length of the Al films. By further narrowing the nanostrip width, the Al-SNSPDs remain capable of effectively detecting single telecom photons to facilitate practical applications.

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    Numerical modelling of electromechanical coupling behaviors in HTS coil with implementation of H formulation in FE software
    Huadong Yong, Dong Wei, Yunkai Tang, Donghui Liu
    Superconductivity    2024, 10 (0): 100097-.   DOI: 10.1016/j.supcon.2024.100097
    Abstract399)   HTML378)    PDF(pc) (3029KB)(2266)       Save

    (Re)Ba2Cu3O7-x (REBCO) coated conductors (CCs) have attracted considerable concern because of their outstanding current carrying capacity in magnetic fields of high strengths. A huge electromagnetic force is generated in the superconducting coil when conducting large currents in strong magnetic field. Thus, management of stress and strain has become a key technical challenge for the stability and safety of superconducting coil during operation. To accurately predict the electro-magnetic and mechanical characteristics of superconducting coil in strong magnetic field, an electromechanical model on the basis of the H-formulation and arbitrary Lagrangian-Eulerian (ALE) method is proposed here with FE software. To verify the proposed model, the simulation outcomes of the coil during magnetization are compared with the experimental outcomes. The coupling effect of magnet at high field strengths is dependent on the position of the coil. To reduce the screening current effect, the overshoot method with plateau is found superior to the traditional overshoot method, and an increase in the stabilization time can decrease the maximum value of stress. Finally, the electromechanical behaviors of single winding coil and two-tapes co-winding coil are compared.

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    Pressurization, intercalation, doping, and elements: An empirical study of superconductivity near perturbation onsets
    Shermane M. Benjamin
    Superconductivity    2024, 10 (0): 100098-.   DOI: 10.1016/j.supcon.2024.100098
    Abstract161)   HTML133)    PDF(pc) (1976KB)(2257)       Save

    Superconductivity is a phenomenon arising from cooperative electron behavior. However, correlations among (1) the minimum tuning parameter required for emergence, (2) the superconducting transition temperature resulting from minimal tuning, and (3) the host's physical/chemical properties still elude the scientific community. Recent empirical investigations, such as those revealing ideal gas-like correlations at the onset of superconductivity in intercalated superconductors, motivate this study. Our investigation reports similar findings in systems (>170 compounds) exhibiting superconductivity through other perturbative means, such as single-element doping. In general, statistical measures, including distance correlation analyses (≠ linear regression fit) of thermodynamic variables, indicate the presence of empirical relationships near the superconducting onset of systematically tuned compounds. These relations involve unit cell volume (V), the number of valence electrons (N), and the superconducting transition temperature (Tc). Note: The author's primary aim is not to validate or challenge BCS theory; it is instead to focus on leveraging methodology led by available data to enhance the exploration and development of innovative and cost-effective superconductors.

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    New advances in the study of scaffold materials for cartilage tissue engineering
    YUE Guangren, WANG Ximei, LI Yu
    Journal of Tissue Engineering and Reconstructive Surgery    2023, 19 (4): 408-413.  
    Abstract446)      PDF(pc) (875KB)(2241)       Save
    Lacking blood vessels and nerve nourishment, cartilage has limited ability to repair and regenerate. Combining scaffolds, cells and active factors, tissue engineering has been considered as an important new direction for repairing cartilage injury. Scaffold plays an important role in the cartilage regeneration process, not only providing a support site for cell adhesion, but also improving the local microenvironment and affecting cell proliferation and differentiation. Many materials have been used to make biodegradable scaffolds: natural materials, synthetic materials and composite materials. In this paper, the materials that have been relatively widely used in cartilage tissue engineering were reviewed so as to provide valuable reference for researchers in this field.
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    Current Developments in Foreign Hypersonic Vehicles and Defense Systems
    Air & Space Defense    2023, 6 (3): 39-51.  
    Abstract581)      PDF(pc) (2112KB)(2234)       Save
    With the evolution of combat modes and advancements in hypersonic-related technologies, hypersonic vehicles have emerged as the major threat in future warfare. This will inevitably trigger new tactical strategies and military doctrines. This paper has provided a systematic review of the development of hypersonic vehicles from major military powers and introduced its current stage of equipment for defense systems. Based on the above analysis, this paper proposes three defending strategies against hypersonic vehicles, which includes building a comprehensive information network, creating an all-encompassing interception posture, and improving a full-factor command and control platform. These strategies contribute to the reference for the construction and development of hypersonic vehicle defense systems and are valuable to counter the growing threat posed by hypersonic vehicles in future warfare.
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    Analyzing the Linguistic Landscape in Ethnic Minority Areas from the Perspective of Sociolinguistics of Globalization:A Case in Daozhen Gelao and Miao Minority County
    WANG Huoyan, TONG Xiuwen
    Contemporary Foreign Languages Studies    2024, 24 (1): 69-80.   DOI: 10.3969/j.issn.1674-8921.2024.01.05
    Abstract493)   HTML6)    PDF(pc) (1300KB)(2226)       Save

    Taking the linguistic landscape on Yinzhen Avenue in Daozhen Gelao and Miao Autonomous County of Guizhou province as a sample, this paper discusses the linguistic landscape in the urban center of ethnic minority areas with a focus on English use within the framework of the three core concepts of mobility, standardization and localization from the perspective of sociolinguistics of globalization. Through the statistical analysis of the language distribution proportions on the 240 collected linguistic signs, it is found that English is the second language after Chinese and has higher visibility and mobility than minority languages. Findings also show the low degree of standardization as well as the large proportion and high degree of localization in English use, which reflects the role of English in the linguistic landscape in presenting Chinese native culture and manifesting the Chinese people's cultural confidence and national identity, and discloses the low education level and the endangerment of ethnic minority languages. Such results have certain practical significance for knowing the language ecology in ethnic minority areas, and promoting the revision and implementation of national language planning and language policies.

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    The Interpretation of Knowledge Reproduction in the English Translation of TOU-KUNG Series Terms in A Pictorial History of Chinese Architecture
    TIAN Hua, LIU Yingchun
    Contemporary Foreign Languages Studies    2024, 24 (1): 49-58.   DOI: 10.3969/j.issn.1674-8921.2024.01.003
    Abstract363)   HTML11)    PDF(pc) (1672KB)(2187)       Save

    The traditional Chinese architectural terms and the basic elements of traditional architectural knowledge, are critical to whether traditional Chinese architectural knowledge can be cross-culturally reproduced effectively or not. Transknowletology defines translation as cultural behavior and social practice of cross-language knowledge processing, reconstruction and retransmission. From the perspective of Transknowletology and based on descriptive method, this paper explores the adoption of translation strategies and its reasons for the traditional Chinese architectural terms by taking English translation of the TOU-KUNG series terms in A Pictorial History of Chinese Architecture as examples to reveal the cross-culture reproduction pattern for transforming local traditional Chinese architectural knowledge into global knowledge. The research results indicate that the English translation strategies for TOU-KUNG series terms are as follows: transliteration as the dominating method, the construction of context, systematic expression and image-text interpretation. The analysis shows that the adoption of English translations strategies is influenced by the internal and external factors such as the historical background, the translation purpose, the translator's accomplishment and context. The paper has certain reference value to the globalization of local knowledge and the mutual learning of civilizations.

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    A Brief Summary of Key Points for The Installation of Offshore Wind Turbine Monopile Foundation
    FAN Changhui
    Ocean Engineering Equipment and Technology    2023, 10 (2): 1-7.   DOI: 10.12087/oeet.2095-7297.2023.02.01
    Abstract521)      PDF(pc) (6154KB)(2179)       Save
    The installation of offshore wind turbine monopile foundation requires a variety of ship machinery and lifting equipment, etc. If the suitabe selection of those above matters could make the completion of the construction objectives be achieved. In order to select suitable ship machinery lifting equipment, using project as example the compare between domestic and foreign monopile installation, the selection consideration of the main floating crane ship and the drivability of the hydraulic hammer are specifically analyzed through the verification analysis of the monopile stabilizing platform and the description of other additional installation points, which shows that the main considerations for the selection of marine machinery and lifting equipment for offshore wind turbine monopile installation in China and the verification analysis methods are useful. These can provide serve as for the selection of marine floating machine for monopile installation, for the design and verification of monopile stabilizing platform, and for the preparation of construction organization and scheme.
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    Overview of Foreign Simulation VV&A Standards
    WANG Bingheng, LI Wei, ZHANG Huan, MA Ping, CHENG Huichuan, ZHANG Jianchao, YANG Ming
    Air & Space Defense    2023, 6 (3): 13-24.  
    Abstract723)      PDF(pc) (1612KB)(2177)       Save
    With the progress of technology, the engineering system has become increasingly sophisticated and complex. Whether the simulation can represent real entities in the real world has been considered as a major concern. Simulation VV&A is the key to ensuring the correctness and credibility of a simulation. The VV&A standard regulates how to perform its work and standardize its activities, which has engineering practical significance. This article initially summarized the development process of foreign VV&A standards. Then, the similarities and differences between simulation VV&A standards abroad were compared and analyzed. Finally, the future development direction of simulation VV&A standards was proposed.
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    Key Technologies and Breakthrough Path of Hydrogen Production by Offshore Wind Power
    GAO Chang, LI Hongtao
    Ocean Engineering Equipment and Technology    2023, 10 (2): 89-94.   DOI: 10.12087/oeet.2095-7297.2023.02.14
    Abstract679)      PDF(pc) (2904KB)(2136)       Save
    Marine renewable energy is abundant but difficult to store. The generation of green hydrogen from offshore renewable energy can provide a new idea for the storage of green energy. This paper mainly analyzes the key technologies of hydrogen production from offshore wind power, focusing on the four aspects of offshore water electrolysis hydrogen production technology, offshore hydrogen energy storage and transportation technology, offshore hydrogen production and storage equipment design, as well as offshore hydrogen production and storage scheme. This paper compares and summarizes the key technologies of offshore wind power hydrogen production in China, and puts forward relevant countermeasures and suggestions on this basis. It provides reference for the innovative development of offshore wind power hydrogen production technology and equipment in China.
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    Interpretation of guidelines for the diagnosis and treatment of primary osteoporosis (2022 version) in China: essential introduction
    ZHANG Zhenlin, YUE Hua, LI Mei, XIA Weibo
    Journal of Diagnostics Concepts & Practice    2023, 22 (03): 230-233.   DOI: 10.16150/j.1671-2870.2023.03.04
    Abstract876)   HTML17)    PDF(pc) (913KB)(2118)       Save

    China is now witnessing an accelerated aging process,and active reaction is an important issue that we are facing. Osteoporosis and the resulting fractures are particularly noteworthy. In order to further standardize the diagnosis and treatment of primary osteoporosis, the Osteoporosis and Bone Mineral Disease Branch of the Chinese Medical Association has developed and released the “Guidelines for the Diagnosis and Treatment of Primary Osteoporosis (2022 Version)” based on the epidemiological characteristics and pathogenesis of the Chinese population, which combined high-quality medical research evidence from both domestic and foreign sources. Based on evidence-based medicine evidence, and clinical practice in China, this article will focus on the interpretation of two key clinical issues in the new version of the guidelines, namely “fracture risk stratification and treatment selection” and “treatment course of anti-osteoporosis drugs”. Regarding the risk of fractures, this guideline divides it into high and extremely high fracture risks, cancels the classification of low and medium risks, and for one of the extremely high fracture risk indicators “recent brittle fractures”,defines “recent” as “24 months”.Given that the FRAX model underestimates the fracture risk of Chinese patients, it is proposed to develop a highly operational fracture risk stratification criteria in clinical practice. Regarding drug treatment, patients who use bisphosphonates should be fully evaluated before entering the medication holiday, and regular follow-up is still required. Although the Food and Drug Administration (FDA) of the United States has lifted the warning of osteosarcoma and 24- month treatment limit for terlipide, the user manual of the drug in China still suggests a treatment period of 24 months. This guideline is based on high-quality evidence-based medical evidence both domestically and internationally, and may provide reference and research directions for clinical practice.

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